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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 201-210 of 1526

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  1. Nutlin-3
    A4228 Nutlin-3
    Target: MDM2
    Summary: MDM2 antagonist,inhibits MDM2-p53 interaction
      ≥58.2 mg/mL
  2. Embelin
    A8235 Embelin
    Summary: XIAP inhibitor,cell-permeable
  3. Ac-LEHD-AFC
    A4419 Ac-LEHD-AFC
    Summary: Fluorogenic caspase substrate
      ≥42.5 mg/mL
  4. Cyclophosphamide monohydrate
    A4232 Cyclophosphamide monohydrate
    Summary: alkylating, cytotoxic agent,antitumor activity
      ≥13.95 mg/mL
  5. Pemetrexed disodium hemipenta hydrate
    A3707 Pemetrexed disodium hemipenta hydrate
    Summary: Antifolate and antimetabolite agent
      ≥23.42 mg/mL
  6. 8-pCPT-2-O-Me-cAMP-AM
    B5737 8-pCPT-2-O-Me-cAMP-AM
    Summary: Epac activator
      Soluble in DMSO
  7. GDC-0152
    A4224 GDC-0152
     2 Citation
    Target: Inhibitor of apoptosis proteins (IAP)
    Summary: IAP antagonist,potent amd samll-molecule
      ≥24.95 mg/mL
  8. 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
    C5246 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
    Summary: nonpeptidic angiotensin II receptor antagonist
  9. (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride
    C6547 (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride
      ≥16.05 mg/mL
  10. JNJ-26854165 (Serdemetan)
    A4204 JNJ-26854165 (Serdemetan)
     1 Citation
    Target: p53|HDM2 ubiquitin ligase
    Summary: P53 activator, blocking Mdm2-p53 interaction
      insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL

Items 201-210 of 1526

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Category
  1. Proteases 86item
  2. Apoptosis 154item
  3. Chromatin/Epigenetics 122item
  4. Metabolism 78item
  5. MAPK Signaling 45item
  6. Tyrosine Kinase 133item
  7. DNA Damage/DNA Repair 55item
  8. PI3K/Akt/mTOR Signaling 45item
  9. Microbiology & Virology 53item
  10. Cell Cycle/Checkpoint 61item
  11. Ubiquitination/ Proteasome 22item
  12. JAK/STAT Signaling 47item
  13. TGF-β / Smad Signaling 28item
  14. Angiogenesis 21item
  15. GPCR/G protein 178item
  16. Stem Cell 21item
  17. Membrane Transporter/Ion Channel 84item
  18. Cancer Biology 26item
  19. Endocrinology and Hormones 40item
  20. Neuroscience 156item
  21. Obesity, Appetite Control & Diabetes 5item
  22. Other Signal Transduction 27item
  23. Others 167item
  24. Immunology/Inflammation 36item
  25. Cardiovascular 17item
  26. NF-κB 1 item
  27. Autophagy 1 item
  28. Metabolic Enzyme/Protease 50item
  29. Alkaloids 2item
  30. Anti-infection 11item
  31. Cell Cycle/DNA Damage 5item
  32. Acids and Aldehydes 5item
  33. Neuronal Signaling 1 item
  34. Epigenetics 1 item
  35. MAPK/ERK 1 item
Specificity
  1. Selective 315item
Reversibility
  1. Reversible 29item
  2. Irreversible 18item
Target
  1. Caspases 13item
  2. Cyclin-Dependent Kinases 13item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 5item
