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  • Search results for: 'p53 and mdm2 proteins interaction inhibitor racemic'

Search results for: 'p53 and mdm2 proteins interaction inhibitor racemic'

Items 1-10 of 696

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  1. Nutlin-3
    A4228 Nutlin-3
    Target: MDM2
    Summary: MDM2 antagonist,inhibits MDM2-p53 interaction
      ≥58.2 mg/mL
  2. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  3. IKK-2 inhibitor VIII
    A3485 IKK-2 inhibitor VIII
    Summary: IKK-2 inhibitor,potent and selective
      Soluble in DMSO
  4. AMG232
    A8804 AMG232
     2 Citation
    Target: p53-MDM2 interaction
    Summary: p53-MDM2 inhibitor, novel
      Soluble in DMSO
  5. Calpain Inhibitor I, ALLN
    A2602 Calpain Inhibitor I, ALLN
     2 Citation
    Target: Cathepsins|Calpains
    Summary: Calpain I/II/ B/L inhibitor
  6. Tie2 kinase inhibitor
    A5979 Tie2 kinase inhibitor
    Target: Tie-2
    Summary: Tie-2(Tie2 ) inhibitor
      ≥22 mg/mL
  7. AKT inhibitor VIII
    A3149 AKT inhibitor VIII
     2 Citation
    Target: Akt
    Summary: Allosteric Akt kinase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL
  8. Tankyrase Inhibitors (TNKS) 49
    A8601 Tankyrase Inhibitors (TNKS) 49
    Target: Tankyrases
    Summary: Tankyrase inhibitor
      ≥22.45 mg/mL
  9. GSK126
    A3446 GSK126
     5 Citation
    Target: EZH2
    Summary: EZH2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.38 mg/mL
  10. Cathepsin S inhibitor
    A3284 Cathepsin S inhibitor
     1 Citation
    Target: Cathepsins
    Summary: Blocks MHCII antigen presentation
      ≥24.25 mg/mL

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  1. Signaling Pathways 676item
  2. Natural Products 2item
  3. Lab Reagents 2item
Reversibility
  1. Reversible 45item
  2. Irreversible 18item
Target
  1. Caspases 6item
  2. Cyclin-Dependent Kinases 20item
  3. Proteasome 11item
  4. Cathepsins 9item
  5. Histone Deacetylases (HDACs) 24item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 6item
  8. Bcl-2 5item
  9. PI3K 26item
  10. CXCR 4item
  11. Raf 10item
  12. Aurora Kinases 11item
  13. Bcl-xl 2item
  14. CSF-1R 2item
  15. Glycoproteins 1 item
  16. p97 1 item
  17. MDM2 2item
  18. EZH2 4item
  19. mTOR 14item
  20. Bromodomains 4item
  21. AP-1 1 item
  22. MMP 7item
  23. Thymidine Phosphorylases 1 item
  24. Androgen Receptors 3item
  25. Peptidylprolyl isomerases 1 item
  26. Acyl coenzyme A: cholesterol acyltransferases 1 item
  27. Myosin II ATPases 1 item
  28. DT-diaphorases 1 item
  29. MER 1 item
  30. FLT3 12item
  31. GSK-3 9item
  32. Factor Xa 3item
  33. P-glycoprotein (P-gp) 5item
  34. PLK 6item
  35. Chk 7item
  36. Eph Receptors 2item
  37. VEGFR 25item
  38. PDGFR 17item
  39. c-Kit 7item
  40. RET 3item
  41. Bromodomain-containing proteins(BRDs) 1 item
  42. Phosphodiesterases (PDEs) 10item
  43. Mcl-1 4item
  44. Hydrolase 1 item
  45. Thymidylate Synthase 2item
  46. p38 9item
  47. PKB 1 item
  48. JNK 3item
  49. SGK 1 item
  50. Bcr-Abl 8item
  51. Kynurenine-3-monooxygenase 1 item
  52. MEK 13item
  53. PORCN 1 item
  54. DOT1L 3item
  55. FGFR 9item
  56. Nrf2 1 item
  57. Insulin-like growth factor receptors(IGFRs) 1 item
  58. Pim 4item
  59. Sir2-like Family Deacetylases (Sirtuins) 2item
  60. Deubiquitinating enzymes (DUBs) 3item
