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  • Search results for: 'research area apoptosis bcl xl'

Search results for: 'research area apoptosis bcl xl'

Items 11-20 of 234

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  1. Apoptosis Activator 2
    A4016 Apoptosis Activator 2
    Summary: Indoledione caspase activator, cell-permeable
      Soluble in DMSO
  2. prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]
    A1085 prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]
    Summary: Transcriptional repressor
      ≥62.3 mg/mL
  3. ABT-263 (Navitoclax)
    A3007 ABT-263 (Navitoclax)
     15 Citation
    Target: Bcl-2|Bcl-w
    Summary: Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w
      ≥48.73 mg/mL
  4. XL388
    A3940 XL388
    Summary: MTOR inhibitor,highly potent and selective
      insoluble in EtOH; insoluble in H2O; ≥6.87 mg/mL
  5. ABT-199
    A8194 ABT-199
     14 Citation
    Target: Bcl-2
    Summary: Bcl-2 inhibitor,potent and selective
      ≥43.42 mg/mL
  6. AT-101
    A3196 AT-101
    Target: NS3/4a Proteases
    Summary: BH3-mimetic,gossypol enantiomer
      ≥20.7 mg/mL
  7. Obatoclax mesylate (GX15-070)
    A4194 Obatoclax mesylate (GX15-070)
     1 Citation
    Target: Bcl-2
    Summary: Potent Bcl-2 inhibitor
      insoluble in H2O; ≥20.7 mg/mL
  8. 2,3-DCPE hydrochloride
    A4447 2,3-DCPE hydrochloride
    Target: Apoptosis Inducers
    Summary: Bcl-XL protein expression downregulator
      <30.06 mg/mL
  9. Muristerone A
    A4466 Muristerone A
    Summary: TRAIL- and hFasL-induced apoptosis inhibitor
      Soluble in DMSO
  10. Sabutoclax
    A4199 Sabutoclax
     2 Citation
    Target: Bcl-2|Mcl-1|Bfl-1
    Summary: pan-Bcl-2 inhibitor
      insoluble in H2O; ≥205.6 mg/mL

Items 11-20 of 234

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  1. Proteases 24item
  2. Apoptosis 135item
  3. Chromatin/Epigenetics 15item
  4. Metabolism 8item
  5. MAPK Signaling 6item
  6. Tyrosine Kinase 11item
  7. DNA Damage/DNA Repair 9item
  8. PI3K/Akt/mTOR Signaling 3item
  9. Microbiology & Virology 2item
  10. Cell Cycle/Checkpoint 8item
  11. Ubiquitination/ Proteasome 6item
  12. JAK/STAT Signaling 7item
  13. TGF-β / Smad Signaling 2item
  14. Angiogenesis 2item
  15. GPCR/G protein 1 item
  16. Stem Cell 2item
  17. Membrane Transporter/Ion Channel 1 item
  18. Cancer Biology 21item
  19. Endocrinology and Hormones 14item
  20. Neuroscience 11item
  21. Obesity, Appetite Control & Diabetes 4item
  22. Other Signal Transduction 24item
  23. Others 12item
  24. Immunology/Inflammation 10item
  25. Cardiovascular 14item
Specificity
  1. Selective 59item
Reversibility
  1. Reversible 1 item
  2. Irreversible 6item
Target
  1. Caspases 11item
  2. Cyclin-Dependent Kinases 1 item
  3. Proteasome 2item
  4. Histone Deacetylases (HDACs) 4item
  5. Inhibitor of apoptosis proteins (IAP) 2item
  6. Bcl-2 8item
  7. Raf 2item
  8. Aurora Kinases 1 item
  9. Bcl-xl 3item
  10. MDM2 2item
  11. AP-1 1 item
  12. DT-diaphorases 1 item
  13. GSK-3 1 item
  14. VEGFR 3item
  15. PDGFR 3item
  16. c-Kit 2item
  17. RET 1 item
  18. Mcl-1 4item
  19. Thymidylate Synthase 1 item
  20. JNK 1 item
  21. Bcr-Abl 1 item
  22. Nrf2 1 item
  23. Sir2-like Family Deacetylases (Sirtuins) 1 item
  24. Deubiquitinating enzymes (DUBs) 1 item
  25. Smoothened 1 item
  26. Aminopeptidases 1 item
  27. STAT 1 item
  28. RIP kinases 1 item
  29. JAK 4item
  30. HSP90 2item
  31. Topoisomerases 1 item
  32. Survivin 1 item
  33. Ubiquitin-specific proteases 1 item
  34. Melanocortin (MC) Receptors 1 item
  35. Dehydrogenase 1 item
  36. MK2 1 item
  37. Fatty-acid-binding proteins (FABPs) 1 item
  38. Autophagy 1 item
  39. COX 1 item
  40. NADPH Oxidases 1 item
  41. MAGL 1 item
  42. Histamine H1 Receptors 1 item
  43. iNOS 1 item
  44. TRP Channel 1 item
  45. Apoptosis Inducers 1 item
  46. Glucocorticoid Receptors 1 item
  47. Cdc7 1 item
  48. angiogenesis 1 item
  49. c-RET 1 item
  50. FPTase 1 item
  51. Bfl-1 1 item
  52. sodium channels 1 item
  53. p53 4item
  54. cysteine protease 1 item
  55. HDM2 ubiquitin ligase 1 item
  56. PC-PLC 1 item
  57. HIV 1 item
  58. Histone Acetyltransferases (HATs) 1 item
  59. Telomerases 1 item
  60. Tyrosinases 1 item
  61. HSP70 1 item
  62. phosphatidylinositol kinase 1 item
  63. Adenosine Deaminases 1 item
  64. p21 1 item
  65. DHFR 1 item
  66. GARFT 1 item
  67. RHA 1 item
  68. TRPC channel 1 item
  69. PKD 1 item
  70. Bcl-w 1 item
  71. Bax 1 item
  72. NS3/4a Proteases 1 item
Reported Experiments
  1. Animal Experiments 77item
  2. Cell Experiments 64item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Adrenocortical Carcinoma 1 item
  3. Autoimmune Diseases 1 item
  4. Breast Cancer 11item
  5. Cancer 52item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Chronic Myeloproliferative Disorders 1 item
  8. Colon Cancer 5item
  9. Colon Carcinoma 1 item
  10. Colorectal Cancer 3item
  11. Glioblastoma 5item
  12. HCV 1 item
  13. Hepatocellular Carcinoma 1 item
  14. Inflammatory Diseases 2item
  15. Leukemia 2item
  16. Lung Cancer 2item
  17. Lymphoma 4item
  18. Medulloblastoma 1 item
  19. Melanoma 5item
  20. Multiple Myeloma 1 item
  21. Myelofibrosis 1 item
  22. Myeloma 1 item
  23. Neuroblastoma 1 item
  24. Non-small Cell Lung Cancer 3item
  25. Ovarian Cancer 1 item
  26. Pain Relief 1 item
  27. Pancreatic Cancer 3item
  28. Pancreatic Carcinoma 1 item
  29. Pentacyclic Triterpenoid 1 item
  30. Prostate Cancer 8item
  31. Pulmonary Fibrosis 1 item
  32. Rheumatoid Arthritis 2item
  33. Soft Tissue Sarcoma 1 item
  34. Testicular Cancer 1 item
  35. Type 2 Diabetes 2item