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  • Search results for: 'r pfi 2 hydrochloride'

Search results for: 'r pfi 2 hydrochloride'

Items 41-50 of 198

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  1. Afatinib (BIBW2992)
    A8247 Afatinib (BIBW2992)
     1 Citation
    Target: EGFR
    Summary: Irreversible EGFR/HER2 inhibitor
      ≥24.3 mg/mL
  2. Nutlin-3
    A4228 Nutlin-3
    Target: MDM2
    Summary: MDM2 antagonist,inhibits MDM2-p53 interaction
      ≥58.2 mg/mL
  3. ARP 100
    A4432 ARP 100
     1 Citation
    Target: MMP
    Summary: Selective MMP-2 inhibitor
      ≥36.4 mg/mL
  4. Entinostat (MS-275,SNDX-275)
    A8171 Entinostat (MS-275,SNDX-275)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1 and HDAC3 inhibitor
      insoluble in H2O; ≥18.8 mg/mL
  5. Pimasertib (AS-703026)
    A5573 Pimasertib (AS-703026)
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.55 mg/mL
  6. NH125
    A8814 NH125
     1 Citation
    Target: eEF-2
    Summary: Selective eEF-2 kinase inhibitor
      ≥25.9 mg/mL
  7. Gliotoxin
    A4443 Gliotoxin
     1 Citation
    Target: 20S proteasomal chymotrypsin|Geranylgeranyltransferase I|Farnesyltransferase
    Summary: 20S proteasome inhibitor
      Soluble in DMSO
  8. PRIMA-1
    A4483 PRIMA-1
    Target: p53
    Summary: BAX inhibitor
      ≥110.6 mg/mL
  9. NSC 3852
    A4496 NSC 3852
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in EtOH; insoluble in H2O; ≥7.35 mg/mL
  10. Pifithrin-μ
    A4482 Pifithrin-μ
     1 Citation
    Target: Autophagy|p53|HSP70
    Summary: Inhibitor of p53 binding and anti-apoptotic
      insoluble in H2O; ≥18.1 mg/mL

Items 41-50 of 198

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Category
  1. Signaling Pathways 192item
  2. Natural Products 2item
Specificity
  1. Selective 151item
Reversibility
  1. Reversible 15item
  2. Irreversible 6item
Target
  1. Caspases 2item
  2. Cyclin-Dependent Kinases 12item
  3. Proteasome 1 item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 10item
  6. Akt 5item
  7. Bcl-2 7item
  8. PI3K 5item
  9. CXCR 1 item
  10. Raf 6item
  11. Aurora Kinases 3item
  12. Bcl-xl 2item
  13. CSF-1R 1 item
  14. MDM2 2item
  15. EZH2 3item
  16. mTOR 6item
  17. Bromodomains 2item
  18. MMP 3item
  19. Thymidine Phosphorylases 1 item
  20. Androgen Receptors 1 item
  21. FLT3 3item
  22. GSK-3 1 item
  23. P-glycoprotein (P-gp) 1 item
  24. PLK 3item
  25. Chk 1 item
  26. Eph Receptors 2item
  27. VEGFR 23item
  28. PDGFR 8item
  29. c-Kit 5item
  30. RET 2item
  31. Phosphodiesterases (PDEs) 1 item
  32. Mcl-1 3item
  33. JNK 1 item
  34. Bcr-Abl 2item
  35. MEK 7item
  36. DOT1L 1 item
  37. FGFR 5item
  38. Deubiquitinating enzymes (DUBs) 1 item
  39. Smoothened 1 item
  40. MET 4item
  41. Src 1 item
  42. RARs 1 item
  43. Trk Receptors 1 item
  44. Aminopeptidases 2item
  45. STAT 1 item
  46. Microtubules/Tubulins 1 item
  47. Estrogen and Related Receptors 1 item
  48. EGFR 10item
  49. Hedgehog 1 item
  50. PAK 1 item
  51. FAK 3item
  52. BMP and Other Activin Receptors 1 item
  53. JAK 4item
  54. Syk 2item
  55. EZH1 1 item
  56. DNA-PK 2item
  57. HSP90 3item
  58. AMPK 1 item
  59. TNKS 1 item
  60. Cytochrome P450 (CYP450) 2item
  61. Ksp 1 item
  62. ErbB 2item
  63. DNA Methyltransferases 2item
  64. ERK 2item
  65. c-MET 3item
  66. PKC 4item
  67. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  68. SMYD2 1 item
  69. SGLT 1 item
  70. RAD51 1 item
  71. Pyk2 3item
  72. Insulin and Insulin-like Receptors 1 item
  73. PARP 2item
  74. Pyruvate dehydrogenases (PDH) 1 item
  75. ALK 1 item
  76. Dehydrogenase 1 item
  77. PKG 2item
  78. PKA 5item
  79. Myosin light chain kinases (MLCKs) 1 item
  80. AdipoR2 1 item
  81. Integrin-ligand interactions 1 item
  82. 5-HT3 Receptors 1 item
  83. Tie-2 2item
  84. RSK 1 item
  85. Autophagy 1 item
  86. COX 2item
  87. Folate Analogue 1 item
  88. Guanine nucleotide exchange factors (GEFs) 1 item
  89. 20S proteasomal chymotrypsin 1 item
  90. Geranylgeranyltransferase I 1 item
  91. Farnesyltransferase 1 item
  92. Nampt 2item
  93. eIF4F 1 item
  94. Glutaminases 1 item
  95. P110 1 item
  96. Hck 1 item
  97. Opioid receptors 1 item
  98. FoxM1 1 item
  99. Apoptosis Inducers 1 item
  100. MNK 1 item
  101. Glucocorticoid Receptors 1 item
  102. eEF-2 1 item
  103. CMV 1 item
  104. Hexokinases 1 item
  105. Flk-1 1 item
  106. Cytidine deaminases 1 item
  107. c-RET 1 item
  108. p70 rsk 1 item
  109. Microtubule/Tubulin 1 item
  110. NMPRTase 1 item
  111. Bfl-1 1 item
  112. p53-MDM2 interaction 1 item
  113. KDR 2item
  114. p53 3item
  115. HDAC 1 item
  116. HDM2 ubiquitin ligase 1 item
  117. DNA Alkylating 1 item
  118. ErbB-2 1 item
  119. PDK-1 1 item
  120. Prk 1 item
  121. HSP70 1 item
  122. Flk1 2item
  123. Bcl-w 1 item
  124. SK 1 item
  125. PPK 1 item
  126. c-Syk 1 item
  127. CDK1/CyclinB 1 item
  128. Bax 1 item
Reported Experiments
  1. Animal Experiments 185item
  2. Cell Experiments 129item