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Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

B5832 Altiratinib

1 Citation

Target: FLT3|VEGFR|Trk Receptors|c-MET|Tie-2

Summary: c-MET/TIE-2/VEGFR inhibitor

≥21.55 mg/mL
A3527 Ki20227

Target: c-Fms tyrosine kinase

Summary: C-Fms tyrosine kinase inhibitor

≥48.1 mg/mL
A5979 Tie2 kinase inhibitor

Target: Tie-2

Summary: Tie-2(Tie2 ) inhibitor

≥22 mg/mL
B5835 AZD2932

Target: FLT3|VEGFR|PDGFR|c-Kit

Summary: inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit

Soluble in DMSO
A2168 Dovitinib (TKI-258, CHIR-258)

2 Citation

Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR

Summary: Multitargeted RTK inhibitor

insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
A1882 Cediranib (AZD217)

Target: VEGFR

Summary: VEGFR inhibitor receptor,highly potent

≥22.52 mg/mL
B4899 BLZ945

1 Citation

Target: CSF-1R

Summary: CSF-1R kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.9 mg/mL
A3009 Sorafenib

2 Citation

Target: Raf|VEGFR

Summary: Raf kinases and tyrosine kinases inhibitor

≥23.25 mg/mL
B1438 BMS-794833

Target: MET|Flk-1

Summary: Met/VEGFR-2 inhibitor,potent and ATP-competitive

≥23.45 mg/mL
A8550 Telatinib (BAY 57-9352)

Target: VEGFR|PDGFR|c-Kit

Summary: VEGFR-2/-3,PDGFR-β and c-Kit inhibitor

insoluble in H2O; insoluble in EtOH; ≥20.5 mg/mL