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  • Search results for: 'pi3 kinase p110'

Search results for: 'pi3 kinase p110'

Items 71-80 of 195

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  1. ENMD-2076
    A4130 ENMD-2076
    Target: Aurora Kinases|FLT3|RET|Src|VEGFR3/FLT4|NTRK1/TRKA|CSF-1R/c-Fms
    Summary: Selective Aurora A/Flt3 inhibitor
      insoluble in H2O; ≥18.75 mg/mL
  2. AZD-5438
    A8326 AZD-5438
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK1/2/9 inhibitor
      insoluble in H2O; ≥18.55 mg/mL
  3. Lapatinib Ditosylate
    A3967 Lapatinib Ditosylate
    Target: EGFR|ErbB-2
    Summary: EGFR/HER2 inhibitor,potent and selective
      ≥24.3 mg/mL
  4. AC480 (BMS-599626)
    A2822 AC480 (BMS-599626)
    Target: EGFR
    Summary: HER1/2 inhibitor,selective and efficacious
      ≥28.35 mg/mL
  5. Dacomitinib (PF299804, PF299)
    A8319 Dacomitinib (PF299804, PF299)
    Target: ErbB
    Summary: HER inhibitor
      ≥23.5 mg/mL
  6. CUDC-101
    A4092 CUDC-101
     1 Citation
    Target: Histone Deacetylases (HDACs)|EGFR|ErbB
    Summary: Multitargeted HDAC inhibitor
      ≥21.7 mg/mL
  7. KU-0060648
    A1769 KU-0060648
     1 Citation
    Target: PI3K|DNA-PK
    Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
  8. Regorafenib
    A8236 Regorafenib
     4 Citation
    Target: Raf|VEGFR|PDGFR|c-Kit|RET
    Summary: Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1
      ≥25.04 mg/mL
  9. Nintedanib (BIBF 1120)
    A8252 Nintedanib (BIBF 1120)
     3 Citation
    Target: VEGFR|PDGFR|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
  10. PD 173074
    A8253 PD 173074
    Target: VEGFR|FGFR
    Summary: FGFR inhibitor
      ≥26.18 mg/mL

Items 71-80 of 195

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  1. Category Signaling Pathways Remove This Item
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Category
  1. Apoptosis 5item
  2. Chromatin/Epigenetics 24item
  3. MAPK Signaling 14item
  4. Tyrosine Kinase 79item
  5. DNA Damage/DNA Repair 6item
  6. PI3K/Akt/mTOR Signaling 24item
  7. Cell Cycle/Checkpoint 52item
  8. Ubiquitination/ Proteasome 3item
  9. JAK/STAT Signaling 21item
  10. TGF-β / Smad Signaling 16item
  11. GPCR/G protein 1 item
  12. Stem Cell 3item
  13. Others 5item
  14. Immunology/Inflammation 1 item
Specificity
  1. Selective 153item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 18item
  2. Irreversible 6item
Target
  1. Cyclin-Dependent Kinases 22item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 4item
  4. PI3K 11item
  5. Raf 9item
  6. Aurora Kinases 16item
  7. CSF-1R 4item
  8. mTOR 5item
  9. FLT3 7item
  10. GSK-3 4item
  11. PLK 5item
  12. Chk 4item
  13. Eph Receptors 3item
  14. VEGFR 27item
  15. PDGFR 17item
  16. c-Kit 9item
  17. RET 4item
  18. Bromodomain-containing proteins(BRDs) 1 item
  19. p38 3item
  20. JNK 1 item
  21. SGK 2item
  22. Bcr-Abl 6item
  23. MEK 2item
  24. FGFR 9item
  25. Pim 3item
  26. Ribosomal s6 kinases (RSK) 1 item
  27. MET 5item
  28. Src 8item
  29. Trk Receptors 1 item
  30. STAT 1 item
  31. EGFR 13item
  32. PAK 3item
  33. FAK 4item
  34. BMP and Other Activin Receptors 1 item
  35. JAK 7item
  36. Syk 3item
  37. DNA-PK 4item
  38. ErbB 4item
  39. ERK 2item
  40. c-MET 5item
  41. PKC 8item
  42. Ubiquitin-specific proteases 1 item
  43. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  44. Lyn 1 item
  45. HER2 1 item
  46. Pyk2 3item
  47. Insulin and Insulin-like Receptors 2item
  48. ALK 5item
  49. ROS1 1 item
  50. Sphingosine kinases (SphKs) 1 item
  51. PKG 2item
  52. PKA 4item
  53. Myosin light chain kinases (MLCKs) 1 item
  54. MELK 1 item
  55. Insulin-like growth factors (IGFs) 1 item
  56. MK2 1 item
  57. Tie-2 1 item
  58. RSK 1 item
  59. ATM/ATR 3item
  60. CK1 1 item
  61. Farnesyl Diphosphate Synthases 1 item
  62. CK2 1 item
  63. HIPK2 1 item
  64. HIPK3 1 item
  65. P110 1 item
  66. Hck 1 item
  67. MNK 1 item
  68. Insulin Receptors 1 item
  69. IRG-1R 1 item
  70. eEF-2 1 item
  71. Cdc7 1 item
  72. ZAP-70 1 item
  73. c-RET 2item
  74. p70 rsk 1 item
  75. VEGFR3/FLT4 1 item
  76. NTRK1/TRKA 1 item
  77. CSF-1R/c-Fms 1 item
  78. TAM kinase 1 item
  79. KDR 1 item
  80. AXL 1 item
  81. insulin 1 item
  82. ErbB-2 1 item
  83. PDK-1 1 item
  84. Prk 1 item
  85. Flk1 2item
  86. tropomyosin receptor kinase 1 item
  87. SK 1 item
  88. PPK 1 item
  89. c-Syk 1 item
  90. CDK1/CyclinB 1 item
  91. PIM1 kinase 1 item
  92. phospholipase A2 1 item
Reported Experiments
  1. Animal Experiments 182item
  2. Cell Experiments 120item