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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor racemic'

Search results for: 'p53 and mdm2 proteins interaction inhibitor racemic'

Items 141-150 of 331

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  1. AGI-5198
    A4339 AGI-5198
     1 Citation
    Summary: IDH1 inhibitor against R132 mutant,selective and cell-permeable
      ≥23.15 mg/mL
  2. PF-04620110
    A4384 PF-04620110
    Summary: DGAT-1 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥16.9 mg/mL
  3. Canagliflozin
    A8333 Canagliflozin
     1 Citation
    Target: SGLT
    Summary: SGLT2 inhibitor,potent and selective
      ≥22.25 mg/mL
  4. Rivaroxaban
    A4338 Rivaroxaban
    Target: Factor Xa
    Summary: Factor Xa inhibitor
      insoluble in H2O; insoluble in EtOH; ≥13.9 mg/mL
  5. PF-3845
    A4374 PF-3845
     1 Citation
    Target: FAAH
    Summary: FAAH ihibitor,highly potent and selective
      Soluble in DMSO
  6. Pimobendan
    A4340 Pimobendan
    Target: Phosphodiesterases (PDEs)
    Summary: Selective PDE3 inhibitor.Ca2+ channel sensitizer
      insoluble in H2O; ≥16.2 mg/mL
  7. Sildenafil Citrate
    A4321 Sildenafil Citrate
    Target: Phosphodiesterases (PDEs)
    Summary: Treat erectile dysfunction and PAH
      ≥25.35 mg/mL
  8. Posaconazole
    A1718 Posaconazole
    Target: Cytochrome P450 (CYP450)|sterol demethylase
    Summary: Sterol C14ɑ demethylase inhibitor
      ≥35.04 mg/mL
  9. CPI-613
    A4333 CPI-613
     1 Citation
    Target: Pyruvate dehydrogenases (PDH)
    Summary: PDH/α-KGDH inhibitor
      insoluble in H2O; ≥19.45 mg/mL
  10. PF-4981517
    A4311 PF-4981517
    Summary: CYP3A4 inhibitor,potent and selective
      Soluble in DMSO

