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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 211-220 of 393

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  1. MEK162 (ARRY-162, ARRY-438162)
    A1947 MEK162 (ARRY-162, ARRY-438162)
    Target: MEK
    Summary: MEK1/2 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; insoluble in DMSO
  2. Costunolide
    A3327 Costunolide
    Target: FPTase|Telomerases
    Summary: Apoptosis inducer
      ≥35.71 mg/mL
  3. MK-4827
    A3617 MK-4827
    Target: PARP
    Summary: PARP-1/-2 inhibitor,potent and selective
      ≥32 mg/mL
  4. Gemcitabine
    A8437 Gemcitabine
     1 Citation
    Summary: inhibitor of DNA synthesis
      ≥11.75 mg/mL
  5. (S)-Crizotinib
    A8802 (S)-Crizotinib
     4 Citation
    Target: MTH1
    Summary: Potent MTH1 inhibitor
      ≥33.33 mg/mL
  6. Rofecoxib
    B1454 Rofecoxib
    Target: COX
    Summary: COX-2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15.72 mg/mL
  7. MGCD-265
    A5057 MGCD-265
    Target: VEGFR|c-MET
    Summary: Met/Flt/Flk/Ron/Tie-2 inhibitor
      ≥25.9 mg/mL
  8. AZD8330
    A8374 AZD8330
    Target: MEK
    Summary: MEK 1/2 inhibitor
      ≥23.05 mg/mL
  9. Cladribine
    A2187 Cladribine
    Target: Adenosine Deaminases
    Summary: Apoptosis inducer in CLL cells
      ≥41.67 mg/mL
  10. AZD-5438
    A8326 AZD-5438
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK1/2/9 inhibitor
      insoluble in H2O; ≥18.55 mg/mL

Items 211-220 of 393

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Category
  1. Proteases 33item
  2. Apoptosis 56item
  3. Chromatin/Epigenetics 47item
  4. Metabolism 24item
  5. MAPK Signaling 18item
  6. Tyrosine Kinase 65item
  7. DNA Damage/DNA Repair 28item
  8. PI3K/Akt/mTOR Signaling 21item
  9. Microbiology & Virology 17item
  10. Cell Cycle/Checkpoint 29item
  11. Ubiquitination/ Proteasome 7item
  12. JAK/STAT Signaling 21item
  13. TGF-β / Smad Signaling 10item
  14. Angiogenesis 4item
  15. GPCR/G protein 16item
  16. Stem Cell 10item
  17. Membrane Transporter/Ion Channel 16item
  18. Endocrinology and Hormones 6item
  19. Neuroscience 23item
  20. Obesity, Appetite Control & Diabetes 2item
  21. Other Signal Transduction 4item
  22. Others 22item
  23. Immunology/Inflammation 11item
  24. Cardiovascular 2item
  25. NF-κB 1 item
Specificity
  1. Selective 265item
Reversibility
  1. Reversible 25item
  2. Irreversible 15item
Target
  1. Caspases 8item
  2. Cyclin-Dependent Kinases 11item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 3item
  5. Cathepsins 3item
  6. Histone Deacetylases (HDACs) 12item
  7. Inhibitor of apoptosis proteins (IAP) 3item
  8. Akt 5item
  9. Bcl-2 8item
  10. PI3K 5item
  11. CXCR 3item
  12. Raf 6item
  13. Aurora Kinases 6item
  14. Bcl-xl 2item
  15. CSF-1R 1 item
  16. MDM2 2item
  17. EZH2 2item
  18. mTOR 7item
  19. Bromodomains 4item
  20. AP-1 2item
  21. MMP 4item
  22. Androgen Receptors 1 item
  23. Myosin II ATPases 1 item
  24. DT-diaphorases 1 item
  25. FLT3 5item
  26. GSK-3 2item
  27. Factor Xa 1 item
  28. Farnesoid X receptors (FXRs) 1 item
  29. P-glycoprotein (P-gp) 1 item
  30. PLK 4item
  31. Chk 2item
  32. Eph Receptors 2item
  33. VEGFR 28item
  34. PDGFR 10item
  35. c-Kit 6item
  36. RET 2item
  37. Phosphodiesterases (PDEs) 2item
  38. Mcl-1 3item
  39. Thymidylate Synthase 1 item
  40. p38 2item
  41. PKB 1 item
  42. JNK 1 item
  43. Bcr-Abl 3item
  44. MEK 8item
  45. DOT1L 1 item
  46. FGFR 8item
  47. Nrf2 1 item
  48. Pim 1 item
  49. Sir2-like Family Deacetylases (Sirtuins) 1 item