  61. PP1 1 item
  62. PP2A 1 item
  63. Smoothened 4item
  64. Neuraminidases (NA) 1 item
  65. MET 7item
  66. Src 5item
  67. Trk Receptors 5item
  68. Integrins 1 item
  69. Aminopeptidases 2item
  70. STAT 6item
  71. ATP Citrate Lyases 1 item
  72. Microtubules/Tubulins 3item
  73. EGFR 14item
  74. Hedgehog 1 item
  75. ROCK 5item
  76. BTK 1 item
  77. RIP kinases 1 item
  78. Monocyte chemotactic proteins 1 item
  79. PAK 3item
  80. Hypoxia Inducible Factors (HIFs) 2item
  81. Tankyrases 1 item
  82. Inositol Phosphatases 1 item
  83. FAK 5item
  84. BMP and Other Activin Receptors 3item
  85. JAK 12item
  86. p300 1 item
  87. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  88. Syk 7item
  89. EZH1 2item
  90. DNA-PK 6item
  91. HSP90 10item
  92. AMPK 2item
  93. Gutathione S-transferase 1 item
  94. PDHK 1 item
  95. Angiotensin AT2 Receptors 1 item
  96. Notch 1 item
  97. S-nitrosoglutathione reductase 1 item
  98. CFTR 4item
  99. TNKS 1 item
  100. Topoisomerases 7item
  101. Cytochrome P450 (CYP450) 5item
  102. thrombin 1 item
  103. Ksp 1 item
  104. Renin 1 item
  105. Influenza viruses 1 item
  106. ErbB 2item
  107. S6 kinases 1 item
  108. Toll-like receptors (TLRs) 2item
  109. Adenosine Kinases 2item
  110. DNA Methyltransferases 2item
  111. Survivin 1 item
  112. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  113. ERK 5item
  114. HMG-CoA Reductases 5item
  115. c-MET 8item
  116. BMI-1 1 item
  117. PKC 5item
  118. Calpains 5item
  119. Ubiquitin-specific proteases 1 item
  120. HCV Proteases 3item
  121. Ca2 /calmodulin-dependent protein kinases (CaMKs) 6item
  122. MLK3 1 item
  123. O-GlcNAcase 1 item
  124. CREBBP 1 item
  125. EP300 1 item
  126. Lyn 1 item
  127. SGLT 1 item
  128. RAD51 1 item
  129. Trypsins 1 item
  130. HER2 2item
  131. Pyk2 3item
  132. USP 1 item
  133. 5-HT2 Receptors 4item
  134. LRRK2 4item
  135. Voltage-gated Calcium Channels (CaV) 1 item
  136. DGAT 2item
  137. Insulin and Insulin-like Receptors 3item
  138. PARP 4item
  139. CB1 Receptors 1 item
  140. Melanocortin (MC) Receptors 1 item
  141. Pyruvate dehydrogenases (PDH) 1 item
  142. ALK 5item
  143. ROS1 2item
  144. Sphingosine kinases (SphKs) 2item
  145. Trypsin 1 item
  146. Chymotrypsin 1 item
  147. Kallikrein 1 item
  148. Trypsinogen 1 item
  149. Monocarboxylate transporters (MCTs) 1 item
  150. CETP 2item
  151. Dehydrogenase 1 item
  152. Myosin light chain kinases (MLCKs) 1 item
  153. HIV-1 gp120 1 item
  154. D1 and D5 Receptors 1 item
  155. D2 Receptors 3item
  156. D3 Receptors 2item
  157. 5-HT1 Receptors 2item
  158. 5-HT7 Receptors 1 item
  159. MELK 1 item
  160. Serotonin reuptake 1 item
  161. Insulin-like growth factors (IGFs) 1 item
  162. CSF1R 1 item
  163. Bromodomain and Extra-Terminal motif (BET) 1 item
  164. Lactate Dehydrogenases (LDH) 1 item
  165. MK2 2item
  166. Fatty-acid-binding proteins (FABPs) 1 item
  167. Angiotensin-Converting Enzymes (ACEs) 4item
  168. Tie-2 4item
  169. RSK 2item
  170. p70 S6K 1 item
  171. Free Fatty Acid Receptors 1 item
  172. phosphatases 1 item
  173. Autophagy 2item
  174. ATM/ATR 5item
  175. COX 6item
  176. Farnesyl Diphosphate Synthases 1 item
  177. CK2 2item
  178. HIPK2 1 item
  179. HIPK3 1 item
  180. HIV Integrases 1 item
  181. Squalene epoxidases 2item
