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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 21-30 of 414

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  1. PAC-1
    A8177 PAC-1
     1 Citation
    Target: Caspases
    Summary: Procaspase-3 activator
      insoluble in H2O; ≥13.4 mg/mL
  2. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  3. PRIMA-1
    A4483 PRIMA-1
    Target: p53
    Summary: BAX inhibitor
      ≥110.6 mg/mL
  4. Nicotine
    N2703 Nicotine
    Target: Voltage-gated Potassium (KV) Channels|AChR
  5. XMU-MP-1
    A8735 XMU-MP-1
     2 Citation
    Target: MST
    Summary: MST1/2 inhibitor, potent and selective
      ≥41.6 mg/mL
  6. Nutlin-3
    A4228 Nutlin-3
    Target: MDM2
    Summary: MDM2 antagonist,inhibits MDM2-p53 interaction
      ≥58.2 mg/mL
  7. GDC-0152
    A4224 GDC-0152
     2 Citation
    Target: Inhibitor of apoptosis proteins (IAP)
    Summary: IAP antagonist,potent amd samll-molecule
      ≥24.95 mg/mL
  8. JNJ-26854165 (Serdemetan)
    A4204 JNJ-26854165 (Serdemetan)
     1 Citation
    Target: p53|HDM2 ubiquitin ligase
    Summary: P53 activator, blocking Mdm2-p53 interaction
      insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
  9. LCL161
    A3541 LCL161
     1 Citation
    Target: Inhibitor of apoptosis proteins (IAP)
    Summary: Antagonist of IAPs inhibitor
      ≥25.05 mg/mL
  10. VX-765
    A8238 VX-765
     1 Citation
    Target: Caspases
    Summary: Caspase-1 inhibitor,potent and selective
      insoluble in H2O; ≥313 mg/mL

Items 21-30 of 414

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  1. Signaling Pathways 393item
  2. Natural Products 12item
  3. Probes & Dyes 1 item
  4. Lab Reagents 7item
Specificity
  1. Selective 274item
Reversibility
  1. Reversible 25item
  2. Irreversible 15item
Target
  1. Caspases 8item
  2. Cyclin-Dependent Kinases 11item
  3. Adenosine A2A Receptors 2item
  4. Proteasome 3item
  5. Cathepsins 3item
  6. Histone Deacetylases (HDACs) 12item
  7. Inhibitor of apoptosis proteins (IAP) 3item
  8. Akt 5item
  9. Bcl-2 8item
  10. PI3K 5item
  11. CXCR 3item
  12. Raf 6item
  13. Aurora Kinases 6item
  14. Bcl-xl 2item
  15. CSF-1R 1 item
  16. MDM2 2item
  17. EZH2 2item
  18. mTOR 7item
  19. Bromodomains 4item
  20. AP-1 2item
  21. MMP 4item
  22. Androgen Receptors 1 item
  23. Myosin II ATPases 1 item
  24. DT-diaphorases 1 item
  25. Voltage-gated Potassium (KV) Channels 1 item
  26. FLT3 5item
  27. GSK-3 2item
  28. Factor Xa 1 item
  29. Farnesoid X receptors (FXRs) 1 item
  30. P-glycoprotein (P-gp) 1 item
  31. PLK 4item
  32. Chk 2item
  33. Eph Receptors 2item
  34. VEGFR 28item
  35. PDGFR 10item
  36. c-Kit 6item
  37. RET 2item
  38. Phosphodiesterases (PDEs) 3item
  39. Mcl-1 3item
  40. Thymidylate Synthase 1 item
  41. p38 2item
  42. PKB 1 item
  43. JNK 1 item
  44. Bcr-Abl 3item
  45. MEK 8item
  46. DOT1L 1 item
  47. FGFR 8item
  48. Nrf2 1 item
  49. Pim 1 item
  50. Sir2-like Family Deacetylases (Sirtuins) 1 item
  51. Voltage-gated Sodium (NaV) Channels 2item
  52. Deubiquitinating enzymes (DUBs) 1 item
  53. Smoothened 1 item
  54. MET 4item
  55. Src 4item
  56. RARs 1 item
  57. Trk Receptors 2item
  58. Aminopeptidases 3item
  59. STAT 2item
  60. Microtubules/Tubulins 1 item
  61. Estrogen and Related Receptors 3item
  62. EGFR 11item
  63. Hedgehog 1 item
  64. Reverse Transcriptases 1 item
  65. ROCK 1 item
  66. BTK 1 item
  67. RIP kinases 1 item
  68. Monocyte chemotactic proteins 1 item
