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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 271-280 of 315

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  1. Tosedostat (CHR2797)
    A4355 Tosedostat (CHR2797)
     1 Citation
    Target: Aminopeptidases
    Summary: Aminopeptidase inhibitor
      ≥40.6 mg/mL
  2. Sitagliptin phosphate monohydrate
    A4036 Sitagliptin phosphate monohydrate
     5 Citation
    Target: DPP-4
    Summary: Potent DPP-4 inhibitor
      ≥23.8 mg/mL
  3. CVT-313
    A3336 CVT-313
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Cdk2 inhibitor
      ≥20 mg/mL
  4. MK 0893
    A3608 MK 0893
    Target: Insulin and Insulin-like Receptors|Glucagon Receptors
    Summary: Glucagon receptor/IGF-1R antagonist
      ≥24.05 mg/mL
  5. Saquinavir mesylate
    A3791 Saquinavir mesylate
    Summary: HIV Protease Inhibitor
  6. GDC-0449 (Vismodegib)
    A3021 GDC-0449 (Vismodegib)
     1 Citation
    Target: P-glycoprotein (P-gp)|Hedgehog
    Summary: Hedgehog antagonist,potent and selective
      ≥21.08 mg/mL
  7. TUG-770
    A3895 TUG-770
    Target: Free Fatty Acid Receptors
    Summary: FFA1/GPR40 agonist
      insoluble in H2O; ≥11.85 mg/mL
  8. Trametinib (GSK1120212)
    A3018 Trametinib (GSK1120212)
     7 Citation
    Target: MEK
    Summary: MEK1 and MEK2 inhibitor, potent and selective
      insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL
  9. AC 55541
    A8669 AC 55541
    Target: PAR
    Summary: PAR2 agonist,potent and selective
      Soluble in DMSO
  10. GNE0877
    B4633 GNE0877
    Target: LRRK2
    Summary: Potent and selective LRRK2 inhibitor
      ≥21 mg/mL

Items 271-280 of 315

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Category
  1. Proteases 34item
  2. Apoptosis 43item
  3. Chromatin/Epigenetics 43item
  4. Metabolism 16item
  5. MAPK Signaling 18item
  6. Tyrosine Kinase 52item
  7. DNA Damage/DNA Repair 16item
  8. PI3K/Akt/mTOR Signaling 17item
  9. Microbiology & Virology 11item
  10. Cell Cycle/Checkpoint 24item
  11. Ubiquitination/ Proteasome 6item
  12. JAK/STAT Signaling 16item
  13. TGF-β / Smad Signaling 10item
  14. Angiogenesis 4item
  15. GPCR/G protein 14item
  16. Stem Cell 8item
  17. Membrane Transporter/Ion Channel 12item
  18. Endocrinology and Hormones 5item
  19. Neuroscience 15item
  20. Obesity, Appetite Control & Diabetes 2item
  21. Other Signal Transduction 2item
  22. Others 18item
  23. Immunology/Inflammation 9item
  24. Cardiovascular 1 item
Reversibility
  1. Reversible 22item
  2. Irreversible 12item
Target
  1. Caspases 10item
  2. Cyclin-Dependent Kinases 10item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 3item
  5. Cathepsins 5item
  6. Histone Deacetylases (HDACs) 11item
  7. Inhibitor of apoptosis proteins (IAP) 3item
  8. Akt 2item
  9. Bcl-2 5item
  10. PI3K 4item
  11. CXCR 3item
  12. Raf 4item
  13. Aurora Kinases 6item
  14. Bcl-xl 3item
  15. CSF-1R 1 item
  16. MDM2 2item
  17. EZH2 3item
  18. mTOR 6item
  19. Bromodomains 2item
  20. AP-1 2item
  21. MMP 6item
  22. Androgen Receptors 1 item
  23. Myosin II ATPases 1 item
