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  • Search results for: 'pi3 kinase p110'

Search results for: 'pi3 kinase p110'

Items 101-110 of 116

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  1. PF-477736
    B1437 PF-477736
    Target: Chk
    Summary: Chk1 inhibitor
      insoluble in EtOH; insoluble in H2O; ≥5.24 mg/mL
  2. NMS-1286937
    B4094 NMS-1286937
    Target: PLK
    Summary: PLK1 inhibitor, orally bioavailable
      insoluble in H2O; insoluble in EtOH; ≥13.33 mg/mL
  3. CVT-313
    A3336 CVT-313
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Cdk2 inhibitor
      ≥20 mg/mL
  4. ON123300
    B6192 ON123300
    Summary: multi-targeted kinase inhibitor,inhibits CDK4, Ark5, PDGFRβ, FGFR1, RET, and Fyn
      ≥21.5 mg/mL
  5. LEE011 hydrochloride
    B1083 LEE011 hydrochloride
    Summary: CDK inhibitor
      Soluble in DMSO
  6. LEE011 succinate
    B1084 LEE011 succinate
    Summary: CDK inhibitor
      Soluble in DMSO
  7. MK-8776 (SCH-900776)
    A8477 MK-8776 (SCH-900776)
    Target: Chk
    Summary: Chk1 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥18.8 mg/mL
  8. Ro 3306
    A8885 Ro 3306
     4 Citation
    Target: Cyclin-Dependent Kinases
    Summary: An ATP-competitive, potent CDK1 inhibitor
      insoluble in EtOH; insoluble in H2O; ≥4.39 mg/mL
  9. Ro3280
    A8681 Ro3280
    Target: PLK
    Summary: PLK1 inhibitor,potent and highly selective
      ≥27.2 mg/mL
  10. THZ1
    A8882 THZ1
     12 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Covalent CDK7 inhibitor,potent and selective
      ≥28.3 mg/mL

Items 101-110 of 116

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Category
  1. ATM/ATR 7item
  2. Aurora Kinase 27item
  3. Cdc7 2item
  4. Chk 9item
  5. Cyclin-Dependent Kinases 36item
  6. Haspin 1 item
  7. Kinesin 1 item
  8. Mps1 3item
  9. ROCK 8item
  10. Rho 3item
  11. PAK1 4item
  12. PAK4 1 item
  13. PERK 2item
  14. PLK 11item
  15. Wee1 1 item
Specificity
  1. Selective 54item
Reversibility
  1. Reversible 7item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 24item
  2. PI3K 2item
  3. Aurora Kinases 19item
  4. mTOR 1 item
  5. FLT3 5item
  6. GSK-3 1 item
  7. PLK 6item
  8. Chk 5item
  9. VEGFR 1 item
  10. PDGFR 1 item
  11. RET 1 item
  12. Bromodomain-containing proteins(BRDs) 1 item
  13. MEK 1 item
  14. FGFR 1 item
  15. Src 3item
  16. ROCK 6item
  17. PAK 3item
  18. JAK 1 item
  19. DNA-PK 1 item
  20. LRRK2 1 item
  21. Clk 1 item
  22. MK2 1 item
  23. ATM/ATR 4item
  24. Farnesyl Diphosphate Synthases 1 item
  25. Hck 1 item
  26. Cdc7 1 item
  27. VEGFR3/FLT4 1 item
  28. NTRK1/TRKA 1 item
  29. CSF-1R/c-Fms 1 item
  30. Histone Acetyltransferases (HATs) 1 item
  31. Lck 1 item
  32. FGR 1 item
  33. YES 1 item
  34. Fyn 1 item
  35. ARG 1 item
  36. Rho-kinase 1 item
  37. ATM 1 item
Reported Experiments
  1. Animal Experiments 57item
  2. Cell Experiments 45item
Related Disease
  1. Acute Myeloid Leukemia 7item
  2. B-lymphoid Malignancies 1 item
  3. Breast Cancer 11item
  4. Cancer 52item
  5. Cervical Cancer 1 item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Colon Cancer 9item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 5item
  10. Glioblastoma 2item
  11. Glioma 2item
  12. Leukemia 1 item
  13. Liver Cancer 1 item
  14. Lung Cancer 3item
  15. Lymphoma 3item
  16. Mantle Cell Lymphoma 1 item
  17. Melanoma 2item
  18. Multiple Myeloma 1 item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Carcinoma 1 item
  21. Ovarian Cancer 6item
  22. Pancreatic Cancer 7item
  23. Prostate Cancer 2item
  24. Renal Cell Carcinoma 1 item
  25. Thyroid Cancer 1 item