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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 1-10 of 153

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  1. ABT-263 (Navitoclax)
    A3007 ABT-263 (Navitoclax)
     15 Citation
    Target: Bcl-2|Bcl-w
    Summary: Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w
      ≥48.73 mg/mL
  2. TW-37
    A4234 TW-37
     1 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1
      insoluble in H2O; ≥19.75 mg/mL
  3. HA14-1
    A8168 HA14-1
    Target: Bcl-2
    Summary: Bcl-2 inhibitor,potent and cell-permeable
      insoluble in H2O; ≥20.45 mg/mL
  4. Apogossypolone (ApoG2)
    A4200 Apogossypolone (ApoG2)
     2 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor,nonpeptidic small molecule
      ≥24.55 mg/mL
  5. PHA-767491
    A3721 PHA-767491
    Target: Cyclin-Dependent Kinases|MK2|Cdc7
    Summary: Cdc7/cdk9 inhibitor, potent, ATP-competitive
      insoluble in H2O; insoluble in EtOH; ≥10.65 mg/mL
  6. RI-2
    B5881 RI-2
    Target: RAD51
    Summary: Optimized reversible RAD51 inhibitor
      ≥21.65 mg/mL
  7. YM155
    A4221 YM155
     2 Citation
    Target: Survivin
    Summary: Survivin suppressant,apoptosis inhibitor
      ≥22.15 mg/mL
  8. PAC-1
    A8177 PAC-1
     1 Citation
    Target: Caspases
    Summary: Procaspase-3 activator
      insoluble in H2O; ≥13.4 mg/mL
  9. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  10. Nutlin-3
    A4228 Nutlin-3
    Target: MDM2
    Summary: MDM2 antagonist,inhibits MDM2-p53 interaction
      ≥58.2 mg/mL

Items 1-10 of 153

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  1. Signaling Pathways 148item
  2. Natural Products 3item
  3. Lab Reagents 1 item
Reversibility
  1. Reversible 12item
  2. Irreversible 7item
Target
  1. Caspases 3item
  2. Cyclin-Dependent Kinases 7item
  3. Proteasome 2item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 8item
  6. Inhibitor of apoptosis proteins (IAP) 2item
  7. Akt 2item
  8. Bcl-2 4item
  9. PI3K 3item
  10. CXCR 1 item
  11. Raf 4item
  12. Aurora Kinases 3item
  13. Bcl-xl 2item
  14. CSF-1R 1 item
  15. MDM2 2item
  16. EZH2 1 item
  17. mTOR 4item
  18. Bromodomains 1 item
  19. AP-1 1 item
  20. MMP 2item
  21. Androgen Receptors 1 item
  22. DT-diaphorases 1 item
  23. FLT3 2item
  24. GSK-3 1 item
  25. P-glycoprotein (P-gp) 1 item
  26. PLK 1 item
  27. Chk 2item
  28. Eph Receptors 2item
  29. VEGFR 17item
  30. PDGFR 7item
  31. c-Kit 3item
  32. RET 2item
  33. Phosphodiesterases (PDEs) 1 item
  34. Mcl-1 2item
  35. JNK 1 item
  36. Bcr-Abl 2item
  37. MEK 7item
  38. DOT1L 1 item
  39. FGFR 4item
  40. Deubiquitinating enzymes (DUBs) 1 item
  41. Smoothened 1 item
  42. MET 4item
  43. Src 3item
  44. RARs 1 item
  45. Trk Receptors 1 item
  46. Aminopeptidases 1 item
  47. STAT 1 item
  48. Microtubules/Tubulins 1 item
  49. Estrogen and Related Receptors 1 item
  50. EGFR 7item
  51. Hedgehog 1 item
  52. PAK 1 item
  53. FAK 3item
  54. BMP and Other Activin Receptors 1 item
  55. JAK 4item
  56. Syk 1 item
  57. EZH1 1 item
  58. DNA-PK 1 item
  59. HSP90 4item
  60. TNKS 1 item
  61. Cytochrome P450 (CYP450) 2item
  62. Ksp 1 item
  63. ErbB 2item
  64. DNA Methyltransferases 2item
  65. Survivin 1 item
  66. ERK 1 item
  67. c-MET 2item
  68. Ubiquitin-specific proteases 1 item
  69. SGLT 1 item
  70. RAD51 1 item
  71. HER2 1 item
  72. Pyk2 3item
  73. Dehydrogenase 1 item
  74. AdipoR2 1 item
  75. MK2 1 item
  76. Tie-2 1 item
  77. COX 2item
  78. Folate Analogue 1 item
  79. Guanine nucleotide exchange factors (GEFs) 1 item
  80. 20S proteasomal chymotrypsin 1 item
  81. Geranylgeranyltransferase I 1 item
  82. Farnesyltransferase 1 item
  83. eIF4F 1 item
  84. MAGL 1 item
  85. P110 1 item
  86. Hck 1 item
  87. Opioid receptors 1 item
  88. FoxM1 1 item
  89. eEF-2 1 item
  90. Cdc7 1 item
  91. CMV 1 item
  92. ZAP-70 1 item
  93. Hexokinases 1 item
  94. Flk-1 1 item
  95. Cytidine deaminases 1 item
  96. angiogenesis 1 item
  97. p53-MDM2 interaction 1 item
  98. Bcl-w 1 item
  99. SK 1 item
  100. Substance P/NK1 Receptor 1 item