  50. Voltage-gated Sodium (NaV) Channels 2item
  51. Deubiquitinating enzymes (DUBs) 1 item
  52. Smoothened 1 item
  53. MET 4item
  54. Src 4item
  55. RARs 1 item
  56. Trk Receptors 2item
  57. Aminopeptidases 3item
  58. STAT 2item
  59. Microtubules/Tubulins 1 item
  60. Estrogen and Related Receptors 2item
  61. EGFR 11item
  62. Hedgehog 1 item
  63. Reverse Transcriptases 1 item
  64. ROCK 1 item
  65. BTK 1 item
  66. RIP kinases 1 item
  67. PAK 1 item
  68. FAK 3item
  69. BMP and Other Activin Receptors 2item
  70. JAK 11item
  71. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  72. Syk 1 item
  73. EZH1 2item
  74. DNA-PK 2item
  75. HSP90 4item
  76. AMPK 1 item
  77. PDHK 1 item
  78. CFTR 1 item
  79. TNKS 1 item
  80. Topoisomerases 1 item
  81. Cytochrome P450 (CYP450) 5item
  82. M3 Receptors 1 item
  83. Ksp 2item
  84. Renin 1 item
  85. ErbB 2item
  86. S6 kinases 1 item
  87. Toll-like receptors (TLRs) 1 item
  88. Serine Proteases 1 item
  89. DNA Methyltransferases 2item
  90. Survivin 1 item
  91. ERK 2item
  92. c-MET 2item
  93. PKC 3item
  94. Ubiquitin-specific proteases 1 item
  95. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  96. SGLT 2item
  97. RAD51 1 item
  98. HER2 1 item
  99. Pyk2 3item
  100. 5-HT2 Receptors 3item
  101. LRRK2 4item
  102. Voltage-gated Calcium Channels (CaV) 1 item
  103. Insulin and Insulin-like Receptors 3item
  104. PARP 4item
  105. Melanocortin (MC) Receptors 1 item
  106. Pyruvate dehydrogenases (PDH) 1 item
  107. ALK 2item
  108. Sphingosine kinases (SphKs) 1 item
  109. Dehydrogenase 1 item
  110. PKG 1 item
  111. PKA 4item
  112. D1 and D5 Receptors 2item
  113. D2 Receptors 2item
  114. D3 Receptors 1 item
  115. 5-HT1 Receptors 2item
  116. 5-HT7 Receptors 1 item
  117. AMPA 1 item
  118. MK2 2item
  119. Fatty-acid-binding proteins (FABPs) 1 item
  120. Tie-2 3item
  121. RSK 1 item
  122. Free Fatty Acid Receptors 1 item
  123. phosphatases 2item
  124. Autophagy 1 item
  125. ATM/ATR 1 item
  126. COX 9item
  127. Folate Analogue 1 item
  128. CK2 1 item
  129. 20S proteasomal chymotrypsin 1 item
  130. Geranylgeranyltransferase I 1 item
  131. Farnesyltransferase 1 item
  132. Nampt 1 item
  133. eIF4F 1 item
  134. Glutaminases 1 item
  135. HSV 1 item
  136. NADPH Oxidases 2item
  137. Calcium-activated chloride channels (CaCC) 1 item
  138. GPR35 1 item
  139. MAGL 1 item
  140. Histamine H1 Receptors 3item
  141. Na /K ATPases 1 item
  142. P110 1 item
  143. Hck 1 item
  144. GABAA Receptors 1 item
  145. Phospholipases 1 item
  146. TRP Channel 3item
  147. FoxM1 1 item
  148. M2 Receptors 1 item
  149. MNK 1 item
  150. Glucocorticoid Receptors 2item
  151. 15-lipoxygenases 1 item
  152. eEF-2 1 item
  153. Inward Rectifier Potassium (Kir) Channels 1 item
  154. Cdc7 1 item
  155. CMV 1 item
  156. ZAP-70 1 item
  157. Flk-1 1 item
  158. Antioxidants 1 item
  159. Cytidine deaminases 1 item
  160. angiogenesis 1 item
  161. Glucagon Receptors 1 item
  162. DPP-4 3item
  163. c-RET 2item
  164. p70 rsk 1 item
  165. FPTase 2item
  166. Microtubule/Tubulin 2item
  167. interleukin receptor 1 item
  168. Bfl-1 1 item
  169. p53-MDM2 interaction 1 item
  170. KDR 2item
  171. Fyn kinase 1 item
  172. PARs 1 item
  173. p53 5item
  174. HDAC 1 item
  175. c-Fms tyrosine kinase 1 item
  176. PAR 1 item
  177. cysteine protease 1 item
  178. HDM2 ubiquitin ligase 1 item
  179. IKK 1 item
  180. gp120-CD4 interaction 1 item
  181. HCV polymerase 2item
  182. Lyn kinase 1 item
  183. Ftase 1 item
