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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor racemic'

Search results for: 'p53 and mdm2 proteins interaction inhibitor racemic'

Items 1-10 of 394

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  1. Nutlin-3
    A4228 Nutlin-3
    Target: MDM2
    Summary: MDM2 antagonist,inhibits MDM2-p53 interaction
      ≥58.2 mg/mL
  2. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  3. AMG232
    A8804 AMG232
     2 Citation
    Target: p53-MDM2 interaction
    Summary: p53-MDM2 inhibitor, novel
      Soluble in DMSO
  4. AKT inhibitor VIII
    A3149 AKT inhibitor VIII
     2 Citation
    Target: Akt
    Summary: Allosteric Akt kinase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL
  5. GSK126
    A3446 GSK126
     5 Citation
    Target: EZH2
    Summary: EZH2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.38 mg/mL
  6. NVP-BEP800
    A4064 NVP-BEP800
    Target: HSP90
    Summary: Oral Hsp90β inhibitor, novel, fully synthetic
  7. PF-04929113 (SNX-5422)
    A4065 PF-04929113 (SNX-5422)
    Target: HSP90
    Summary: Hsp90 inhibitor,potent and selective
      ≥23.85 mg/mL
  8. Marimastat
    A4049 Marimastat
     1 Citation
    Target: MMP
    Summary: MMPs inhibitor,board spectrum
      ≥2.8 mg/mL
  9. CUDC-907
    A4097 CUDC-907
    Target: Histone Deacetylases (HDACs)|PI3K
    Summary: Potent PI3K/HDAC inhibitor
      ≥25.45 mg/mL
  10. Tariquidar
    A8208 Tariquidar
     2 Citation
    Target: P-glycoprotein (P-gp)
    Summary: P-glycoprotein inhibitor,potent and non-competitive
      insoluble in H2O; insoluble in EtOH; ≥16.17 mg/mL

