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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 71-80 of 122

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  1. PCI-34051
    A4091 PCI-34051
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC8 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥14.8 mg/mL
  2. GSK 525768A
    A3445 GSK 525768A
    Summary: inactive stereoisomer of I-BET-762
      Soluble in DMSO
  3. PJ34
    A3729 PJ34
    Target: PARP
    Summary: PARP-l inhibitor
      ≥50.9 mg/mL
  4. Bromodomain Inhibitor, (+)-JQ1
    A1910 Bromodomain Inhibitor, (+)-JQ1
     38 Citation
    Target: Bromodomains
    Summary: BET bromodomain inhibitor
      ≥22.85 mg/mL
  5. PJ34 hydrochloride
    A4159 PJ34 hydrochloride
    Summary: PARP inhibitor,potent and cell-permeable
      insoluble in H2O; insoluble in EtOH; ≥16.6 mg/mL
  6. Vorinostat (SAHA, MK0683)
    A4084 Vorinostat (SAHA, MK0683)
     9 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in EtOH; insoluble in H2O; ≥4.41 mg/mL
  7. SGI-1776 free base
    A4192 SGI-1776 free base
     3 Citation
    Summary: Pim kinase inhibitor,ATP-competitive
      ≥40.5 mg/mL
  8. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL
  9. 1,2,3,4,5,6-Hexabromocyclohexane
    A4510 1,2,3,4,5,6-Hexabromocyclohexane
    Summary: JAK2 tyrosine kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥8.22 mg/mL
  10. Zebularine
    A1915 Zebularine
     1 Citation
    Target: DNA Methyltransferases|Cytidine deaminases
    Summary: DNA methylation inhibitor
      insoluble in EtOH; ≥50.7 mg/mL

Items 71-80 of 122

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  1. Category Chromatin/Epigenetics Remove This Item
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  1. Bromodomain 7item
  2. Aurora Kinase 13item
  3. DNA Methyltransferase 4item
  4. HDAC 16item
  5. Histone Acetyltransferases 3item
  6. Histone Demethylases 3item
  7. Histone Methyltransferase 15item
  8. HIF 4item
  9. JAK 19item
  10. PARP 17item
  11. Pim 6item
  12. Protein Ser/Thr Phosphatases 10item
  13. Sirtuin 3item
  14. Sphingosine Kinase-2 1 item
  15. Polycomb repressive complex 1 item
  16. SUMOylation 1 item
Specificity
  1. Selective 43item
Reversibility
  1. Reversible 3item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 12item
  3. PI3K 1 item
  4. Aurora Kinases 8item
  5. EZH2 2item
  6. Bromodomains 4item
  7. FLT3 1 item
  8. PLK 1 item
  9. MEK 1 item
  10. DOT1L 1 item
  11. FGFR 1 item
  12. Pim 1 item
  13. Sir2-like Family Deacetylases (Sirtuins) 1 item
  14. Src 1 item
  15. STAT 2item
  16. JAK 12item
  17. EZH1 1 item
  18. TNKS 1 item
  19. DNA Methyltransferases 2item
  20. SMYD2 1 item
  21. PARP 5item
  22. phosphatases 1 item
  23. G9a 1 item
  24. SETD7 1 item
  25. MNK 1 item
  26. Cytidine deaminases 1 item
  27. c-RET 1 item
  28. p53 1 item
  29. HDAC 1 item
  30. KDM 1 item
  31. Histone Acetyltransferases (HATs) 1 item
  32. Lck 1 item
  33. p21 1 item
  34. PHF 1 item
  35. SK 1 item
Reported Experiments
  1. Animal Experiments 47item
  2. Cell Experiments 39item
Related Disease
  1. Acute Myeloid Leukemia 3item
  2. Bladder Carcinoma 1 item
  3. Breast Cancer 10item
  4. Cancer 34item
  5. Castration-resistant Prostate Cancer 1 item
  6. Cervical Cancer 2item
  7. Colon Cancer 5item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 1 item
  10. Diabetes 1 item
  11. Diffuse Large B-cell Lymphoma 1 item
  12. Glioblastoma 1 item
  13. Glioma 2item
  14. Hepatocellular Carcinoma 1 item
  15. HIV 2item
  16. HIV Infections 1 item
  17. Immunological Diseases 1 item
  18. Inflammatory Bowel Disease 1 item
  19. Inflammatory Diseases 2item
  20. Leukemia 3item
  21. Lung Cancer 3item
  22. Lymphoma 1 item
  23. Melanoma 1 item
  24. Mixed Lineage Leukemia 1 item
  25. Multiple Myeloma 3item
  26. Myelofibrosis 1 item
  27. Myeloma 1 item
  28. Non-small Cell Lung Cancer 3item
  29. Ovarian Cancer 1 item
  30. Pancreatic Cancer 2item
  31. Prostate Cancer 6item
  32. Psoriasis 1 item
  33. Renal Cell Carcinoma 1 item
  34. Rheumatoid Arthritis 3item