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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 1-10 of 47

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  1. Apicidin
    A8176 Apicidin
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Potent HDAC inhibitor
      soluble in DMSO or ethanol
  2. Danusertib (PHA-739358)
    A4116 Danusertib (PHA-739358)
     2 Citation
    Target: Aurora Kinases
    Summary: Pan-aurora kinase inhibitor
      ≥23.75 mg/mL
  3. Tenovin-1
    A4203 Tenovin-1
    Target: Sir2-like Family Deacetylases (Sirtuins)|p53|p21
    Summary: SIRT2 inhibitor, activates p53
      insoluble in H2O; insoluble in EtOH; ≥15 mg/mL
  4. I-BET-762
    B1498 I-BET-762
     4 Citation
    Target: Bromodomains
    Summary: BET inhibitor,highly potent
      ≥21.19 mg/mL
  5. Entinostat (MS-275,SNDX-275)
    A8171 Entinostat (MS-275,SNDX-275)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1 and HDAC3 inhibitor
      insoluble in H2O; ≥18.8 mg/mL
  6. BMS-911543
    A4152 BMS-911543
    Target: JAK
    Summary: JAK2 inhibitor,selective small molecule
      ≥43.3 mg/mL
  7. TG101348 (SAR302503)
    A4136 TG101348 (SAR302503)
     2 Citation
    Target: FLT3|JAK|c-RET
    Summary: JAK-2 inhibitor,potent and selective
      ≥26.23 mg/mL
  8. NSC 3852
    A4496 NSC 3852
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in EtOH; insoluble in H2O; ≥7.35 mg/mL
  9. TC-A 2317 hydrochloride
    A4489 TC-A 2317 hydrochloride
    Target: Aurora Kinases
    Summary: Aurora kinase A inhibitor,potent and selective
      <39.29 mg/mL
  10. Tofacitinib (CP-690550,Tasocitinib)
    A4138 Tofacitinib (CP-690550,Tasocitinib)
     1 Citation
    Target: JAK
    Summary: Janus kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥15.6 mg/mL

Items 1-10 of 47

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Category
  1. Bromodomain 4item
  2. Aurora Kinase 6item
  3. DNA Methyltransferase 2item
  4. HDAC 13item
  5. Histone Demethylases 1 item
  6. Histone Methyltransferase 3item
  7. JAK 10item
  8. PARP 5item
  9. Pim 1 item
  10. Protein Ser/Thr Phosphatases 1 item
  11. Sirtuin 1 item
  12. Sphingosine Kinase-2 1 item
Specificity
  1. Selective 32item
Reversibility
  1. Reversible 2item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 11item
  3. PI3K 1 item
  4. Aurora Kinases 6item
  5. EZH2 1 item
  6. Bromodomains 4item
  7. FLT3 1 item
  8. PLK 1 item
  9. DOT1L 1 item
  10. FGFR 1 item
  11. Pim 1 item
  12. Sir2-like Family Deacetylases (Sirtuins) 1 item
  13. STAT 2item
  14. JAK 10item
  15. EZH1 1 item
  16. TNKS 1 item
  17. DNA Methyltransferases 2item
  18. PARP 4item
  19. phosphatases 1 item
  20. MNK 1 item
  21. Cytidine deaminases 1 item
  22. c-RET 1 item
  23. p53 1 item
  24. HDAC 1 item
  25. p21 1 item
  26. SK 1 item
Related Disease
  1. Acute Myeloid Leukemia 3item
  2. Bladder Carcinoma 1 item
  3. Breast Cancer 9item
  4. Cancer 31item
  5. Castration-resistant Prostate Cancer 1 item
  6. Cervical Cancer 2item
  7. Colon Cancer 5item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 1 item
  10. Diffuse Large B-cell Lymphoma 1 item
  11. Glioblastoma 1 item
  12. Glioma 2item
  13. Hepatocellular Carcinoma 1 item
  14. HIV 2item
  15. HIV Infections 1 item
  16. Immunological Diseases 1 item
  17. Inflammatory Bowel Disease 1 item
  18. Inflammatory Diseases 2item
  19. Leukemia 3item
  20. Lung Cancer 3item
  21. Mixed Lineage Leukemia 1 item
  22. Multiple Myeloma 3item
  23. Myelofibrosis 1 item
  24. Myeloma 1 item
  25. Non-small Cell Lung Cancer 3item
  26. Ovarian Cancer 1 item
  27. Pancreatic Cancer 2item
  28. Prostate Cancer 5item
  29. Psoriasis 1 item
  30. Renal Cell Carcinoma 1 item
  31. Rheumatoid Arthritis 3item