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Search results for: 'p53 and mdm2 proteins interaction inhibitor racemic'

Search results for: 'p53 and mdm2 proteins interaction inhibitor racemic'

A8307 Crenolanib (CP-868596)

1 Citation

Target: FLT3|PDGFR

Summary: PDGFR-β inhibitor,potent and selective

≥22.2 mg/mL
B3277 AMG 925

Target: Cyclin-Dependent Kinases|FLT3

Summary: FLT3/CDK4 inhibitor,potent and selective

insoluble in DMSO; insoluble in H2O; insoluble in EtOH
B1404 DCC-2036 (Rebastinib)

Target: FLT3|Bcr-Abl|Tie-2|KDR

Summary: Bcr-Abl inhibitor

≥27.7 mg/mL
A4147 LY2784544

Target: Aurora Kinases|FLT3|VEGFR|FGFR|Trk Receptors|JAK|ALK|TYK2|MUSK|MAP3K

Summary: JAK2 inhibitor,highly potent and selective

≥23.5 mg/mL
A8889 G-749

Target: Aurora Kinases|FLT3|c-RET

Summary: FLT3 inhibitor

≥26.05 mg/mL
A2168 Dovitinib (TKI-258, CHIR-258)

2 Citation

Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR

Summary: Multitargeted RTK inhibitor

insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
A8476 MK-2461

Target: FLT3|PDGFR|MET|Ron

Summary: C-Met (WT/mutants) inhibitor

≥24.8 mg/mL
B5832 Altiratinib

1 Citation

Target: FLT3|VEGFR|Trk Receptors|c-MET|Tie-2

Summary: c-MET/TIE-2/VEGFR inhibitor

≥21.55 mg/mL
A4125 CYC116

Target: Aurora Kinases|FLT3|VEGFR

Summary: Potent Aurora A/B inhibitor

insoluble in EtOH; insoluble in H2O; ≥18.4 mg/mL
A4130 ENMD-2076

Target: Aurora Kinases|FLT3|RET|Src|VEGFR3/FLT4|NTRK1/TRKA|CSF-1R/c-Fms

Summary: Selective Aurora A/Flt3 inhibitor

insoluble in H2O; ≥18.75 mg/mL