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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 41-50 of 212

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  1. (+)-Apogossypol
    B4902 (+)-Apogossypol
    Target: Bcl-2
    Summary: inhibitor of Bcl-2 family proteins
      insoluble in H2O; ≥16.2 mg/mL
  2. Regorafenib hydrochloride
    A3750 Regorafenib hydrochloride
    Target: Raf|VEGFR|PDGFR|c-Kit|c-RET
    Summary: Tyrosine kinase inhibitor
      ≥25.95 mg/mL
  3. P005091
    A3023 P005091
     1 Citation
    Target: Ubiquitin-specific proteases
    Summary: Ubiquitin-specific protease 7 (USP7) inhibitor
      insoluble in H2O; insoluble in EtOH; ≥17.4 mg/mL
  4. Afatinib (BIBW2992)
    A8247 Afatinib (BIBW2992)
     1 Citation
    Target: EGFR
    Summary: Irreversible EGFR/HER2 inhibitor
      ≥24.3 mg/mL
  5. Entinostat (MS-275,SNDX-275)
    A8171 Entinostat (MS-275,SNDX-275)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1 and HDAC3 inhibitor
      insoluble in H2O; ≥18.8 mg/mL
  6. AC480 (BMS-599626)
    A2822 AC480 (BMS-599626)
    Target: EGFR
    Summary: HER1/2 inhibitor,selective and efficacious
      ≥28.35 mg/mL
  7. PP 1
    A8215 PP 1
    Target: Src|EGFR|JAK|ZAP-70
    Summary: Src family tyrosine kinase inhibitor
  8. Lapatinib
    A8218 Lapatinib
     2 Citation
    Target: ErbB
    Summary: EGFR/HER2 inhibitor,potent,selective and reversible
      ≥29.05 mg/mL
  9. Erteberel (LY500307)
    B1518 Erteberel (LY500307)
    Target: Estrogen and Related Receptors
    Summary: ERβ agonist, potent and selective
      insoluble in H2O; ≥14.1 mg/mL
  10. DMXAA (Vadimezan)
    A8233 DMXAA (Vadimezan)
     2 Citation
    Target: DT-diaphorases
    Summary: Tumnor vascular disrupting agent, apoptosis inducer
      insoluble in H2O; insoluble in EtOH; ≥14.1 mg/mL

