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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 61-70 of 316

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  1. AC480 (BMS-599626)
    A2822 AC480 (BMS-599626)
    Target: EGFR
    Summary: HER1/2 inhibitor,selective and efficacious
      ≥28.35 mg/mL
  2. PP 1
    A8215 PP 1
    Target: Src|EGFR|JAK|ZAP-70
    Summary: Src family tyrosine kinase inhibitor
  3. GW441756
    B2297 GW441756
     1 Citation
    Target: Trk Receptors
    Summary: TrkA inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥13.75 mg/mL
  4. Lapatinib
    A8218 Lapatinib
     2 Citation
    Target: ErbB
    Summary: EGFR/HER2 inhibitor,potent,selective and reversible
      ≥29.05 mg/mL
  5. DMXAA (Vadimezan)
    A8233 DMXAA (Vadimezan)
     2 Citation
    Target: DT-diaphorases
    Summary: Tumnor vascular disrupting agent, apoptosis inducer
      insoluble in H2O; insoluble in EtOH; ≥14.1 mg/mL
  6. GSK1838705A
    A8440 GSK1838705A
    Target: Insulin and Insulin-like Receptors|ALK
    Summary: IGF-IR/IR/ALK inhibitor, ATP-competitive
      ≥26.65 mg/mL
  7. GSK1059615
    B2176 GSK1059615
    Target: PI3K|mTOR
    Summary: PI3K and mTOR inhibitor,potent and reversible
      insoluble in EtOH; insoluble in H2O; ≥8.33 mg/mL
  8. AMG-517
    A1174 AMG-517
    Target: TRP Channel
    Summary: TRPV1 antagonist,potent and highly selective
      ≥21.5 mg/mL
  9. MG-262
    A8179 MG-262
     1 Citation
    Target: Proteasome
    Summary: Proteasome inhibitor
      ≥24.57 mg/mL
  10. AT7519
    A5719 AT7519
    Target: Cyclin-Dependent Kinases
    Summary: Multi-CDK inhibitor

Items 61-70 of 316

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Category
  1. Proteases 25item
  2. Apoptosis 46item
  3. Chromatin/Epigenetics 39item
  4. Metabolism 18item
  5. MAPK Signaling 10item
  6. Tyrosine Kinase 46item
  7. DNA Damage/DNA Repair 18item
  8. PI3K/Akt/mTOR Signaling 16item
  9. Microbiology & Virology 18item
  10. Cell Cycle/Checkpoint 23item
  11. Ubiquitination/ Proteasome 8item
  12. JAK/STAT Signaling 17item
  13. TGF-β / Smad Signaling 6item
  14. Angiogenesis 3item
  15. GPCR/G protein 11item
  16. Stem Cell 8item
  17. Membrane Transporter/Ion Channel 13item
  18. Cancer Biology 2item
  19. Endocrinology and Hormones 4item
  20. Neuroscience 20item
  21. Obesity, Appetite Control & Diabetes 1 item
  22. Other Signal Transduction 5item
  23. Others 24item
  24. Immunology/Inflammation 10item
  25. Cardiovascular 2item
  26. NF-κB 1 item
Specificity
  1. Selective 178item
Reversibility
  1. Reversible 18item
  2. Irreversible 12item
Target
  1. Caspases 7item
  2. Cyclin-Dependent Kinases 9item
  3. Proteasome 4item
  4. Cathepsins 2item
  5. Histone Deacetylases (HDACs) 6item
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 4item
  8. Bcl-2 8item
  9. PI3K 3item
  10. CXCR 2item
  11. Raf 4item
  12. Aurora Kinases 7item
  13. Bcl-xl 3item
  14. CSF-1R 1 item
  15. MDM2 1 item
  16. EZH2 1 item
  17. mTOR 4item
  18. Bromodomains 3item
  19. AP-1 2item
  20. MMP 3item
  21. Myosin II ATPases 1 item
  22. DT-diaphorases 1 item
  23. FLT3 5item
  24. GSK-3 2item
  25. Factor Xa 1 item