  24. DT-diaphorases 1 item
  25. FLT3 4item
  26. GSK-3 1 item
  27. Factor Xa 1 item
  28. Farnesoid X receptors (FXRs) 1 item
  29. P-glycoprotein (P-gp) 1 item
  30. PLK 1 item
  31. Chk 3item
  32. Eph Receptors 2item
  33. VEGFR 19item
  34. PDGFR 8item
  35. c-Kit 4item
  36. RET 2item
  37. Phosphodiesterases (PDEs) 1 item
  38. Mcl-1 3item
  39. p38 2item
  40. PKB 1 item
  41. JNK 2item
  42. Bcr-Abl 4item
  43. MEK 10item
  44. DOT1L 1 item
  45. FGFR 4item
  46. Pim 1 item
  47. Voltage-gated Sodium (NaV) Channels 1 item
  48. Deubiquitinating enzymes (DUBs) 1 item
  49. Smoothened 1 item
  50. MET 4item
  51. Src 6item
  52. RARs 1 item
  53. Trk Receptors 2item
  54. Aminopeptidases 2item
  55. STAT 1 item
  56. Microtubules/Tubulins 1 item
  57. Estrogen and Related Receptors 1 item
  58. EGFR 8item
  59. Hedgehog 1 item
  60. Reverse Transcriptases 1 item
  61. ROCK 2item
  62. BTK 1 item
  63. RIP kinases 1 item
  64. PAK 1 item
  65. FAK 3item
  66. BMP and Other Activin Receptors 2item
  67. JAK 8item
  68. Syk 1 item
  69. EZH1 2item
  70. DNA-PK 2item
  71. HSP90 4item
  72. AMPK 1 item
  73. PDHK 1 item
  74. CFTR 1 item
  75. TNKS 1 item
  76. Cytochrome P450 (CYP450) 3item
  77. M3 Receptors 1 item
  78. Ksp 1 item
  79. Ribosomes 1 item
  80. Renin 2item
  81. HIV proteases 1 item
  82. Pepsins 1 item
  83. ErbB 2item
  84. S6 kinases 1 item
  85. DNA Methyltransferases 2item
  86. Survivin 1 item
  87. ERK 1 item
  88. c-MET 2item
  89. PKC 1 item
  90. Ubiquitin-specific proteases 1 item
  91. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  92. SMYD2 1 item
  93. SGLT 2item
  94. RAD51 1 item
  95. HER2 1 item
  96. Pyk2 3item
  97. 5-HT2 Receptors 3item
  98. LRRK2 3item
  99. Insulin and Insulin-like Receptors 2item
  100. PARP 1 item
  101. Melanocortin (MC) Receptors 1 item
  102. Sphingosine kinases (SphKs) 1 item
  103. Dehydrogenase 1 item
  104. PKG 1 item
  105. PKA 1 item
  106. Myosin light chain kinases (MLCKs) 1 item
  107. D1 and D5 Receptors 1 item
  108. D2 Receptors 1 item
  109. D3 Receptors 1 item
  110. 5-HT1 Receptors 1 item
  111. 5-HT7 Receptors 1 item
  112. AMPA 1 item
  113. NUAK1 1 item
  114. Integrin-ligand interactions 1 item
  115. NUAK2 1 item
  116. Na /H Exchangers (NHEs) 1 item
  117. MK2 2item
  118. Fatty-acid-binding proteins (FABPs) 1 item
  119. Tie-2 2item
  120. Free Fatty Acid Receptors 1 item
  121. phosphatases 2item
  122. ATM/ATR 1 item
  123. COX 7item
  124. Folate Analogue 1 item
  125. CK2 2item
  126. 20S proteasomal chymotrypsin 1 item
  127. Geranylgeranyltransferase I 1 item
  128. Farnesyltransferase 1 item
  129. eIF4F 1 item
  130. G9a 1 item
  131. NADPH Oxidases 2item
  132. Calcium-activated chloride channels (CaCC) 1 item
  133. GPR35 1 item
  134. MAGL 1 item
  135. c-Fyn 1 item
  136. Na /K ATPases 1 item
  137. P110 1 item
  138. Hck 1 item
  139. SETD7 1 item
  140. iNOS 1 item
  141. Phospholipases 1 item
  142. TRP Channel 3item
  143. FoxM1 1 item
  144. Apoptosis Inducers 1 item
  145. M2 Receptors 1 item
  146. CB2 Receptors 1 item
