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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

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  1. ABT-263 (Navitoclax)
    A3007 ABT-263 (Navitoclax)
     15 Citation
    Target: Bcl-2|Bcl-w
    Summary: Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w
      ≥48.73 mg/mL
  2. Obatoclax mesylate (GX15-070)
    A4194 Obatoclax mesylate (GX15-070)
     1 Citation
    Target: Bcl-2
    Summary: Potent Bcl-2 inhibitor
      insoluble in H2O; ≥20.7 mg/mL
  3. Sabutoclax
    A4199 Sabutoclax
     2 Citation
    Target: Bcl-2|Mcl-1|Bfl-1
    Summary: pan-Bcl-2 inhibitor
      insoluble in H2O; ≥205.6 mg/mL
  4. TW-37
    A4234 TW-37
     1 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1
      insoluble in H2O; ≥19.75 mg/mL
  5. HA14-1
    A8168 HA14-1
    Target: Bcl-2
    Summary: Bcl-2 inhibitor,potent and cell-permeable
      insoluble in H2O; ≥20.45 mg/mL
  6. Apogossypolone (ApoG2)
    A4200 Apogossypolone (ApoG2)
     2 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor,nonpeptidic small molecule
      ≥24.55 mg/mL
  7. Bax inhibitor peptide V5
    A4461 Bax inhibitor peptide V5
    Target: Bax
    Summary: Bax inhibitor
      ≥29.35 mg/mL
  8. PHA-767491
    A3721 PHA-767491
    Target: Cyclin-Dependent Kinases|MK2|Cdc7
    Summary: Cdc7/cdk9 inhibitor, potent, ATP-competitive
      insoluble in H2O; insoluble in EtOH; ≥10.65 mg/mL
  9. RI-2
    B5881 RI-2
    Target: RAD51
    Summary: Optimized reversible RAD51 inhibitor
      ≥21.65 mg/mL
  10. YM155
    A4221 YM155
     2 Citation
    Target: Survivin
    Summary: Survivin suppressant,apoptosis inhibitor
      ≥22.15 mg/mL

Items 1-10 of 202

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  1. Signaling Pathways 197item
  2. Natural Products 3item
  3. Lab Reagents 1 item
Specificity
  1. Selective 153item
Reversibility
  1. Reversible 15item
  2. Irreversible 7item
Target
  1. Caspases 3item
  2. Cyclin-Dependent Kinases 10item
  3. Proteasome 2item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 10item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 5item
  8. Bcl-2 7item
  9. PI3K 4item
  10. CXCR 1 item
  11. Raf 6item
  12. Aurora Kinases 4item
  13. Bcl-xl 2item
  14. CSF-1R 1 item
  15. MDM2 2item
  16. EZH2 1 item
  17. mTOR 5item
  18. Bromodomains 2item
  19. AP-1 1 item
  20. MMP 2item
  21. Androgen Receptors 1 item
  22. DT-diaphorases 1 item
  23. FLT3 3item
  24. GSK-3 2item
  25. P-glycoprotein (P-gp) 1 item
  26. PLK 3item
  27. Chk 2item
  28. Eph Receptors 2item
  29. VEGFR 25item
  30. PDGFR 9item
  31. c-Kit 5item
  32. RET 2item
  33. Phosphodiesterases (PDEs) 1 item
  34. Mcl-1 3item
  35. Thymidylate Synthase 1 item
  36. JNK 1 item
  37. Bcr-Abl 3item
  38. MEK 7item
  39. DOT1L 1 item
  40. FGFR 5item
  41. Deubiquitinating enzymes (DUBs) 1 item
  42. Smoothened 1 item
  43. MET 4item
  44. Src 3item
  45. RARs 1 item
  46. Trk Receptors 1 item
  47. Aminopeptidases 1 item
  48. STAT 2item
  49. Microtubules/Tubulins 1 item
  50. Estrogen and Related Receptors 1 item
  51. EGFR 9item
  52. Hedgehog 1 item
  53. PAK 1 item
  54. FAK 3item
  55. BMP and Other Activin Receptors 1 item
  56. JAK 7item
  57. Syk 1 item
  58. EZH1 1 item
  59. DNA-PK 1 item
  60. HSP90 4item
  61. TNKS 1 item
  62. Cytochrome P450 (CYP450) 2item
  63. Ksp 1 item
  64. ErbB 2item
  65. DNA Methyltransferases 2item
  66. Survivin 1 item
  67. ERK 2item
  68. c-MET 2item
  69. PKC 3item
  70. Ubiquitin-specific proteases 1 item
  71. SGLT 1 item
  72. RAD51 1 item
  73. HER2 1 item
  74. Pyk2 3item
  75. Insulin and Insulin-like Receptors 1 item
  76. PARP 2item
  77. Pyruvate dehydrogenases (PDH) 1 item
  78. ALK 1 item
  79. Dehydrogenase 1 item
  80. PKG 1 item
  81. PKA 4item
  82. AdipoR2 1 item
  83. MK2 1 item
  84. Tie-2 2item
  85. RSK 1 item
  86. Autophagy 1 item
  87. COX 2item
  88. Folate Analogue 1 item
  89. Guanine nucleotide exchange factors (GEFs) 1 item
  90. 20S proteasomal chymotrypsin 1 item
  91. Geranylgeranyltransferase I 1 item
  92. Farnesyltransferase 1 item
  93. Nampt 1 item
  94. eIF4F 1 item
  95. Glutaminases 1 item
  96. MAGL 1 item
  97. P110 1 item
  98. Hck 1 item
  99. Opioid receptors 1 item
  100. FoxM1 1 item
  101. MNK 1 item
  102. eEF-2 1 item
  103. Cdc7 1 item
  104. CMV 1 item
  105. ZAP-70 1 item
  106. Hexokinases 1 item
  107. Flk-1 1 item
  108. Cytidine deaminases 1 item
  109. angiogenesis 1 item
  110. c-RET 1 item
  111. p70 rsk 1 item
  112. Microtubule/Tubulin 1 item
  113. Bfl-1 1 item
  114. p53-MDM2 interaction 1 item
  115. KDR 2item
  116. p53 3item
  117. HDAC 1 item
  118. HDM2 ubiquitin ligase 1 item
  119. DNA Alkylating 1 item
  120. ErbB-2 1 item
  121. PDK-1 1 item
  122. Prk 1 item
  123. HSP70 1 item
  124. Flk1 2item
  125. DHFR 1 item
  126. GARFT 1 item
  127. RHA 1 item
  128. Bcl-w 1 item
  129. SK 1 item
  130. PPK 1 item
  131. c-Syk 1 item
  132. CDK1/CyclinB 1 item
  133. Substance P/NK1 Receptor 1 item
  134. Bax 1 item