  26. Farnesoid X receptors (FXRs) 1 item
  27. PLK 4item
  28. Chk 1 item
  29. Eph Receptors 2item
  30. VEGFR 20item
  31. PDGFR 8item
  32. c-Kit 5item
  33. RET 1 item
  34. Phosphodiesterases (PDEs) 2item
  35. Mcl-1 4item
  36. Thymidylate Synthase 1 item
  37. p38 1 item
  38. PKB 1 item
  39. Bcr-Abl 3item
  40. MEK 7item
  41. DOT1L 1 item
  42. FGFR 6item
  43. Nrf2 1 item
  44. Pim 1 item
  45. Sir2-like Family Deacetylases (Sirtuins) 1 item
  46. Voltage-gated Sodium (NaV) Channels 2item
  47. MET 3item
  48. Src 4item
  49. RARs 1 item
  50. Trk Receptors 2item
  51. Aminopeptidases 1 item
  52. STAT 2item
  53. Estrogen and Related Receptors 1 item
  54. EGFR 7item
  55. Reverse Transcriptases 1 item
  56. ROCK 1 item
  57. FAK 2item
  58. JAK 10item
  59. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  60. EZH1 1 item
  61. DNA-PK 2item
  62. HSP90 2item
  63. AMPK 1 item
  64. Topoisomerases 1 item
  65. Cytochrome P450 (CYP450) 4item
  66. Ksp 1 item
  67. Renin 1 item
  68. ErbB 1 item
  69. Toll-like receptors (TLRs) 1 item
  70. DNA Methyltransferases 1 item
  71. ERK 1 item
  72. c-MET 2item
  73. PKC 3item
  74. Pyk2 2item
  75. 5-HT2 Receptors 1 item
  76. LRRK2 4item
  77. Voltage-gated Calcium Channels (CaV) 1 item
  78. Insulin and Insulin-like Receptors 3item
  79. PARP 4item
  80. Pyruvate dehydrogenases (PDH) 1 item
  81. ALK 2item
  82. Sphingosine kinases (SphKs) 1 item
  83. PKG 1 item
  84. PKA 4item
  85. 5-HT1 Receptors 1 item
  86. MK2 1 item
  87. Tie-2 3item
  88. RSK 1 item
  89. phosphatases 1 item
  90. Autophagy 1 item
  91. ATM/ATR 1 item
  92. COX 9item
  93. CK2 2item
  94. 20S proteasomal chymotrypsin 1 item
  95. Geranylgeranyltransferase I 1 item
  96. Farnesyltransferase 1 item
  97. Nampt 1 item
  98. eIF4F 1 item
  99. Glutaminases 1 item
  100. HSV 1 item
  101. NADPH Oxidases 2item
  102. Calcium-activated chloride channels (CaCC) 1 item
  103. GPR35 1 item
  104. MAGL 1 item
  105. Histamine H1 Receptors 3item
  106. Na /K ATPases 1 item
  107. P110 1 item
  108. Hck 1 item
  109. GABAA Receptors 1 item
  110. Phospholipases 1 item
  111. TRP Channel 3item
  112. FoxM1 1 item
  113. M2 Receptors 1 item
  114. MNK 1 item
  115. Glucocorticoid Receptors 2item
  116. 15-lipoxygenases 1 item
  117. eEF-2 1 item
  118. Inward Rectifier Potassium (Kir) Channels 1 item
  119. Cdc7 1 item
  120. CMV 1 item
  121. ZAP-70 1 item
  122. Flk-1 1 item
  123. Antioxidants 1 item
  124. Cytidine deaminases 1 item
  125. angiogenesis 1 item
  126. Glucagon Receptors 1 item
  127. DPP-4 3item
  128. c-RET 2item
  129. p70 rsk 1 item
  130. FPTase 2item
  131. Microtubule/Tubulin 2item
  132. interleukin receptor 1 item
  133. Menin-MLL 2item
  134. Bfl-1 1 item
  135. sodium channels 1 item
  136. p53-MDM2 interaction 1 item
  137. KDR 2item
  138. Fyn kinase 1 item
  139. PARs 1 item
  140. p53 5item
  141. HDAC 1 item
  142. KDM 1 item
  143. c-Fms tyrosine kinase 1 item
  144. PAR 1 item
  145. cysteine protease 1 item
  146. STK 1 item
  147. HDM2 ubiquitin ligase 1 item
  148. USP1/USF1 complex 1 item
  149. IKK 1 item
  150. gp120-CD4 interaction 1 item
  151. HCV polymerase 3item
