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  • Search results for: 'research area apoptosis bcl xl'

Search results for: 'research area apoptosis bcl xl'

Items 1-10 of 49

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  1. XL-888
    A4388 XL-888
     1 Citation
    Target: HSP90
    Summary: Hsp90 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥18.2 mg/mL
  2. TW-37
    A4234 TW-37
     1 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1
      insoluble in H2O; ≥19.75 mg/mL
  3. HA14-1
    A8168 HA14-1
    Target: Bcl-2
    Summary: Bcl-2 inhibitor,potent and cell-permeable
      insoluble in H2O; ≥20.45 mg/mL
  4. PHA-767491
    A3721 PHA-767491
    Target: Cyclin-Dependent Kinases|MK2|Cdc7
    Summary: Cdc7/cdk9 inhibitor, potent, ATP-competitive
      insoluble in H2O; insoluble in EtOH; ≥10.65 mg/mL
  5. ABT-263 (Navitoclax)
    A3007 ABT-263 (Navitoclax)
     15 Citation
    Target: Bcl-2|Bcl-w
    Summary: Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w
      ≥48.73 mg/mL
  6. ABT-199
    A8194 ABT-199
     14 Citation
    Target: Bcl-2
    Summary: Bcl-2 inhibitor,potent and selective
      ≥43.42 mg/mL
  7. Apogossypolone (ApoG2)
    A4200 Apogossypolone (ApoG2)
     2 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor,nonpeptidic small molecule
      ≥24.55 mg/mL
  8. XL019
    A3937 XL019
    Target: JAK
    Summary: JAK2 inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥11.125 mg/mL
  9. YM155
    A4221 YM155
     2 Citation
    Target: Survivin
    Summary: Survivin suppressant,apoptosis inhibitor
      ≥22.15 mg/mL
  10. BMS-833923
    A3258 BMS-833923
    Target: Smoothened
    Summary: Smoothened inhibitor
      ≥47.4 mg/mL

Items 1-10 of 49

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Category
  1. Proteases 8item
  2. Apoptosis 31item
  3. Chromatin/Epigenetics 6item
  4. Metabolism 4item
  5. Tyrosine Kinase 2item
  6. DNA Damage/DNA Repair 4item
  7. PI3K/Akt/mTOR Signaling 1 item
  8. Cell Cycle/Checkpoint 1 item
  9. Ubiquitination/ Proteasome 2item
  10. JAK/STAT Signaling 3item
  11. Angiogenesis 1 item
  12. Stem Cell 2item
  13. Neuroscience 1 item
  14. Obesity, Appetite Control & Diabetes 1 item
  15. Other Signal Transduction 1 item
  16. Others 2item
  17. Immunology/Inflammation 2item
Reversibility
  1. Irreversible 2item
Target
  1. Caspases 5item
  2. Cyclin-Dependent Kinases 1 item
  3. Proteasome 1 item
  4. Histone Deacetylases (HDACs) 3item
  5. Inhibitor of apoptosis proteins (IAP) 2item
  6. Bcl-2 5item
  7. Raf 1 item
  8. Bcl-xl 2item
  9. MDM2 2item
  10. AP-1 1 item
  11. DT-diaphorases 1 item
  12. GSK-3 1 item
  13. VEGFR 2item
  14. PDGFR 2item
  15. c-Kit 1 item
  16. RET 1 item
  17. Mcl-1 2item
  18. Bcr-Abl 1 item
  19. Deubiquitinating enzymes (DUBs) 1 item
  20. Smoothened 1 item
  21. STAT 1 item
  22. RIP kinases 1 item
  23. JAK 3item
  24. HSP90 2item
  25. Survivin 1 item
  26. Ubiquitin-specific proteases 1 item
  27. Melanocortin (MC) Receptors 1 item
  28. Dehydrogenase 1 item
  29. MK2 1 item
  30. Fatty-acid-binding proteins (FABPs) 1 item
  31. NADPH Oxidases 1 item
  32. MAGL 1 item
  33. TRP Channel 1 item
  34. Cdc7 1 item
  35. angiogenesis 1 item
  36. PC-PLC 1 item
  37. PKD 1 item
  38. Bcl-w 1 item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Adrenocortical Carcinoma 1 item
  3. Autoimmune Diseases 1 item
  4. Breast Cancer 11item
  5. Cancer 34item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Chronic Myeloproliferative Disorders 1 item
  8. Colon Cancer 3item
  9. Colon Carcinoma 1 item
  10. Colorectal Cancer 3item
  11. Glioblastoma 5item
  12. Hepatocellular Carcinoma 1 item
  13. Inflammatory Diseases 2item
  14. Leukemia 2item
  15. Lung Cancer 1 item
  16. Lymphoma 3item
  17. Medulloblastoma 1 item
  18. Melanoma 5item
  19. Multiple Myeloma 1 item
  20. Myelofibrosis 1 item
  21. Myeloma 1 item
  22. Neuroblastoma 1 item
  23. Non-small Cell Lung Cancer 3item
  24. Ovarian Cancer 1 item
  25. Pain Relief 1 item
  26. Pancreatic Cancer 3item
  27. Pancreatic Carcinoma 1 item
  28. Prostate Cancer 8item
  29. Pulmonary Fibrosis 1 item
  30. Rheumatoid Arthritis 2item
  31. Soft Tissue Sarcoma 1 item
  32. Testicular Cancer 1 item
  33. Type 2 Diabetes 2item