  184. PC-PLC 1 item
  185. GK 1 item
  186. Antibiotic 1 item
  187. cannabinoid receptor 1 item
  188. DNA Alkylating 1 item
  189. Rev-Erb Receptors 1 item
  190. ErbB-2 1 item
  191. HIV 1 item
  192. sterol demethylase 1 item
  193. PDK-1 1 item
  194. GAPDH 1 item
  195. Histone Acetyltransferases (HATs) 1 item
  196. Telomerases 1 item
  197. Prk 1 item
  198. Tyrosinases 1 item
  199. HSP70 1 item
  200. Aryl hydrocarbon receptors (AHRs) 1 item
  201. DCLK2 1 item
  202. phosphatidylinositol kinase 1 item
  203. Adenosine Deaminases 1 item
  204. Thrombin Receptor 1 item
  205. DprE 1 item
  206. Flk1 2item
  207. p21 1 item
  208. Prostaglandin synthesis 1 item
  209. glutamate release 1 item
  210. PAFR 1 item
  211. Aromatases 1 item
  212. DHFR 1 item
  213. GARFT 1 item
  214. UCH 1 item
  215. RHA 1 item
  216. HCV NS3-4A protease 1 item
  217. TRPC channel 1 item
  218. PKD 1 item
  219. Bcl-w 1 item
  220. SK 1 item
  221. MST 1 item
  222. PPK 1 item
  223. c-Syk 1 item
  224. CDK1/CyclinB 1 item
  225. Tph 1 item
  226. reverse transcriptase 1 item
  227. Vascular Disrupting Agents (VDA) 1 item
  228. Substance P/NK1 Receptor 1 item
  229. gp120/CD4 1 item
  230. Bax 1 item
  231. Somatostatin Receptors 1 item
  232. MTH1 1 item
  233. PTEN 1 item
  234. NS3/4a Proteases 1 item
  235. p90 S6K 1 item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acute Disseminated Candidiasis 1 item
  3. Acute Myeloid Leukemia 9item
  4. Acute Renal Failure 1 item
  5. Adrenocortical Carcinoma 2item
  6. Advanced Renal Cell Carcinoma 1 item
  7. Anesthesia 1 item
  8. Autoimmune Diseases 1 item
  9. Biliary Cancer 1 item
  10. Bladder Cancer 3item
  11. Bladder Carcinoma 2item
  12. Bladder Diseases 1 item
  13. B-lymphoid Malignancies 1 item
  14. Breast Cancer 63item
  15. Cancer 197item
  16. Candida Peritonitis 1 item
  17. Candidemia 1 item
  18. Castration-resistant Prostate Cancer 1 item
  19. Cervical Cancer 6item
  20. Cholangiocarcinoma 1 item
  21. Chronic Lymphocytic Leukemia 3item
  22. Chronic Myeloproliferative Disorders 1 item
  23. Clear Cell Renal Cell Carcinoma 1 item
  24. Colon Cancer 16item
  25. Colon Carcinoma 4item
  26. Colorectal Cancer 20item
  27. Diabetes 3item
  28. Diffuse Large B-cell Lymphoma 1 item
  29. Epilepsy 1 item
  30. Fungal Infection 2item
  31. Fungi 1 item
  32. Glioblastoma 15item
  33. Glioma 6item
  34. HCV 2item
  35. Hepatitis C 2item
  36. Hepatocellular Carcinoma 4item
  37. HIV 6item
  38. HIV Infections 3item
  39. Immunological Diseases 1 item
  40. Immunosuppressive Therapy 1 item
  41. Inflammatory Bowel Disease 1 item
  42. Inflammatory Diseases 9item
  43. Leukemia 8item
  44. Liver Cancer 4item
  45. Lung Cancer 18item
  46. Lung Carcinoma 1 item
  47. Lymphoma 9item
  48. Mantle Cell Lymphoma 1 item
  49. Melanoma 15item
  50. Mixed Lineage Leukemia 1 item
  51. Multiple Myeloma 11item
  52. Myelofibrosis 2item
  53. Myeloma 2item
  54. Neuroblastoma 2item
  55. Non-small Cell Lung Cancer 13item
  56. Ovarian Cancer 10item
  57. Pain Relief 1 item
  58. Pancreatic Cancer 21item
  59. Pancreatic Carcinoma 2item
  60. Pentacyclic Triterpenoid 1 item
  61. Prostate Cancer 26item
  62. Psoriasis 2item
  63. Pulmonary Fibrosis 2item
  64. Renal Cancer 2item
  65. Renal Cell Carcinoma 4item
  66. Rheumatoid Arthritis 7item
  67. Sarcoma 1 item
  68. Schizophrenia 3item
  69. Soft Tissue Sarcoma 1 item
  70. Squamous Cell Carcinoma 1 item
  71. Testicular Cancer 1 item
  72. Thyroid Cancer 3item
  73. Tuberculosis 1 item
  74. Type 2 Diabetes 7item