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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor racemic'

Search results for: 'p53 and mdm2 proteins interaction inhibitor racemic'

Items 241-250 of 351

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  1. JNJ-7706621
    A4115 JNJ-7706621
     1 Citation
    Target: Cyclin-Dependent Kinases|Aurora Kinases
    Summary: Potent CDK/Aurora kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥19.7 mg/mL
  2. Cucurbitacin I
    A4512 Cucurbitacin I
    Target: STAT|JAK
    Summary: STAT3/JAK2 signaling inhibitor
      ≥22.45 mg/mL
  3. PHA-680632
    A4122 PHA-680632
    Target: Aurora Kinases|PLK|FGFR
    Summary: Aurora kinase inhibitor,novel and potent
      ≥50.2 mg/mL
  4. SNS-314 Mesylate
    A4121 SNS-314 Mesylate
    Target: Aurora Kinases
    Summary: Aurora A/B/C kinases inhibitor, potent and selective
      ≥26.35 mg/mL
  5. AR-42 (OSU-HDAC42)
    A4104 AR-42 (OSU-HDAC42)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,novel and potent
      insoluble in EtOH; insoluble in H2O; ≥15.62 mg/mL
  6. CYT387
    A4143 CYT387
     1 Citation
    Summary: JAK-1/-2 inhibitor,ATP competitive
      insoluble in EtOH; insoluble in H2O; ≥20.7 mg/mL
  7. TCS PIM-1 1
    A4521 TCS PIM-1 1
    Summary: Pim-1 kinase inhibitor,ATP-competitve
      insoluble in H2O; insoluble in EtOH; ≥12.8 mg/mL
  8. BMN-673 8R,9S
    A3246 BMN-673 8R,9S
     1 Citation
    Summary: Inactive form of BMN 673, used as negative control
      ≥38 mg/mL
  9. Hesperadin
    A4118 Hesperadin
     1 Citation
    Target: Aurora Kinases
    Summary: Aurora B kinase inhibitor
      ≥25.85 mg/mL
  10. R8-T198wt
    A4520 R8-T198wt
    Summary: Pim-1 kinase inhibitor
      Soluble to 2 mg/mL

Items 241-250 of 351

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  1. Category Chromatin/Epigenetics Remove This Item
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Category
  1. Bromodomain 34item
  2. Aurora Kinase 30item
  3. DNA Methyltransferase 6item
  4. HDAC 56item
  5. Histone Acetyltransferases 15item
  6. Histone Demethylases 22item
  7. Histone Methyltransferase 43item
  8. HIF 11item
  9. JAK 41item
  10. MBT Domains 1 item
  11. PARP 31item
  12. Pim 8item
  13. Protein Ser/Thr Phosphatases 31item
  14. RNA Polymerase 3item
  15. Sirtuin 15item
  16. Sphingosine Kinase-2 1 item
  17. Polycomb repressive complex 1 item
  18. SUMOylation 2item
  19. PAD 1 item
Specificity
  1. Selective 105item
Reversibility
  1. Reversible 7item
  2. Irreversible 2item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 33item
  3. PI3K 1 item
  4. Aurora Kinases 21item
  5. EZH2 3item
  6. Bromodomains 8item
  7. FLT3 5item
  8. PLK 1 item
  9. VEGFR 3item
  10. RET 1 item
  11. Hydrolase 1 item
  12. MEK 1 item
  13. DOT1L 3item
  14. FGFR 2item
  15. Nrf2 1 item
  16. Pim 3item
  17. Sir2-like Family Deacetylases (Sirtuins) 3item
  18. PP1 1 item
  19. PP2A 1 item
  20. Src 4item
  21. Trk Receptors 1 item
  22. STAT 2item
  23. EGFR 2item
  24. Hypoxia Inducible Factors (HIFs) 2item
  25. Tankyrases 1 item
  26. JAK 20item
  27. p300 1 item
  28. Syk 1 item
  29. EZH1 1 item
  30. TNKS 1 item
  31. Topoisomerases 1 item
  32. ErbB 1 item
  33. DNA Methyltransferases 3item
  34. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  35. SMYD2 1 item
  36. CREBBP 2item
  37. EP300 2item
  38. LRRK2 1 item
  39. PARP 8item
  40. ALK 1 item
  41. Bromodomain and Extra-Terminal motif (BET) 1 item
  42. phosphatases 1 item
  43. NAT10 1 item
  44. G9a 2item
  45. Hck 1 item
  46. SETD7 1 item
  47. MNK 1 item
  48. AChE 1 item
  49. Catechol O-Methyltransferase (COMT) 1 item
  50. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  51. Protein Arginine Methyltransferases 1 item
  52. Cytidine deaminases 1 item
  53. PP4 1 item
  54. c-RET 1 item
  55. VEGFR3/FLT4 1 item
  56. NTRK1/TRKA 1 item
  57. CSF-1R/c-Fms 1 item
  58. PTP 1 item
  59. Protein polybromo-1 1 item
  60. SMARCA4 1 item
  61. SMARCA2 1 item
  62. p53 1 item
  63. HDAC 2item
  64. KDM 2item
  65. Histone Acetyltransferases (HATs) 2item
  66. Trx 1 item
  67. HIF-PH 1 item
  68. L3MBTL 1 item
  69. TYK2 2item
  70. MUSK 1 item
  71. MAP3K 1 item
  72. Lck 1 item
  73. p21 1 item
  74. PHF 1 item
  75. FGR 1 item
  76. YES 1 item
  77. Fyn 1 item
  78. ARG 1 item
  79. LSD 1 item
  80. PRMT 1 item
  81. GLP 1 item
  82. SK 1 item
  83. Sirtuin 1 item
Reported Experiments
  1. Animal Experiments 117item
  2. Cell Experiments 97item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 8item
  3. Bladder Cancer 2item
  4. Bladder Carcinoma 1 item
  5. Breast Cancer 19item
  6. Cancer 83item
  7. Castration-resistant Prostate Cancer 1 item
  8. Cervical Cancer 2item
  9. Chronic Lymphocytic Leukemia 1 item
  10. Colon Cancer 11item
  11. Colon Carcinoma 1 item
  12. Colorectal Cancer 5item
  13. Diabetes 1 item
  14. Diffuse Large B-cell Lymphoma 1 item
  15. Dyskinesia 1 item
  16. Epilepsy 1 item
  17. Friedreich's Ataxia 1 item
  18. Glioblastoma 2item
  19. Glioma 2item
  20. Hepatic Cancer 1 item
  21. Hepatocellular Carcinoma 1 item
  22. HIV 2item
  23. HIV Infections 2item
  24. Immunological Diseases 1 item
  25. Inflammatory Bowel Disease 1 item
  26. Inflammatory Diseases 3item
  27. Leukemia 7item
  28. Lung Cancer 6item
  29. Lymphoma 6item
  30. Melanoma 5item
  31. Mixed Lineage Leukemia 3item
  32. Multiple Myeloma 5item
  33. Myelofibrosis 1 item
  34. Myeloma 1 item
  35. Neuroblastoma 2item
  36. Neuronal Protection 1 item
  37. Non-small Cell Lung Cancer 5item
  38. Ovarian Cancer 5item
  39. Pancreatic Cancer 4item
  40. Prostate Cancer 12item
  41. Psoriasis 1 item
  42. Renal Cancer 1 item
  43. Renal Cell Carcinoma 2item
  44. Rheumatoid Arthritis 3item
  45. Thyroid Cancer 1 item