  152. Lyn kinase 1 item
  153. Ftase 1 item
  154. PC-PLC 1 item
  155. GK 1 item
  156. Antibiotic 1 item
  157. cannabinoid receptor 1 item
  158. DNA Alkylating 1 item
  159. Rev-Erb Receptors 1 item
  160. ErbB-2 1 item
  161. HIV 1 item
  162. sterol demethylase 1 item
  163. PDK-1 1 item
  164. GAPDH 1 item
  165. Histone Acetyltransferases (HATs) 2item
  166. Telomerases 1 item
  167. Prk 1 item
  168. Tyrosinases 1 item
  169. HSP70 1 item
  170. Aryl hydrocarbon receptors (AHRs) 1 item
  171. DCLK2 1 item
  172. phosphatidylinositol kinase 1 item
  173. Lck 1 item
  174. Adenosine Deaminases 1 item
  175. Thrombin Receptor 1 item
  176. DprE 1 item
  177. Flk1 2item
  178. p21 1 item
  179. Prostaglandin synthesis 1 item
  180. glutamate release 1 item
  181. PAFR 1 item
  182. Aromatases 1 item
  183. DHFR 1 item
  184. GARFT 1 item
  185. PHF 1 item
  186. UCH 1 item
  187. RHA 1 item
  188. HCV NS3-4A protease 1 item
  189. TRPC channel 1 item
  190. PKD 1 item
  191. Bcl-w 1 item
  192. NADH oxidase 1 item
  193. GLP-2 receptor 1 item
  194. SK 1 item
  195. MST 1 item
  196. PPK 1 item
  197. c-Syk 1 item
  198. CDK1/CyclinB 1 item
  199. Tph 1 item
  200. reverse transcriptase 1 item
  201. Vascular Disrupting Agents (VDA) 1 item
  202. Substance P/NK1 Receptor 1 item
  203. gp120/CD4 1 item
  204. Bax 1 item
  205. MTH1 1 item
  206. PTEN 1 item
  207. NS3/4a Proteases 1 item
  208. p90 S6K 1 item
Related Disease
  1. Acute Myeloid Leukemia 8item
  2. Acute Renal Failure 1 item
  3. Adrenocortical Carcinoma 1 item
  4. Anesthesia 1 item
  5. Biliary Cancer 1 item
  6. Bladder Cancer 2item
  7. Bladder Carcinoma 2item
  8. Bladder Diseases 1 item
  9. B-lymphoid Malignancies 1 item
  10. Breast Cancer 38item
  11. Cancer 128item
  12. Castration-resistant Prostate Cancer 1 item
  13. Cervical Cancer 4item
  14. Cholangiocarcinoma 1 item
  15. Chronic Lymphocytic Leukemia 2item
  16. Chronic Myeloproliferative Disorders 1 item
  17. Clear Cell Renal Cell Carcinoma 1 item
  18. Colon Cancer 7item
  19. Colon Carcinoma 2item
  20. Colorectal Cancer 12item
  21. Diabetes 2item
  22. Diffuse Large B-cell Lymphoma 1 item
  23. Epilepsy 1 item
  24. Fungi 1 item
  25. Glioblastoma 9item
  26. Glioma 3item
  27. HCV 3item
  28. Hepatitis C 2item
  29. Hepatocellular Carcinoma 2item
  30. HIV 5item
  31. HIV Infections 3item
  32. Inflammatory Diseases 3item
  33. Leukemia 5item
  34. Liver Cancer 3item
  35. Lung Cancer 8item
  36. Lymphoma 8item
  37. Mantle Cell Lymphoma 1 item
  38. Melanoma 7item
  39. Mixed Lineage Leukemia 1 item
  40. Multiple Myeloma 8item
  41. Myelofibrosis 2item
  42. Neuroblastoma 1 item
  43. Non-small Cell Lung Cancer 7item
  44. Ovarian Cancer 4item
  45. Pain Relief 1 item
  46. Pancreatic Cancer 11item
  47. Pancreatic Carcinoma 1 item
  48. Pentacyclic Triterpenoid 1 item
  49. Prostate Cancer 16item
  50. Psoriasis 1 item
  51. Pulmonary Fibrosis 2item
  52. Renal Cancer 1 item
  53. Rheumatoid Arthritis 4item
  54. Sarcoma 1 item
  55. Soft Tissue Sarcoma 1 item
  56. Squamous Cell Carcinoma 1 item
  57. Thyroid Cancer 2item
  58. Tuberculosis 1 item
  59. Type 2 Diabetes 3item