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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 11-20 of 133

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  1. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  2. PRIMA-1
    A4483 PRIMA-1
    Target: p53
    Summary: BAX inhibitor
      ≥110.6 mg/mL
  3. JNJ-26854165 (Serdemetan)
    A4204 JNJ-26854165 (Serdemetan)
     1 Citation
    Target: p53|HDM2 ubiquitin ligase
    Summary: P53 activator, blocking Mdm2-p53 interaction
      insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
  4. Plumbagin
    A4456 Plumbagin
    Summary: Anticancer agent
  5. Matrine
    A3583 Matrine
    Summary: Alkaloid found in Sophora plant
      ≥12.42 mg/mL
  6. Z-IETD-FMK
    B3232 Z-IETD-FMK
     12 Citation
    Target: Caspases
    Summary: Caspase-8 inhibitor
      ≥32.73 mg/mL
  7. 4E1RCat
    B3697 4E1RCat
    Target: eIF4F
    Summary: Dual inhibitor of eIF4E:eIF4G and eIF4E:4E-BP1 interaction
      ≥23.85 mg/mL
  8. Q-VD-OPh
    A1901 Q-VD-OPh
     53 Citation
    Target: Caspases
    Summary: Cell-permeable, irreversible pan-caspase inhibitor
      ≥25.67 mg/mL
  9. Danusertib (PHA-739358)
    A4116 Danusertib (PHA-739358)
     2 Citation
    Target: Aurora Kinases
    Summary: Pan-aurora kinase inhibitor
      ≥23.75 mg/mL
  10. Lenalidomide (CC-5013)
    A4211 Lenalidomide (CC-5013)
    Target: angiogenesis
    Summary: Antineoplastic agent,inhibits angiogenesis
      insoluble in EtOH; insoluble in H2O; ≥100.8 mg/mL

Items 11-20 of 133

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  1. Signaling Pathways 128item
  2. Natural Products 3item
  3. Lab Reagents 1 item
Specificity
  1. Selective 87item
Reversibility
  1. Reversible 9item
  2. Irreversible 5item
Target
  1. Caspases 3item
  2. Cyclin-Dependent Kinases 8item
  3. Proteasome 1 item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 4item
  6. Akt 4item
  7. Bcl-2 7item
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  9. Raf 4item
  10. Aurora Kinases 4item
  11. Bcl-xl 2item
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  23. Chk 1 item
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  25. VEGFR 17item
  26. PDGFR 7item
  27. c-Kit 4item
  28. RET 1 item
  29. Phosphodiesterases (PDEs) 1 item
  30. Mcl-1 3item
  31. Thymidylate Synthase 1 item
  32. Bcr-Abl 3item
  33. MEK 4item
  34. DOT1L 1 item
  35. FGFR 3item
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  37. Src 2item
  38. RARs 1 item
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  40. STAT 2item
  41. EGFR 5item
  42. FAK 2item
  43. JAK 6item
  44. EZH1 1 item
  45. DNA-PK 1 item
  46. HSP90 2item
  47. Cytochrome P450 (CYP450) 1 item
  48. ErbB 1 item
  49. DNA Methyltransferases 1 item
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  51. c-MET 2item
  52. PKC 3item
  53. Pyk2 2item
  54. Insulin and Insulin-like Receptors 1 item
  55. PARP 2item
  56. Pyruvate dehydrogenases (PDH) 1 item
  57. ALK 1 item
  58. PKG 1 item
  59. PKA 4item
  60. AdipoR2 1 item
  61. MK2 1 item
  62. Tie-2 2item
  63. RSK 1 item
  64. Autophagy 1 item
  65. COX 2item
  66. Guanine nucleotide exchange factors (GEFs) 1 item
  67. 20S proteasomal chymotrypsin 1 item
  68. Geranylgeranyltransferase I 1 item
  69. Farnesyltransferase 1 item
  70. Nampt 1 item
  71. eIF4F 1 item
  72. Glutaminases 1 item
  73. MAGL 1 item
  74. P110 1 item
  75. Hck 1 item
  76. Opioid receptors 1 item
  77. FoxM1 1 item
  78. MNK 1 item
  79. eEF-2 1 item
  80. Cdc7 1 item
  81. CMV 1 item
  82. ZAP-70 1 item
  83. Hexokinases 1 item
  84. Flk-1 1 item
  85. Cytidine deaminases 1 item
  86. angiogenesis 1 item
  87. c-RET 1 item
  88. p70 rsk 1 item
  89. Microtubule/Tubulin 1 item
  90. Bfl-1 1 item
  91. p53-MDM2 interaction 1 item
  92. KDR 2item
  93. p53 3item
  94. HDAC 1 item
  95. HDM2 ubiquitin ligase 1 item
  96. DNA Alkylating 1 item
  97. ErbB-2 1 item
  98. PDK-1 1 item
  99. Prk 1 item
  100. HSP70 1 item
  101. Flk1 2item
  102. DHFR 1 item
  103. GARFT 1 item
  104. RHA 1 item
  105. Bcl-w 1 item
  106. SK 1 item
  107. PPK 1 item
  108. c-Syk 1 item
  109. CDK1/CyclinB 1 item
  110. Substance P/NK1 Receptor 1 item
  111. Bax 1 item