Items 41-50 of 212

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Category
  1. Proteases 14item
  2. Apoptosis 39item
  3. Chromatin/Epigenetics 34item
  4. Metabolism 12item
  5. MAPK Signaling 13item
  6. Tyrosine Kinase 51item
  7. DNA Damage/DNA Repair 18item
  8. PI3K/Akt/mTOR Signaling 14item
  9. Microbiology & Virology 2item
  10. Cell Cycle/Checkpoint 25item
  11. Ubiquitination/ Proteasome 5item
  12. JAK/STAT Signaling 15item
  13. TGF-β / Smad Signaling 7item
  14. Angiogenesis 2item
  15. GPCR/G protein 2item
  16. Stem Cell 8item
  17. Endocrinology and Hormones 2item
  18. Neuroscience 3item
  19. Others 6item
  20. Immunology/Inflammation 4item
Specificity
  1. Selective 162item
Reversibility
  1. Reversible 17item
  2. Irreversible 8item
Target
  1. Caspases 4item
  2. Cyclin-Dependent Kinases 11item
  3. Proteasome 2item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 11item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 5item
  8. Bcl-2 7item
  9. PI3K 4item
  10. CXCR 1 item
  11. Raf 6item
  12. Aurora Kinases 5item
  13. Bcl-xl 2item
  14. CSF-1R 1 item
  15. MDM2 2item
  16. EZH2 2item
  17. mTOR 5item
  18. Bromodomains 2item
  19. AP-1 1 item
  20. MMP 3item
  21. Androgen Receptors 1 item
  22. DT-diaphorases 1 item
  23. FLT3 3item
  24. GSK-3 2item
  25. P-glycoprotein (P-gp) 1 item
  26. PLK 3item
  27. Chk 2item
  28. Eph Receptors 2item
  29. VEGFR 25item
  30. PDGFR 9item
  31. c-Kit 5item
  32. RET 2item
  33. Phosphodiesterases (PDEs) 1 item
  34. Mcl-1 3item
  35. Thymidylate Synthase 1 item
  36. JNK 1 item
  37. Bcr-Abl 3item
  38. MEK 7item
  39. DOT1L 1 item
  40. FGFR 5item
  41. Deubiquitinating enzymes (DUBs) 2item
  42. Smoothened 1 item
  43. MET 4item
  44. Src 3item
  45. RARs 1 item
  46. Trk Receptors 1 item
  47. Aminopeptidases 1 item
  48. STAT 2item
  49. Microtubules/Tubulins 1 item
  50. Estrogen and Related Receptors 1 item
  51. EGFR 10item
  52. Hedgehog 1 item
  53. PAK 1 item
  54. FAK 3item
  55. BMP and Other Activin Receptors 1 item
  56. JAK 7item
  57. Syk 1 item
  58. EZH1 1 item
  59. DNA-PK 1 item
  60. HSP90 4item
  61. TNKS 1 item
  62. Cytochrome P450 (CYP450) 2item
  63. Ksp 1 item
  64. ErbB 2item
  65. DNA Methyltransferases 2item
  66. Survivin 1 item
  67. ERK 2item
  68. c-MET 2item
  69. PKC 4item
  70. Ubiquitin-specific proteases 1 item
  71. SMYD2 1 item
  72. SGLT 1 item
  73. RAD51 1 item
  74. HER2 1 item
  75. Pyk2 3item
  76. Insulin and Insulin-like Receptors 1 item
  77. PARP 2item
  78. Pyruvate dehydrogenases (PDH) 1 item
  79. ALK 1 item
  80. Dehydrogenase 1 item
  81. PKG 2item
  82. PKA 5item
  83. Myosin light chain kinases (MLCKs) 1 item
  84. Integrin-ligand interactions 1 item
  85. MK2 1 item
  86. Tie-2 2item
  87. RSK 1 item
  88. Autophagy 1 item
  89. COX 3item
  90. Folate Analogue 1 item
  91. 20S proteasomal chymotrypsin 1 item
  92. Geranylgeranyltransferase I 1 item
  93. Farnesyltransferase 1 item
  94. Nampt 1 item
  95. eIF4F 1 item
  96. Glutaminases 1 item
  97. MAGL 1 item
  98. P110 1 item
  99. Hck 1 item
  100. iNOS 1 item
  101. FoxM1 1 item
  102. Apoptosis Inducers 1 item
  103. MNK 1 item
  104. eEF-2 1 item
  105. Cdc7 1 item
  106. CMV 1 item
  107. ZAP-70 1 item
  108. Flk-1 1 item
  109. Cytidine deaminases 1 item
  110. angiogenesis 1 item
  111. c-RET 1 item
  112. p70 rsk 1 item
  113. Microtubule/Tubulin 1 item
  114. Bfl-1 1 item
  115. p53-MDM2 interaction 1 item
  116. KDR 2item
  117. p53 3item
  118. HDAC 1 item
  119. HDM2 ubiquitin ligase 1 item
  120. DNA Alkylating 1 item
  121. ErbB-2 1 item
  122. PDK-1 1 item
  123. Prk 1 item
  124. HSP70 1 item
  125. Flk1 2item
  126. DHFR 1 item
  127. GARFT 1 item
  128. RHA 1 item
  129. Bcl-w 1 item
  130. SK 1 item
  131. PPK 1 item
  132. c-Syk 1 item
  133. CDK1/CyclinB 1 item
  134. Substance P/NK1 Receptor 1 item
  135. Bax 1 item
Reported Experiments
  1. Animal Experiments 197item
  2. Cell Experiments 128item