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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor racemic'

Search results for: 'p53 and mdm2 proteins interaction inhibitor racemic'

Items 61-70 of 162

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  1. MI-77301 (SAR405838)
    B4984 MI-77301 (SAR405838)
    Summary: orally available MDM2 antagonist
      ≥17.2 mg/mL
  2. p-nitro-Pifithrin-α
    C3846 p-nitro-Pifithrin-α
     1 Citation
    Summary: inactivator of p53
      ≤1 mg/mL
  3. p-nitro-Cyclic Pifithrin-α
    C5104 p-nitro-Cyclic Pifithrin-α
    Summary: inactivator of p53
      ≤1 mg/mL
  4. (±)-Nutlin-3
    B6058 (±)-Nutlin-3
    Summary: MDM2 antagonist, potent and selective
      ≥50.1 mg/mL
  5. ReACp53
    B6198 ReACp53
    Summary: inhibit p53 amyloid formation
      Soluble in DMSO
  6. Embelin
    A8235 Embelin
    Summary: XIAP inhibitor,cell-permeable
  7. (+)-Apogossypol
    B4902 (+)-Apogossypol
    Target: Bcl-2
    Summary: inhibitor of Bcl-2 family proteins
      insoluble in H2O; ≥16.2 mg/mL
  8. NSC59984
    B6045 NSC59984
    Summary: Restores the p53 signaling pathway
      Soluble in DMSO
  9. COTI-2
    C4483 COTI-2
    Summary: activates mutant forms of p53
      ≤1 mg/mL
  10. Bcl Family Set I
    A9902 Bcl Family Set I
    Summary: Bcl family inhibitors

Items 61-70 of 162

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  1. Category Apoptosis Remove This Item
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Category
  1. Caspase 23item
  2. 14.3.3 Proteins 1 item
  3. Apoptosis Inducers 16item
  4. Bax 5item
  5. Bcl-2 Family 26item
  6. Bcl-xL 7item
  7. c-RET 8item
  8. IAP 7item
  9. KEAP1-Nrf2 1 item
  10. MDM2 13item
  11. p53 38item
  12. PC-PLC 4item
  13. PKD 5item
  14. RasGAP (Ras- P21) 1 item
  15. Survivin 2item
  16. Thymidylate Synthase 2item
  17. TNF-α 11item
  18. Other Apoptosis 4item
  19. APC 1 item
  20. PD-1/PD-L1 interaction 3item
  21. ASK1 3item
  22. PAR4 1 item
Specificity
  1. Selective 43item
Reversibility
  1. Reversible 1 item
  2. Irreversible 9item
Target
  1. Caspases 13item
  2. Proteasome 1 item
  3. Histone Deacetylases (HDACs) 2item
  4. Inhibitor of apoptosis proteins (IAP) 2item
  5. Bcl-2 8item
  6. Raf 2item
  7. Aurora Kinases 1 item
  8. Bcl-xl 3item
  9. MDM2 2item
  10. VEGFR 3item
  11. PDGFR 3item
  12. c-Kit 2item
  13. RET 1 item
  14. Mcl-1 7item
  15. Thymidylate Synthase 1 item
  16. Bcr-Abl 1 item
  17. Nrf2 1 item
  18. Sir2-like Family Deacetylases (Sirtuins) 1 item
  19. Deubiquitinating enzymes (DUBs) 1 item
  20. RIP kinases 1 item
  21. PD-1/PD-L1 interaction 1 item
  22. Survivin 1 item
  23. Dehydrogenase 1 item
  24. Autophagy 1 item
  25. Mixed lineage kinase domain-like protein (MLKL) 1 item
  26. Apoptosis Inducers 1 item
  27. angiogenesis 1 item
  28. c-RET 1 item
  29. Bfl-1 1 item
  30. p53-MDM2 interaction 2item
  31. p53 7item
  32. cysteine protease 1 item
  33. HDM2 ubiquitin ligase 1 item
  34. PC-PLC 2item
  35. AAT 1 item
  36. Histone Acetyltransferases (HATs) 1 item
  37. Tyrosinases 1 item
  38. HSP70 1 item
  39. Ubiquitin E3 Ligases 1 item
  40. MDMX 1 item
  41. p21 1 item
  42. DHFR 1 item
  43. GARFT 1 item
  44. PKD 1 item
  45. MCL1 1 item
  46. Bcl-w 1 item
  47. Bax 1 item
  48. NS3/4a Proteases 1 item
Reported Experiments
  1. Animal Experiments 57item
  2. Cell Experiments 48item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Adrenocortical Carcinoma 1 item
  3. Autoimmune Diseases 1 item
  4. Breast Cancer 5item
  5. Cancer 39item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Chronic Myeloproliferative Disorders 1 item
  8. Colon Cancer 3item
  9. Colorectal Cancer 2item
  10. Glioblastoma 4item
  11. HCV 1 item
  12. Hepatocellular Carcinoma 1 item
  13. Inflammatory Diseases 1 item
  14. Lung Cancer 2item
  15. Lymphoma 2item
  16. Melanoma 1 item
  17. Multiple Myeloma 2item
  18. Myelofibrosis 1 item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Cancer 3item
  21. Ovarian Cancer 1 item
  22. Pancreatic Cancer 3item
  23. Prostate Cancer 5item
  24. Pulmonary Fibrosis 1 item
  25. Rheumatoid Arthritis 1 item
  26. Soft Tissue Sarcoma 1 item
  27. Testicular Cancer 1 item