  5. Cathepsins 5item
  6. Histone Deacetylases (HDACs) 14item
  7. Inhibitor of apoptosis proteins (IAP) 3item
  8. Akt 5item
  9. Bcl-2 8item
  10. PI3K 5item
  11. CXCR 3item
  12. Raf 6item
  13. Aurora Kinases 8item
  14. Bcl-xl 3item
  15. CSF-1R 1 item
  16. MDM2 2item
  17. EZH2 3item
  18. mTOR 7item
  19. Bromodomains 4item
  20. AP-1 2item
  21. MMP 6item
  22. Androgen Receptors 1 item
  23. Myosin II ATPases 1 item
  24. DT-diaphorases 1 item
  25. FLT3 5item
  26. GSK-3 3item
  27. Factor Xa 1 item
  28. Farnesoid X receptors (FXRs) 1 item
  29. P-glycoprotein (P-gp) 1 item
  30. PLK 4item
  31. Chk 3item
  32. Eph Receptors 2item
  33. VEGFR 28item
  34. PDGFR 10item
  35. c-Kit 6item
  36. RET 2item
  37. Phosphodiesterases (PDEs) 2item
  38. Mcl-1 4item
  39. Thymidylate Synthase 1 item
  40. p38 2item
  41. PKB 1 item
  42. JNK 2item
  43. Bcr-Abl 5item
  44. MEK 11item
  45. DOT1L 1 item
  46. FGFR 8item
  47. Nrf2 1 item
  48. Pim 1 item
  49. Sir2-like Family Deacetylases (Sirtuins) 1 item
  50. Voltage-gated Sodium (NaV) Channels 2item
  51. Deubiquitinating enzymes (DUBs) 2item
  52. Smoothened 1 item
  53. MET 4item
  54. Src 7item
  55. RARs 1 item
  56. Trk Receptors 2item
  57. Aminopeptidases 3item
  58. STAT 2item
  59. Microtubules/Tubulins 1 item
  60. Estrogen and Related Receptors 2item
  61. EGFR 12item
  62. Hedgehog 1 item
  63. Reverse Transcriptases 2item
  64. ROCK 2item
  65. BTK 1 item
  66. RIP kinases 1 item
  67. PAK 1 item
  68. PD-1/PD-L1 interaction 1 item
  69. FAK 3item
  70. BMP and Other Activin Receptors 2item
  71. JAK 13item
  72. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  73. Syk 1 item
  74. EZH1 2item
  75. DNA-PK 2item
  76. HSP90 4item
  77. AMPK 1 item
  78. PDHK 1 item
  79. CFTR 1 item
  80. TNKS 1 item
  81. Topoisomerases 1 item
  82. Cytochrome P450 (CYP450) 5item
  83. M3 Receptors 1 item
  84. Ksp 2item
  85. Ribosomes 1 item
  86. Renin 2item
  87. HIV proteases 1 item
  88. Pepsins 1 item
  89. ErbB 2item
  90. S6 kinases 1 item
  91. Toll-like receptors (TLRs) 1 item
  92. Serine Proteases 1 item
  93. DNA Methyltransferases 2item
  94. Survivin 1 item
  95. ERK 2item
  96. c-MET 2item
  97. PKC 4item
  98. Ubiquitin-specific proteases 1 item
  99. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  100. SMYD2 1 item
  101. SGLT 2item
  102. RAD51 1 item
  103. HER2 1 item
  104. Pyk2 3item
  105. 5-HT2 Receptors 3item
  106. LRRK2 4item
  107. Voltage-gated Calcium Channels (CaV) 1 item
  108. Insulin and Insulin-like Receptors 3item
  109. PARP 5item
  110. Melanocortin (MC) Receptors 1 item
  111. Pyruvate dehydrogenases (PDH) 1 item
  112. ALK 2item
  113. Sphingosine kinases (SphKs) 1 item
  114. Dehydrogenase 1 item
  115. PKG 2item
  116. PKA 5item
  117. Myosin light chain kinases (MLCKs) 1 item
  118. D1 and D5 Receptors 2item
  119. D2 Receptors 2item
  120. D3 Receptors 1 item
  121. 5-HT1 Receptors 2item
