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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 11-20 of 46

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  1. MIM1
    A4465 MIM1
     1 Citation
    Target: Mcl-1
    Summary: Mcl-1 Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥12.15 mg/mL
  2. Necrostatin 2
    A3652 Necrostatin 2
     2 Citation
    Summary: In vitro necroptosis inhibitor
      Soluble in DMSO
  3. WEHI-539 hydrochloride
    A8634 WEHI-539 hydrochloride
     1 Citation
    Summary: Bcl-xL inhibitor,high affinity and selective
      ≥28.55 mg/mL
  4. Pifithrin-μ
    A4482 Pifithrin-μ
     1 Citation
    Target: Autophagy|p53|HSP70
    Summary: Inhibitor of p53 binding and anti-apoptotic
      insoluble in H2O; ≥18.1 mg/mL
  5. PAC-1
    A8177 PAC-1
     1 Citation
    Target: Caspases
    Summary: Procaspase-3 activator
      insoluble in H2O; ≥13.4 mg/mL
  6. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  7. PRIMA-1
    A4483 PRIMA-1
    Target: p53
    Summary: BAX inhibitor
      ≥110.6 mg/mL
  8. JNJ-26854165 (Serdemetan)
    A4204 JNJ-26854165 (Serdemetan)
     1 Citation
    Target: p53|HDM2 ubiquitin ligase
    Summary: P53 activator, blocking Mdm2-p53 interaction
      insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
  9. Plumbagin
    A4456 Plumbagin
    Summary: Anticancer agent
  10. Matrine
    A3583 Matrine
    Summary: Alkaloid found in Sophora plant
      ≥12.42 mg/mL

Items 11-20 of 46

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  1. Category Apoptosis Remove This Item
  2. Reported Experiments Cell Experiments Remove This Item
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Category
  1. Caspase 8item
  2. Apoptosis Inducers 8item
  3. Bax 2item
  4. Bcl-2 Family 13item
  5. Bcl-xL 4item
  6. c-RET 3item
  7. IAP 1 item
  8. KEAP1-Nrf2 1 item
  9. MDM2 2item
  10. p53 8item
  11. PC-PLC 1 item
  12. PKD 1 item
  13. Thymidylate Synthase 1 item
  14. TNF-α 3item
Specificity
  1. Selective 23item
Reversibility
  1. Irreversible 6item
Target
  1. Caspases 7item
  2. Histone Deacetylases (HDACs) 1 item
  3. Inhibitor of apoptosis proteins (IAP) 1 item
  4. Bcl-2 8item
  5. Raf 2item
  6. Aurora Kinases 1 item
  7. Bcl-xl 3item
  8. MDM2 1 item
  9. VEGFR 2item
  10. PDGFR 3item
  11. c-Kit 2item
  12. RET 1 item
  13. Mcl-1 4item
  14. Thymidylate Synthase 1 item
  15. Bcr-Abl 1 item
  16. Nrf2 1 item
  17. Sir2-like Family Deacetylases (Sirtuins) 1 item
  18. Aminopeptidases 1 item
  19. Topoisomerases 1 item
  20. Autophagy 1 item
  21. TRP Channel 1 item
  22. angiogenesis 1 item
  23. c-RET 1 item
  24. FPTase 1 item
  25. Bfl-1 1 item
  26. p53-MDM2 interaction 1 item
  27. p53 5item
  28. cysteine protease 1 item
  29. HDM2 ubiquitin ligase 1 item
  30. PC-PLC 1 item
  31. HIV 1 item
  32. Histone Acetyltransferases (HATs) 1 item
  33. Telomerases 1 item
  34. Tyrosinases 1 item
  35. HSP70 1 item
  36. p21 1 item
  37. DHFR 1 item
  38. GARFT 1 item
  39. PKD 1 item
  40. Bcl-w 1 item
  41. Bax 1 item
  42. NS3/4a Proteases 1 item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Breast Cancer 4item
  3. Cancer 25item
  4. Chronic Lymphocytic Leukemia 1 item
  5. Chronic Myeloproliferative Disorders 1 item
  6. Colon Cancer 1 item
  7. Colorectal Cancer 1 item
  8. Glioblastoma 1 item
  9. HCV 1 item
  10. Lymphoma 3item
  11. Melanoma 1 item
  12. Multiple Myeloma 1 item
  13. Myelofibrosis 1 item
  14. Pain Relief 1 item
  15. Pancreatic Cancer 1 item
  16. Pentacyclic Triterpenoid 1 item
  17. Prostate Cancer 3item
  18. Pulmonary Fibrosis 1 item
  19. Soft Tissue Sarcoma 1 item