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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 61-70 of 122

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  1. BYK 49187
    A4526 BYK 49187
    Summary: Potent PARP-1/PARP-2 inhibitor
      <16.77 mg/mL
  2. OTX-015
    A3692 OTX-015
     3 Citation
    Target: Bromodomains
    Summary: BRD inhibitor
      ≥24.6 mg/mL
  3. XAV-939
    A1877 XAV-939
     1 Citation
    Target: TNKS
    Summary: Tankyrase 1/2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15.62 mg/mL
  4. ABC294640
    B1182 ABC294640
    Target: SK
    Summary: Sphingosine kinase 2 inhibitor,selective and competitive
      ≥38.1 mg/mL
  5. BMS-345541(free base)
    B4655 BMS-345541(free base)
    Summary: IKK-1/IKK-2 inhibitor,potent and selective
      insoluble in H2O; ≥70 mg/mL
  6. CYT387
    A4143 CYT387
     1 Citation
    Summary: JAK-1/-2 inhibitor,ATP competitive
      insoluble in EtOH; insoluble in H2O; ≥20.7 mg/mL
  7. Veliparib dihydrochloride
    A3958 Veliparib dihydrochloride
    Target: PARP
    Summary: PARP-1/PARP-2 inhibitor
      ≥31.7 mg/mL
  8. Mocetinostat (MGCD0103, MG0103)
    A4089 Mocetinostat (MGCD0103, MG0103)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,isotype-selective and potent
      insoluble in EtOH; insoluble in H2O; ≥19.8 mg/mL
  9. PTP Inhibitor I
    C3607 PTP Inhibitor I
    Summary: tyrosine phosphatase (PTP) inhibitor
      insoluble in H2O; ≥11.5 mg/mL
  10. AZD1480
    A4137 AZD1480
    Target: JAK
    Summary: JAK2 inhibitor,ATP-competitive and novel
      insoluble in H2O; ≥93.8 mg/mL

Items 61-70 of 122

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  1. Category Chromatin/Epigenetics Remove This Item
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  1. Bromodomain 7item
  2. Aurora Kinase 13item
  3. DNA Methyltransferase 4item
  4. HDAC 16item
  5. Histone Acetyltransferases 3item
  6. Histone Demethylases 3item
  7. Histone Methyltransferase 15item
  8. HIF 4item
  9. JAK 19item
  10. PARP 17item
  11. Pim 6item
  12. Protein Ser/Thr Phosphatases 10item
  13. Sirtuin 3item
  14. Sphingosine Kinase-2 1 item
  15. Polycomb repressive complex 1 item
  16. SUMOylation 1 item
Specificity
  1. Selective 43item
Reversibility
  1. Reversible 3item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 12item
  3. PI3K 1 item
  4. Aurora Kinases 8item
  5. EZH2 2item
  6. Bromodomains 4item
  7. FLT3 1 item
  8. PLK 1 item
  9. MEK 1 item
  10. DOT1L 1 item
  11. FGFR 1 item
  12. Pim 1 item
  13. Sir2-like Family Deacetylases (Sirtuins) 1 item
  14. Src 1 item
  15. STAT 2item
  16. JAK 12item
  17. EZH1 1 item
  18. TNKS 1 item
  19. DNA Methyltransferases 2item
  20. SMYD2 1 item
  21. PARP 5item
  22. phosphatases 1 item
  23. G9a 1 item
  24. SETD7 1 item
  25. MNK 1 item
  26. Cytidine deaminases 1 item
  27. c-RET 1 item
  28. p53 1 item
  29. HDAC 1 item
  30. KDM 1 item
  31. Histone Acetyltransferases (HATs) 1 item
  32. Lck 1 item
  33. p21 1 item
  34. PHF 1 item
  35. SK 1 item
Reported Experiments
  1. Animal Experiments 47item
  2. Cell Experiments 39item
Related Disease
  1. Acute Myeloid Leukemia 3item
  2. Bladder Carcinoma 1 item
  3. Breast Cancer 10item
  4. Cancer 34item
  5. Castration-resistant Prostate Cancer 1 item
  6. Cervical Cancer 2item
  7. Colon Cancer 5item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 1 item
  10. Diabetes 1 item
  11. Diffuse Large B-cell Lymphoma 1 item
  12. Glioblastoma 1 item
  13. Glioma 2item
  14. Hepatocellular Carcinoma 1 item
  15. HIV 2item
  16. HIV Infections 1 item
  17. Immunological Diseases 1 item
  18. Inflammatory Bowel Disease 1 item
  19. Inflammatory Diseases 2item
  20. Leukemia 3item
  21. Lung Cancer 3item
  22. Lymphoma 1 item
  23. Melanoma 1 item
  24. Mixed Lineage Leukemia 1 item
  25. Multiple Myeloma 3item
  26. Myelofibrosis 1 item
  27. Myeloma 1 item
  28. Non-small Cell Lung Cancer 3item
  29. Ovarian Cancer 1 item
  30. Pancreatic Cancer 2item
  31. Prostate Cancer 6item
  32. Psoriasis 1 item
  33. Renal Cell Carcinoma 1 item
  34. Rheumatoid Arthritis 3item