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Search results for: 'pi3 kinase p110'

Search results for: 'pi3 kinase p110'

B5859 Entrectinib

Target: Trk Receptors|ALK|ROS1

Summary: Orally active inhibitor of ALK kinase

≥28.05 mg/mL
A3018 Trametinib (GSK1120212)

7 Citation

Target: MEK

Summary: MEK1 and MEK2 inhibitor, potent and selective

insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
B1437 PF-477736

Target: Chk

Summary: Chk1 inhibitor

insoluble in EtOH; insoluble in H2O; ≥5.24 mg/mL
A3023 P005091

1 Citation

Target: Ubiquitin-specific proteases

Summary: Ubiquitin-specific protease 7 (USP7) inhibitor

insoluble in H2O; insoluble in EtOH; ≥17.4 mg/mL
A8681 Ro3280

Target: PLK

Summary: PLK1 inhibitor,potent and highly selective

≥27.2 mg/mL
A2168 Dovitinib (TKI-258, CHIR-258)

2 Citation

Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR

Summary: Multitargeted RTK inhibitor

insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
A8370 Axitinib (AG 013736)

1 Citation

Target: VEGFR|PDGFR|c-Kit

Summary: VEGFR1/ c-Kit inhibitor

insoluble in H2O; ≥19.3 mg/mL
B5835 AZD2932

Target: FLT3|VEGFR|PDGFR|c-Kit

Summary: inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit

Soluble in DMSO
A1632 SB202190 (FHPI)

5 Citation

Target: p38

Summary: P38 MAPK inhibitor