  69. PAK 1 item
  70. Hypoxia Inducible Factors (HIFs) 1 item
  71. FAK 3item
  72. BMP and Other Activin Receptors 2item
  73. JAK 11item
  74. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  75. Syk 1 item
  76. EZH1 2item
  77. DNA-PK 2item
  78. HSP90 4item
  79. AMPK 1 item
  80. PDHK 1 item
  81. CFTR 1 item
  82. TNKS 1 item
  83. Topoisomerases 1 item
  84. Cytochrome P450 (CYP450) 6item
  85. M3 Receptors 1 item
  86. Ksp 2item
  87. Renin 1 item
  88. ErbB 2item
  89. S6 kinases 1 item
  90. Toll-like receptors (TLRs) 1 item
  91. Serine Proteases 1 item
  92. DNA Methyltransferases 2item
  93. Survivin 1 item
  94. ERK 2item
  95. c-MET 2item
  96. PKC 3item
  97. Ubiquitin-specific proteases 1 item
  98. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  99. SGLT 2item
  100. RAD51 1 item
  101. HER2 1 item
  102. Pyk2 3item
  103. 5-HT2 Receptors 3item
  104. LRRK2 4item
  105. Voltage-gated Calcium Channels (CaV) 1 item
  106. Insulin and Insulin-like Receptors 3item
  107. PARP 4item
  108. Melanocortin (MC) Receptors 1 item
  109. Pyruvate dehydrogenases (PDH) 1 item
  110. ALK 2item
  111. Sphingosine kinases (SphKs) 1 item
  112. Dehydrogenase 1 item
  113. PKG 1 item
  114. PKA 4item
  115. D1 and D5 Receptors 3item
  116. D2 Receptors 3item
  117. D3 Receptors 1 item
  118. 5-HT1 Receptors 2item
  119. 5-HT7 Receptors 1 item
  120. AdipoR2 1 item
  121. AMPA 1 item
  122. MK2 2item
  123. Fatty-acid-binding proteins (FABPs) 1 item
  124. Tie-2 3item
  125. RSK 1 item
  126. Free Fatty Acid Receptors 1 item
  127. phosphatases 3item
  128. Autophagy 1 item
  129. ATM/ATR 1 item
  130. COX 10item
  131. Folate Analogue 1 item
  132. CK2 1 item
  133. Guanine nucleotide exchange factors (GEFs) 1 item
  134. 20S proteasomal chymotrypsin 1 item
  135. Geranylgeranyltransferase I 1 item
  136. Farnesyltransferase 1 item
  137. Nampt 1 item
  138. eIF4F 1 item
  139. Glutaminases 1 item
  140. HSV 1 item
  141. NADPH Oxidases 2item
  142. Calcium-activated chloride channels (CaCC) 1 item
  143. GPR35 1 item
  144. MAGL 1 item
  145. Histamine H1 Receptors 3item
  146. Na /K ATPases 1 item
  147. P110 1 item
  148. Hck 1 item
  149. GABAA Receptors 1 item
  150. Opioid receptors 1 item
  151. Phospholipases 1 item
  152. TRP Channel 3item
  153. FoxM1 1 item
  154. M2 Receptors 1 item
  155. MNK 1 item
  156. Glucocorticoid Receptors 2item
  157. Adenosine A1 Receptors 1 item
  158. 15-lipoxygenases 1 item
  159. eEF-2 1 item
  160. Inward Rectifier Potassium (Kir) Channels 1 item
  161. Cdc7 1 item
  162. CMV 1 item
  163. ZAP-70 1 item
  164. Hexokinases 1 item
  165. Flk-1 1 item
  166. Antioxidants 2item
  167. Cytidine deaminases 1 item
  168. angiogenesis 1 item
  169. Glucagon Receptors 1 item
  170. DPP-4 3item
  171. c-RET 2item
  172. p70 rsk 1 item
  173. FPTase 2item
  174. AChR 1 item
  175. Microtubule/Tubulin 2item
  176. interleukin receptor 1 item
  177. Bfl-1 1 item
  178. p53-MDM2 interaction 1 item
  179. KDR 2item
  180. Fyn kinase 1 item
  181. PARs 1 item
  182. p53 5item
  183. HDAC 1 item
  184. c-Fms tyrosine kinase 1 item
  185. PAR 1 item
  186. cysteine protease 1 item
  187. HDM2 ubiquitin ligase 1 item
  188. IKK 1 item
  189. gp120-CD4 interaction 1 item
  190. HCV polymerase 2item
  191. Lyn kinase 1 item
  192. Ftase 1 item
  193. PC-PLC 1 item
  194. GK 1 item
  195. Glucosidases 1 item
  196. Antibiotic 1 item
  197. cannabinoid receptor 1 item
  198. DNA Alkylating 1 item