  147. Glucocorticoid Receptors 1 item
  148. 15-lipoxygenases 1 item
  149. eEF-2 1 item
  150. Inward Rectifier Potassium (Kir) Channels 2item
  151. Cdc7 1 item
  152. CMV 1 item
  153. ZAP-70 1 item
  154. Flk-1 1 item
  155. Cytidine deaminases 1 item
  156. angiogenesis 1 item
  157. Glucagon Receptors 1 item
  158. DPP-4 2item
  159. c-RET 1 item
  160. FPTase 1 item
  161. p53-MDM2 interaction 1 item
  162. PARs 1 item
  163. c-Fms tyrosine kinase 1 item
  164. PAR 1 item
  165. STK 1 item
  166. IKK 1 item
  167. HCV polymerase 2item
  168. Lyn kinase 1 item
  169. Ftase 1 item
  170. PC-PLC 1 item
  171. cannabinoid receptor 1 item
  172. Rev-Erb Receptors 1 item
  173. Histone Acetyltransferases (HATs) 1 item
  174. DCLK2 1 item
  175. Lck 1 item
  176. PKD 1 item
  177. Bcl-w 1 item
  178. SK 1 item
  179. MST 1 item
  180. Substance P/NK1 Receptor 1 item
  181. gp120/CD4 1 item
  182. MTH1 1 item
Reported Experiments
  1. Animal Experiments 265item
  2. Cell Experiments 178item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acute Disseminated Candidiasis 1 item
  3. Acute Myeloid Leukemia 9item
  4. Acute Renal Failure 1 item
  5. Adrenocortical Carcinoma 2item
  6. Advanced Renal Cell Carcinoma 1 item
  7. Autoimmune Diseases 1 item
  8. Biliary Cancer 1 item
  9. Bladder Cancer 3item
  10. Bladder Carcinoma 2item
  11. Bladder Diseases 1 item
  12. B-lymphoid Malignancies 1 item
  13. Breast Cancer 59item
  14. Cancer 162item
  15. Candida Peritonitis 1 item
  16. Candidemia 1 item
  17. Castration-resistant Prostate Cancer 1 item
  18. Cervical Cancer 5item
  19. Cholangiocarcinoma 1 item
  20. Chronic Lymphocytic Leukemia 3item
  21. Chronic Myeloproliferative Disorders 1 item
  22. Clear Cell Renal Cell Carcinoma 1 item
  23. Colon Cancer 17item
  24. Colon Carcinoma 4item
  25. Colorectal Cancer 20item
  26. Diabetes 3item
  27. Diffuse Large B-cell Lymphoma 1 item
  28. Fungal Infection 2item
  29. Glioblastoma 15item
  30. Glioma 7item
  31. HCV 1 item
  32. Hepatitis C 1 item
  33. Hepatocellular Carcinoma 4item
  34. HIV 2item
  35. HIV Infections 2item
  36. Immunological Diseases 1 item
  37. Immunosuppressive Therapy 1 item
  38. Inflammatory Bowel Disease 1 item
  39. Inflammatory Diseases 8item
  40. Leukemia 7item
  41. Liver Cancer 4item
  42. Lung Cancer 19item
  43. Lung Carcinoma 1 item
  44. Lymphoma 11item
  45. Mantle Cell Lymphoma 1 item
  46. Melanoma 17item
  47. Mixed Lineage Leukemia 1 item
  48. Multiple Myeloma 11item
  49. Myelofibrosis 2item
  50. Myeloma 2item
  51. Neuroblastoma 2item
  52. Non-small Cell Lung Cancer 12item
  53. Ovarian Cancer 9item
  54. Pain Relief 1 item
  55. Pancreatic Cancer 22item
  56. Pancreatic Carcinoma 2item
  57. Prostate Cancer 26item
  58. Psoriasis 2item
  59. Pulmonary Fibrosis 2item
  60. Renal Cancer 2item
  61. Renal Cell Carcinoma 4item
  62. Rheumatoid Arthritis 8item
  63. Sarcoma 1 item
  64. Schizophrenia 2item
  65. Soft Tissue Sarcoma 1 item
  66. Squamous Cell Carcinoma 1 item
  67. Testicular Cancer 1 item
  68. Thyroid Cancer 3item
  69. Type 2 Diabetes 8item