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  • Search results for: 'research area apoptosis bcl xl'

Search results for: 'research area apoptosis bcl xl'

Items 1-10 of 80

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  1. XL-888
    A4388 XL-888
     1 Citation
    Target: HSP90
    Summary: Hsp90 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥18.2 mg/mL
  2. TW-37
    A4234 TW-37
     1 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1
      insoluble in H2O; ≥19.75 mg/mL
  3. HA14-1
    A8168 HA14-1
    Target: Bcl-2
    Summary: Bcl-2 inhibitor,potent and cell-permeable
      insoluble in H2O; ≥20.45 mg/mL
  4. PHA-767491
    A3721 PHA-767491
    Target: Cyclin-Dependent Kinases|MK2|Cdc7
    Summary: Cdc7/cdk9 inhibitor, potent, ATP-competitive
      insoluble in H2O; insoluble in EtOH; ≥10.65 mg/mL
  5. ABT-263 (Navitoclax)
    A3007 ABT-263 (Navitoclax)
     15 Citation
    Target: Bcl-2|Bcl-w
    Summary: Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w
      ≥48.73 mg/mL
  6. ABT-199
    A8194 ABT-199
     14 Citation
    Target: Bcl-2
    Summary: Bcl-2 inhibitor,potent and selective
      ≥43.42 mg/mL
  7. AT-101
    A3196 AT-101
    Target: NS3/4a Proteases
    Summary: BH3-mimetic,gossypol enantiomer
      ≥20.7 mg/mL
  8. Obatoclax mesylate (GX15-070)
    A4194 Obatoclax mesylate (GX15-070)
     1 Citation
    Target: Bcl-2
    Summary: Potent Bcl-2 inhibitor
      insoluble in H2O; ≥20.7 mg/mL
  9. Sabutoclax
    A4199 Sabutoclax
     2 Citation
    Target: Bcl-2|Mcl-1|Bfl-1
    Summary: pan-Bcl-2 inhibitor
      insoluble in H2O; ≥205.6 mg/mL
  10. Apogossypolone (ApoG2)
    A4200 Apogossypolone (ApoG2)
     2 Citation
    Target: Bcl-2|Bcl-xl|Mcl-1
    Summary: Bcl-2 inhibitor,nonpeptidic small molecule
      ≥24.55 mg/mL

Items 1-10 of 80

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  1. Signaling Pathways 77item
  2. Natural Products 4item
  3. Lab Reagents 1 item
Specificity
  1. Selective 49item
Reversibility
  1. Irreversible 4item
Target
  1. Caspases 6item
  2. Cyclin-Dependent Kinases 1 item
  3. Proteasome 1 item
  4. Histone Deacetylases (HDACs) 4item
  5. Inhibitor of apoptosis proteins (IAP) 2item
  6. Bcl-2 8item
  7. Raf 2item
  8. Aurora Kinases 1 item
  9. Bcl-xl 2item
  10. MDM2 2item
  11. AP-1 1 item
  12. DT-diaphorases 1 item
  13. GSK-3 1 item
  14. VEGFR 3item
  15. PDGFR 3item
  16. c-Kit 2item
  17. RET 1 item
  18. Mcl-1 3item
  19. Thymidylate Synthase 1 item
  20. Bcr-Abl 1 item
  21. Nrf2 1 item
  22. Sir2-like Family Deacetylases (Sirtuins) 1 item
  23. Deubiquitinating enzymes (DUBs) 1 item
  24. Smoothened 1 item
  25. Aminopeptidases 1 item
  26. STAT 1 item
  27. Estrogen and Related Receptors 1 item
  28. RIP kinases 1 item
  29. Hypoxia Inducible Factors (HIFs) 1 item
  30. JAK 4item
  31. HSP90 2item
  32. Topoisomerases 1 item
  33. Cytochrome P450 (CYP450) 1 item
  34. Survivin 1 item
  35. Ubiquitin-specific proteases 1 item
  36. Melanocortin (MC) Receptors 1 item
  37. Dehydrogenase 1 item
  38. MK2 1 item
  39. Fatty-acid-binding proteins (FABPs) 1 item
  40. Autophagy 1 item
  41. NADPH Oxidases 1 item
  42. MAGL 1 item
  43. Histamine H1 Receptors 1 item
  44. TRP Channel 1 item
  45. Glucocorticoid Receptors 1 item
  46. Cdc7 1 item
  47. angiogenesis 1 item
  48. c-RET 1 item
  49. FPTase 1 item
  50. Bfl-1 1 item
  51. p53 4item
  52. cysteine protease 1 item
  53. HDM2 ubiquitin ligase 1 item
  54. PC-PLC 1 item
  55. Glucosidases 1 item
  56. HIV 1 item
  57. Histone Acetyltransferases (HATs) 1 item
  58. Telomerases 1 item
  59. Tyrosinases 1 item
  60. HSP70 1 item
  61. phosphatidylinositol kinase 1 item
  62. Adenosine Deaminases 1 item
  63. p21 1 item
  64. DHFR 1 item
  65. GARFT 1 item
  66. RHA 1 item
  67. TRPC channel 1 item
  68. PKD 1 item
  69. Bcl-w 1 item
  70. Bax 1 item
  71. NS3/4a Proteases 1 item
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