  199. Rev-Erb Receptors 1 item
  200. ErbB-2 1 item
  201. HIV 1 item
  202. sterol demethylase 1 item
  203. PDK-1 1 item
  204. GAPDH 1 item
  205. Histone Acetyltransferases (HATs) 1 item
  206. Telomerases 1 item
  207. Prk 1 item
  208. Tyrosinases 1 item
  209. HSP70 1 item
  210. Aryl hydrocarbon receptors (AHRs) 1 item
  211. DCLK2 1 item
  212. phosphatidylinositol kinase 1 item
  213. Adenosine Deaminases 1 item
  214. Thrombin Receptor 1 item
  215. UCP 1 item
  216. DprE 1 item
  217. Flk1 2item
  218. p21 1 item
  219. Prostaglandin synthesis 1 item
  220. glutamate release 1 item
  221. PAFR 1 item
  222. Aromatases 1 item
  223. DHFR 1 item
  224. GARFT 1 item
  225. UCH 1 item
  226. RHA 1 item
  227. HCV NS3-4A protease 1 item
  228. TRPC channel 1 item
  229. PKD 1 item
  230. Pyruvate kinases 1 item
  231. Bcl-w 1 item
  232. SK 1 item
  233. MST 1 item
  234. PPK 1 item
  235. c-Syk 1 item
  236. CDK1/CyclinB 1 item
  237. Tph 1 item
  238. reverse transcriptase 1 item
  239. GLP-1 receptor 1 item
  240. Vascular Disrupting Agents (VDA) 1 item
  241. Substance P/NK1 Receptor 1 item
  242. gp120/CD4 1 item
  243. Bax 1 item
  244. Somatostatin Receptors 1 item
  245. MTH1 1 item
  246. PTEN 1 item
  247. NS3/4a Proteases 1 item
  248. p90 S6K 1 item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acute Disseminated Candidiasis 1 item
  3. Acute Myeloid Leukemia 9item
  4. Acute Renal Failure 1 item
  5. Adrenocortical Carcinoma 2item
  6. Advanced Renal Cell Carcinoma 1 item
  7. Anesthesia 1 item
  8. Autoimmune Diseases 1 item
  9. Biliary Cancer 1 item
  10. Bladder Cancer 3item
  11. Bladder Carcinoma 2item
  12. Bladder Diseases 1 item
  13. B-lymphoid Malignancies 1 item
  14. Breast Cancer 66item
  15. Cancer 202item
  16. Candida Peritonitis 1 item
  17. Candidemia 1 item
  18. Castration-resistant Prostate Cancer 1 item
  19. Cervical Cancer 6item
  20. Cholangiocarcinoma 1 item
  21. Chronic Lymphocytic Leukemia 3item
  22. Chronic Myeloproliferative Disorders 1 item
  23. Clear Cell Renal Cell Carcinoma 1 item
  24. Colon Cancer 16item
  25. Colon Carcinoma 4item
  26. Colorectal Cancer 20item
  27. Diabetes 4item
  28. Diffuse Large B-cell Lymphoma 1 item
  29. Epilepsy 1 item
  30. Fungal Infection 2item
  31. Fungi 1 item
  32. Glioblastoma 16item
  33. Glioma 6item
  34. HCV 2item
  35. Hepatitis C 2item
  36. Hepatocellular Carcinoma 4item
  37. HIV 6item
  38. HIV Infections 3item
  39. Immunological Diseases 1 item
  40. Immunosuppressive Therapy 1 item
  41. Inflammatory Bowel Disease 1 item
  42. Inflammatory Diseases 13item
  43. Leukemia 8item
  44. Liver Cancer 4item
  45. Lung Cancer 20item
  46. Lung Carcinoma 1 item
  47. Lymphoma 9item
  48. Mantle Cell Lymphoma 1 item
  49. Melanoma 15item
  50. Mixed Lineage Leukemia 1 item
  51. Multiple Myeloma 11item
  52. Myelofibrosis 2item
  53. Myeloma 2item
  54. Neuroblastoma 2item
  55. Non-small Cell Lung Cancer 13item
  56. Ovarian Cancer 11item
  57. Pain Relief 1 item
  58. Pancreatic Cancer 22item
  59. Pancreatic Carcinoma 2item
  60. Pentacyclic Triterpenoid 1 item
  61. Prostate Cancer 26item
  62. Psoriasis 2item
  63. Pulmonary Fibrosis 2item
  64. Renal Cancer 2item
  65. Renal Cell Carcinoma 4item
  66. Rheumatoid Arthritis 7item
  67. Sarcoma 1 item
  68. Schizophrenia 3item
  69. Soft Tissue Sarcoma 1 item
  70. Squamous Cell Carcinoma 1 item
  71. Testicular Cancer 1 item
  72. Thyroid Cancer 3item
  73. Tuberculosis 1 item
  74. Type 2 Diabetes 7item