  182. PRAK 1 item
  183. MAPKAP-K2 1 item
  184. Delayed rectifier outward potassium current (IKr) 1 item
  185. GpIIb/IIIa receptor 1 item
  186. Guanine nucleotide exchange factors (GEFs) 1 item
  187. 20S proteasomal chymotrypsin 1 item
  188. Geranylgeranyltransferase I 1 item
  189. Farnesyltransferase 1 item
  190. Nampt 2item
  191. eIF4F 1 item
  192. Cdc42 1 item
  193. SRPK1 1 item
  194. P2X Receptors 1 item
  195. Glutaminases 1 item
  196. Carbonic Anhydrases 6item
  197. Ron 1 item
  198. G9a 1 item
  199. BLM 1 item
  200. HSV 1 item
  201. NADPH Oxidases 2item
  202. Calcium-activated chloride channels (CaCC) 1 item
  203. GPR35 1 item
  204. Aldehyde Dehydrogenases 1 item
  205. Synthases/Synthetases 2item
  206. MAGL 1 item
  207. Histamine H1 Receptors 2item
  208. Na /K ATPases 2item
  209. P110 1 item
  210. Hck 1 item
  211. Inositol-requiring enzyme 1 (IRE1) 2item
  212. Na /K /Cl- Symporters (NKCCs) 1 item
  213. GABAA Receptors 1 item
  214. Phospholipases 1 item
  215. Organic anion transporters (OATs) 1 item
  216. TRP Channel 1 item
  217. RNA Polymerases 1 item
  218. Norepinephrine transporter 1 item
  219. 5-HT Transporters 3item
  220. Xanthine oxidoreductases 1 item
  221. Dihydroorotate dehydrogenase 1 item
  222. FoxM1 1 item
  223. Histone Demethylases 1 item
  224. MNK 1 item
  225. NO Donors / Precursors 2item
  226. CB2 Receptors 1 item
  227. HIV-1 reverse transcriptase 1 item
  228. IL Receptors 2item
  229. CCL2 1 item
  230. Noradrenaline reuptake 1 item
  231. Norepinephrine transporters 1 item
  232. Calcium-Activated Potassium (KCa) Channels 1 item
  233. AChE 2item
  234. Insulin Receptors 1 item
  235. IRG-1R 1 item
  236. cAMP 1 item
  237. Sulfonylurea receptors 1 item
  238. Cdc2-like kinase (Clk) 1 item
  239. eEF-2 1 item
  240. Inward Rectifier Potassium (Kir) Channels 2item
  241. Cdc7 1 item
  242. CMV 1 item
  243. ZAP-70 1 item
  244. Catechol O-Methyltransferase (COMT) 2item
  245. fibrinolysis 1 item
  246. D4 Receptors 1 item
  247. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  248. HBV Proteases 1 item
  249. Flk-1 1 item
  250. Papains 1 item
  251. Protein Arginine Methyltransferases 1 item
  252. IMPDH 1 item
  253. Na /Ca2 Exchangers (NCXs) 1 item
  254. NAE 2item
  255. Ubiquitin-activating Enzyme E1 1 item
  256. SUMOylation 1 item
  257. ATGL 1 item
  258. BACE 1 item
  259. Cytidine deaminases 1 item
  260. GPR40 1 item
  261. angiogenesis 1 item
  262. Glucagon Receptors 1 item
  263. 15-PGDH 1 item
  264. DPP-4 4item
  265. PP4 1 item
  266. c-RET 1 item
  267. Nonstructural protein 5B (NS5B) 1 item
  268. p70 rsk 1 item
  269. FPTase 1 item
  270. ADAMs 1 item
  271. TAM kinase 1 item
  272. p53-MDM2 interaction 1 item
  273. nuclear export 1 item
  274. CRM1 1 item
  275. AXL 1 item
  276. Dipeptidyl-peptidase II 1 item
  277. HDAC 1 item
  278. c-Fms tyrosine kinase 1 item
  279. human lyase 1 item
  280. Ub-conjugating enzyme (E2) complex 1 item
  281. IKK 1 item
  282. MSK 1 item
  283. HCV polymerase 1 item
  284. Ftase 1 item
  285. PC-PLC 1 item
  286. Elastases 1 item
  287. F1 Fo-ATPase 1 item
  288. ITK 1 item
  289. NUAK 1 item
  290. DCLK2 1 item
  291. FAAH 1 item
  292. TYK2 1 item
  293. Aromatases 1 item
  294. PKD 1 item
  295. SHIP 1 item
  296. MCL1 1 item
  297. Bcl-w 1 item