Items 1-10 of 394

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  1. Signaling Pathways 388item
  2. Lab Reagents 1 item
Reversibility
  1. Reversible 21item
  2. Irreversible 13item
Target
  1. Caspases 2item
  2. Cyclin-Dependent Kinases 17item
  3. Proteasome 8item
  4. Cathepsins 2item
  5. Histone Deacetylases (HDACs) 18item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 5item
  8. Bcl-2 4item
  9. PI3K 19item
  10. CXCR 2item
  11. Raf 8item
  12. Aurora Kinases 9item
  13. Bcl-xl 2item
  14. CSF-1R 2item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. MDM2 2item
  18. EZH2 3item
  19. mTOR 10item
  20. Bromodomains 3item
  21. MMP 2item
  22. Thymidine Phosphorylases 1 item
  23. Androgen Receptors 2item
  24. DT-diaphorases 1 item
  25. FLT3 6item
  26. GSK-3 4item
  27. P-glycoprotein (P-gp) 5item
  28. PLK 6item
  29. Chk 5item
  30. Eph Receptors 2item
  31. VEGFR 22item
  32. PDGFR 14item
  33. c-Kit 6item
  34. RET 3item
  35. Bromodomain-containing proteins(BRDs) 1 item
  36. Phosphodiesterases (PDEs) 2item
  37. Mcl-1 4item
  38. Thymidylate Synthase 2item
  39. p38 3item
  40. JNK 1 item
  41. SGK 1 item
  42. Bcr-Abl 5item
  43. MEK 11item
  44. PORCN 1 item
  45. DOT1L 3item
  46. FGFR 8item
  47. Insulin-like growth factor receptors(IGFRs) 1 item
  48. Pim 3item
  49. Sir2-like Family Deacetylases (Sirtuins) 2item
  50. Deubiquitinating enzymes (DUBs) 2item
  51. PP1 1 item
  52. PP2A 1 item
  53. Smoothened 4item
  54. MET 7item
  55. Src 4item
  56. Trk Receptors 4item
  57. Integrins 1 item
  58. Aminopeptidases 1 item
  59. STAT 6item
  60. Microtubules/Tubulins 3item
  61. EGFR 13item
  62. Hedgehog 1 item
  63. PAK 3item
  64. Hypoxia Inducible Factors (HIFs) 2item
  65. FAK 5item
  66. BMP and Other Activin Receptors 2item
  67. JAK 7item
  68. p300 1 item
  69. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  70. Syk 4item
  71. EZH1 1 item
  72. DNA-PK 4item
  73. HSP90 10item
  74. Gutathione S-transferase 1 item
  75. Notch 1 item
  76. TNKS 1 item
  77. Topoisomerases 7item
  78. Cytochrome P450 (CYP450) 4item
  79. Ksp 1 item
  80. ErbB 2item
  81. DNA Methyltransferases 2item
  82. Survivin 1 item
  83. ERK 3item
  84. HMG-CoA Reductases 2item
  85. c-MET 7item
  86. BMI-1 1 item
  87. PKC 4item
  88. Calpains 2item
  89. Ubiquitin-specific proteases 1 item
  90. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  91. CREBBP 1 item
  92. EP300 1 item
  93. Lyn 1 item
  94. RAD51 1 item
  95. HER2 1 item
  96. Pyk2 3item
  97. USP 1 item
  98. 5-HT2 Receptors 1 item
  99. Insulin and Insulin-like Receptors 1 item
  100. PARP 1 item
  101. ALK 4item
  102. ROS1 2item
  103. Sphingosine kinases (SphKs) 1 item
  104. Monocarboxylate transporters (MCTs) 1 item
  105. Dehydrogenase 1 item
  106. D1 and D5 Receptors 1 item
  107. D2 Receptors 1 item
  108. D3 Receptors 1 item
  109. MELK 1 item
  110. Insulin-like growth factors (IGFs) 1 item
  111. CSF1R 1 item
  112. Bromodomain and Extra-Terminal motif (BET) 1 item
  113. MK2 1 item
  114. Angiotensin-Converting Enzymes (ACEs) 1 item
  115. Tie-2 3item
  116. RSK 1 item
  117. p70 S6K 1 item
  118. Autophagy 2item
  119. ATM/ATR 4item
  120. COX 2item
  121. Farnesyl Diphosphate Synthases 1 item
  122. CK2 1 item
  123. HIPK2 1 item
  124. HIPK3 1 item
  125. HIV Integrases 1 item
  126. PRAK 1 item
  127. MAPKAP-K2 1 item
  128. Guanine nucleotide exchange factors (GEFs) 1 item
  129. 20S proteasomal chymotrypsin 1 item
  130. Geranylgeranyltransferase I 1 item
  131. Farnesyltransferase 1 item
  132. Nampt 2item
  133. eIF4F 1 item
  134. Cdc42 1 item
  135. Glutaminases 1 item
  136. Carbonic Anhydrases 1 item
  137. Ron 1 item
  138. BLM 1 item
  139. Aldehyde Dehydrogenases 1 item
  140. Synthases/Synthetases 1 item
  141. P110 1 item
  142. Hck 1 item
  143. Inositol-requiring enzyme 1 (IRE1) 1 item
  144. Norepinephrine transporter 1 item
  145. 5-HT Transporters 1 item
  146. FoxM1 1 item
  147. Histone Demethylases 1 item
  148. HIV-1 reverse transcriptase 1 item
  149. Insulin Receptors 1 item
  150. IRG-1R 1 item
  151. cAMP 1 item
  152. Sulfonylurea receptors 1 item
  153. eEF-2 1 item
  154. Cdc7 1 item
  155. CMV 1 item
  156. ZAP-70 1 item
  157. Catechol O-Methyltransferase (COMT) 1 item
  158. fibrinolysis 1 item
  159. D4 Receptors 1 item
  160. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  161. Flk-1 1 item
  162. Papains 1 item
  163. Protein Arginine Methyltransferases 1 item
  164. NAE 2item
  165. Ubiquitin-activating Enzyme E1 1 item
  166. SUMOylation 1 item
  167. Cytidine deaminases 1 item
  168. angiogenesis 1 item
  169. DPP-4 1 item
  170. PP4 1 item
  171. TAM kinase 1 item
  172. p53-MDM2 interaction 1 item
  173. nuclear export 1 item
  174. CRM1 1 item
  175. AXL 1 item
  176. human lyase 1 item
  177. Ub-conjugating enzyme (E2) complex 1 item
  178. MCL1 1 item
  179. Bcl-w 1 item
  180. tropomyosin receptor kinase 1 item
  181. LSD 1 item
  182. SK 1 item
  183. IDO 1 item
  184. Substance P/NK1 Receptor 1 item