Items 141-150 of 331

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  1. PPAR 2item
  2. 5-alpha Reductase 3item
  3. 5-Lipoxygenase 10item
  4. Adenosine Deaminase 2item
  5. Aminopeptidase 1 item
  6. C14ɑ demethylase 2item
  7. Carbonic Anhydrase 7item
  8. CETP 4item
  9. Cholesterol absorption 1 item
  10. CPT1 2item
  11. CYP3A/CYP450 12item
  12. Dehydrogenase 31item
  13. DHFR 3item
  14. DGAT 6item
  15. Dopamine β-hydroxylase 5item
  16. Enolase 1 item
  17. FAAH 19item
  18. Factor Xa 3item
  19. Ferroptosis 3item
  20. HLE 1 item
  21. HMG-CoA Reductase 13item
  22. HSP 23item
  23. IDO 7item
  24. KRAS-PDEδ 2item
  25. Lipid Metabolism 7item
  26. MAO 6item
  27. Neuronal Metabolism 3item
  28. Oxidative Phosphorylation 1 item
  29. P450 13item
  30. PDE 52item
  31. Phospholipase 28item
  32. Procollagen C Proteinase 1 item
  33. SCD 3item
  34. SGLT 7item
  35. TPH 4item
  36. Transferase 20item
  37. Transaminase 1 item
  38. monooxygenase 1 item
  39. aldehyde dehydrogenase 1 item
  40. Squalene synthase 1 item
  41. Hydrolase 9item
  42. ornithine decarboxylase 1 item
  43. phosphatases 5item
  44. MGL 1 item
  45. Galactosidase 1 item
  46. 12-Lipoxygenase 1 item
  47. Lipase inhibitor 1 item
Specificity
  1. Selective 62item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 1 item
  2. Irreversible 3item
Target
  1. Acyl coenzyme A: cholesterol acyltransferases 1 item
  2. Factor Xa 1 item
  3. Phosphodiesterases (PDEs) 16item
  4. Thymidylate Synthase 1 item
  5. 3-phosphoglycerate dehydrogenase 1 item
  6. Kynurenine-3-monooxygenase 1 item
  7. Aminopeptidases 1 item
  8. Stearoyl-CoA 9-desaturase (SCD-1) 2item
  9. HSP90 9item
  10. Cytochrome P450 (CYP450) 6item
  11. Ferroptosis 1 item
  12. HMG-CoA Reductases 6item
  13. SGLT 1 item
  14. DGAT 2item
  15. Pyruvate dehydrogenases (PDH) 1 item
  16. CETP 2item
  17. Lactate Dehydrogenases (LDH) 3item
  18. Fatty-acid-binding proteins (FABPs) 1 item
  19. IDH2 1 item
  20. Nampt 1 item
  21. Carbonic Anhydrases 3item
  22. Aldehyde Dehydrogenases 1 item
  23. Phospholipases 1 item
  24. Catechol O-Methyltransferase (COMT) 1 item
  25. Hydroxylases 1 item
  26. FPTase 1 item
  27. Tryptophan hydroxylases (TPH) 2item
  28. sodium channel 1 item
  29. Ftase 1 item
  30. PC-PLC 1 item
  31. HMGCR 1 item
  32. adrenergic receptor 1 item
  33. sterol demethylase 1 item
  34. GAPDH 1 item
  35. complex I of the mitochondrial electron transport chain 1 item
  36. potassium channel 1 item
  37. calcium channel 1 item
  38. FAAH 1 item
  39. carnitine reabsorption 1 item
  40. 5-alpha Reductases 1 item
  41. DHFR 1 item
  42. GARFT 1 item
  43. glutathione peroxidase 4 1 item
  44. S-adenosylhomocysteine hydrolase 1 item
  45. IDO 1 item
  46. Tph 1 item
  47. epoxide hydrolase 1 item
  48. Cholesterol absorption 1 item
  49. Glycogen Phosphorylases 1 item
Reported Experiments
  1. Animal Experiments 90item
  2. Cell Experiments 74item
Related Disease
  1. Acne 1 item
  2. Acute Kidney Injury 1 item
  3. Acute Myelogenous Leukemia 1 item
  4. Acute Myeloid Leukemia 2item
  5. Bladder Cancer 1 item
  6. Bladder Carcinoma 1 item
  7. Brain Injuries Studies 1 item
  8. Breast Cancer 8item
  9. Cancer 32item
  10. Chronic Lymphocytic Leukemia 1 item
  11. Cocaine-Related Disorders 2item
  12. Colon Cancer 1 item
  13. Diabetes 2item
  14. Dyslipidemia 1 item
  15. Epilepsy 2item
  16. Erectile Dysfunction 4item
  17. Fungi 1 item
  18. Glioblastoma 1 item
  19. Glioma 1 item
  20. Hepatic Cancer 1 item
  21. HIV Infections 1 item
  22. Hypercholesterolemia 3item
  23. Inflammation 1 item
  24. Inflammatory Diseases 1 item
  25. Kidney Injury Studies 1 item
  26. Leukemia 1 item
  27. Lung Cancer 3item
  28. Lymphoma 1 item
  29. Melanoma 7item
  30. Multiple Myeloma 2item
  31. Neuroblastoma 2item
  32. Neurocognitive Disorders 1 item
  33. Non-small Cell Lung Cancer 2item
  34. Obsessive-Compulsive Disorder 1 item
  35. Osteoporosis 1 item
  36. Pancreatic Cancer 2item
  37. Pancreatic Carcinoma 1 item
  38. Prostate Cancer 7item
  39. Psoriasis 2item
  40. Psoriasis Vulgaris 1 item
  41. Pulmonary Arterial Hypertension 1 item
  42. Rheumatoid Arthritis 1 item
  43. Schizophrenia 2item
  44. Type 2 Diabetes 2item