  122. 5-HT7 Receptors 1 item
  123. AMPA 1 item
  124. NUAK1 1 item
  125. Integrin-ligand interactions 1 item
  126. NUAK2 1 item
  127. Na /H Exchangers (NHEs) 1 item
  128. MK2 2item
  129. Fatty-acid-binding proteins (FABPs) 1 item
  130. Tie-2 3item
  131. RSK 1 item
  132. Free Fatty Acid Receptors 1 item
  133. phosphatases 2item
  134. Autophagy 1 item
  135. ATM/ATR 1 item
  136. COX 10item
  137. Folate Analogue 1 item
  138. CK2 2item
  139. 20S proteasomal chymotrypsin 1 item
  140. Geranylgeranyltransferase I 1 item
  141. Farnesyltransferase 1 item
  142. Nampt 1 item
  143. eIF4F 1 item
  144. Glutaminases 1 item
  145. G9a 1 item
  146. HSV 1 item
  147. NADPH Oxidases 2item
  148. Calcium-activated chloride channels (CaCC) 1 item
  149. GPR35 1 item
  150. MAGL 1 item
  151. c-Fyn 1 item
  152. Histamine H1 Receptors 3item
  153. Na /K ATPases 1 item
  154. P110 1 item
  155. Hck 1 item
  156. SETD7 1 item
  157. GABAA Receptors 1 item
  158. iNOS 1 item
  159. Phospholipases 1 item
  160. TRP Channel 3item
  161. FoxM1 1 item
  162. Apoptosis Inducers 1 item
  163. M2 Receptors 1 item
  164. MNK 1 item
  165. CB2 Receptors 1 item
  166. Glucocorticoid Receptors 2item
  167. 15-lipoxygenases 1 item
  168. Penicillin-binding proteins (PBPs) 1 item
  169. eEF-2 1 item
  170. Inward Rectifier Potassium (Kir) Channels 2item
  171. Cdc7 1 item
  172. CMV 1 item
  173. ZAP-70 1 item
  174. Flk-1 1 item
  175. Antioxidants 1 item
  176. Cytidine deaminases 1 item
  177. angiogenesis 1 item
  178. Glucagon Receptors 1 item
  179. DPP-4 3item
  180. c-RET 2item
  181. p70 rsk 1 item
  182. FPTase 2item
  183. Microtubule/Tubulin 2item
  184. interleukin receptor 1 item
  185. Menin-MLL 2item
  186. Bfl-1 1 item
  187. sodium channels 1 item
  188. p53-MDM2 interaction 1 item
  189. KDR 2item
  190. Fyn kinase 1 item
  191. PARs 1 item
  192. p53 5item
  193. HDAC 1 item
  194. KDM 1 item
  195. c-Fms tyrosine kinase 1 item
  196. PAR 1 item
  197. cysteine protease 1 item
  198. STK 1 item
  199. HDM2 ubiquitin ligase 1 item
  200. USP1/USF1 complex 1 item
  201. IKK 1 item
  202. gp120-CD4 interaction 1 item
  203. HCV polymerase 3item
  204. Lyn kinase 1 item
  205. Ftase 1 item
  206. PC-PLC 1 item
  207. GK 1 item
  208. Antibiotic 1 item
  209. cannabinoid receptor 1 item
  210. DNA Alkylating 1 item
  211. Rev-Erb Receptors 1 item
  212. ErbB-2 1 item
  213. HIV 1 item
  214. sterol demethylase 1 item
  215. PDK-1 1 item
  216. GAPDH 1 item
  217. Histone Acetyltransferases (HATs) 2item
  218. Telomerases 1 item
  219. Prk 1 item
  220. Tyrosinases 1 item
  221. HSP70 1 item
  222. Aryl hydrocarbon receptors (AHRs) 1 item
  223. DCLK2 1 item
  224. phosphatidylinositol kinase 1 item
  225. Lck 1 item
  226. Adenosine Deaminases 1 item
  227. Thrombin Receptor 1 item
  228. DprE 1 item
  229. Flk1 2item
  230. p21 1 item
  231. Prostaglandin synthesis 1 item
  232. glutamate release 1 item
  233. PAFR 1 item