  298. tropomyosin receptor kinase 1 item
  299. LSD 1 item
  300. PRMT 1 item
  301. GLP 1 item
  302. SK 1 item
  303. MST 1 item
  304. IDO 1 item
  305. Serotonin (5-HT) reuptake 1 item
  306. Androgen Receptor 1 item
  307. Substance P/NK1 Receptor 1 item
  308. gp120/CD4 1 item
  309. ATM 1 item
  310. Sirtuin 1 item
  311. NE 1 item
  312. PIKfyve 1 item
  313. Glycogen Phosphorylases 1 item
  314. MTH1 1 item
  315. Insulin Receptor 1 item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acne 1 item
  3. Acute Disseminated Candidiasis 1 item
  4. Acute Kidney Injury 1 item
  5. Acute Lung Injury 1 item
  6. Acute Myelogenous Leukemia 5item
  7. Acute Myeloid Leukemia 25item
  8. Acute Renal Failure 1 item
  9. Adrenocortical Carcinoma 4item
  10. Advanced Renal Cell Carcinoma 1 item
  11. Autoimmune Diseases 1 item
  12. Biliary Cancer 1 item
  13. Bladder Cancer 10item
  14. Bladder Carcinoma 4item
  15. Bladder Diseases 2item
  16. B-lymphoid Malignancies 1 item
  17. Brain Injuries Studies 3item
  18. Breast Cancer 111item
  19. Cancer 394item
  20. Candida Peritonitis 1 item
  21. Candidemia 1 item
  22. Castration-resistant Prostate Cancer 1 item
  23. Cervical Cancer 5item
  24. Cholangiocarcinoma 2item
  25. Chronic Lymphocytic Leukemia 8item
  26. Chronic Myeloproliferative Disorders 1 item
  27. Clear Cell Renal Cell Carcinoma 2item
  28. Cocaine-Related Disorders 2item
  29. Colon Cancer 40item
  30. Colon Carcinoma 7item
  31. Colorectal Cancer 40item
  32. Depression 2item
  33. Diabetes 6item
  34. Diffuse Large B-cell Lymphoma 1 item
  35. Dyskinesia 1 item
  36. Dyslipidemia 2item
  37. Epilepsy 2item
  38. Erectile Dysfunction 3item
  39. Friedreich's Ataxia 2item
  40. Fungal Infection 1 item
  41. Glioblastoma 30item
  42. Glioma 17item
  43. HCV 2item
  44. Heart Failure 1 item
  45. Hepatic Cancer 2item
  46. Hepatitis C 3item
  47. Hepatocellular Carcinoma 7item
  48. HIV 3item
  49. HIV Infections 8item
  50. Hypercholesterolemia 2item
  51. Immunological Diseases 1 item
  52. Inflammation 1 item
  53. Inflammatory Bowel Disease 1 item
  54. Inflammatory Diseases 13item
  55. Influenza 2item
  56. Kidney Injury Studies 1 item
  57. Leukemia 22item
  58. Liver Cancer 4item
  59. Lung Cancer 40item
  60. Lung Carcinoma 4item
  61. Lymphoma 28item
  62. Mantle Cell Lymphoma 2item
  63. Medulloblastoma 1 item
  64. Melanoma 30item
  65. Mixed Lineage Leukemia 3item
  66. Multiple Myeloma 21item
  67. Myelofibrosis 2item
  68. Myeloma 6item
  69. Neuroblastoma 13item
  70. Neurocognitive Disorders 1 item
  71. Neuronal Protection 1 item
  72. Non-small Cell Lung Cancer 25item
  73. Non-small Cell Lung Carcinoma 2item
  74. Obsessive-Compulsive Disorder 1 item
  75. Osteoporosis 2item
  76. Ovarian Cancer 33item
  77. Pancreatic Cancer 48item
  78. Pancreatic Carcinoma 3item
  79. Prostate Cancer 50item
  80. Psoriasis 4item
  81. Psoriasis Vulgaris 1 item
  82. Pulmonary Arterial Hypertension 2item
  83. Pulmonary Fibrosis 2item
  84. Renal Cancer 4item
  85. Renal Cell Carcinoma 8item
  86. Rheumatoid Arthritis 14item
  87. Sarcoma 1 item
  88. Schizophrenia 7item
  89. Sleep Disorders 2item
  90. Soft Tissue Sarcoma 1 item
  91. Squamous Cell Carcinoma 2item
  92. Testicular Cancer 2item
  93. Thyroid Cancer 6item
  94. Type 2 Diabetes 14item