  234. Aromatases 1 item
  235. DHFR 1 item
  236. GARFT 1 item
  237. PHF 1 item
  238. UCH 1 item
  239. RHA 1 item
  240. HCV NS3-4A protease 1 item
  241. TRPC channel 1 item
  242. PKD 1 item
  243. Bcl-w 1 item
  244. NADH oxidase 1 item
  245. GLP-2 receptor 1 item
  246. SK 1 item
  247. MST 1 item
  248. PPK 1 item
  249. c-Syk 1 item
  250. CDK1/CyclinB 1 item
  251. Tph 1 item
  252. reverse transcriptase 1 item
  253. Vascular Disrupting Agents (VDA) 1 item
  254. Substance P/NK1 Receptor 1 item
  255. gp120/CD4 1 item
  256. Bax 1 item
  257. Somatostatin Receptors 1 item
  258. MTH1 1 item
  259. PTEN 1 item
  260. NS3/4a Proteases 1 item
  261. p90 S6K 1 item
Reported Experiments
  1. Animal Experiments 393item
  2. Cell Experiments 316item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acute Disseminated Candidiasis 1 item
  3. Acute Myeloid Leukemia 9item
  4. Acute Renal Failure 1 item
  5. Adrenocortical Carcinoma 2item
  6. Advanced Renal Cell Carcinoma 1 item
  7. Anesthesia 1 item
  8. Autoimmune Diseases 1 item
  9. Biliary Cancer 1 item
  10. Bladder Cancer 3item
  11. Bladder Carcinoma 2item
  12. Bladder Diseases 1 item
  13. B-lymphoid Malignancies 1 item
  14. Breast Cancer 64item
  15. Cancer 212item
  16. Candida Peritonitis 1 item
  17. Candidemia 1 item
  18. Castration-resistant Prostate Cancer 1 item
  19. Cervical Cancer 6item
  20. Cholangiocarcinoma 1 item
  21. Chronic Lymphocytic Leukemia 3item
  22. Chronic Myeloproliferative Disorders 1 item
  23. Clear Cell Renal Cell Carcinoma 1 item
  24. Colon Cancer 19item
  25. Colon Carcinoma 4item
  26. Colorectal Cancer 21item
  27. Diabetes 4item
  28. Diffuse Large B-cell Lymphoma 1 item
  29. Epilepsy 1 item
  30. Fungal Infection 2item
  31. Fungi 1 item
  32. Glioblastoma 15item
  33. Glioma 7item
  34. HCV 3item
  35. Hepatitis C 2item
  36. Hepatocellular Carcinoma 4item
  37. HIV 7item
  38. HIV Infections 3item
  39. Immunological Diseases 1 item
  40. Immunosuppressive Therapy 1 item
  41. Inflammatory Bowel Disease 1 item
  42. Inflammatory Diseases 9item
  43. Leukemia 9item
  44. Liver Cancer 4item
  45. Lung Cancer 19item
  46. Lung Carcinoma 1 item
  47. Lymphoma 11item
  48. Mantle Cell Lymphoma 1 item
  49. Melanoma 17item
  50. Mixed Lineage Leukemia 1 item
  51. Multiple Myeloma 12item
  52. Myelofibrosis 2item
  53. Myeloma 2item
  54. Neuroblastoma 2item
  55. Non-small Cell Lung Cancer 13item
  56. Ovarian Cancer 10item
  57. Pain Relief 1 item
  58. Pancreatic Cancer 22item
  59. Pancreatic Carcinoma 2item
  60. Pentacyclic Triterpenoid 1 item
  61. Prostate Cancer 27item
  62. Psoriasis 2item
  63. Pulmonary Fibrosis 2item
  64. Renal Cancer 2item
  65. Renal Cell Carcinoma 4item
  66. Rheumatoid Arthritis 8item
  67. Sarcoma 1 item
  68. Schizophrenia 3item
  69. Soft Tissue Sarcoma 1 item
  70. Squamous Cell Carcinoma 1 item
  71. Testicular Cancer 1 item
  72. Thyroid Cancer 3item
  73. Tuberculosis 1 item
  74. Type 2 Diabetes 8item