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  • Search results for: 'research area apoptosis p53'

Search results for: 'research area apoptosis p53'

Items 11-20 of 243

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  1. Nutlin-3
    A4228 Nutlin-3
    Target: MDM2
    Summary: MDM2 antagonist,inhibits MDM2-p53 interaction
      ≥58.2 mg/mL
  2. CP 31398 dihydrochloride
    A4476 CP 31398 dihydrochloride
    Summary: p53 stabilizer
      <43.54 mg/mL
  3. PRIMA-1MET
    A4484 PRIMA-1MET
    Summary: Restore mutant p53 activity, induce BAX and PUMA
  4. PRIMA-1
    A4483 PRIMA-1
    Target: p53
    Summary: BAX inhibitor
      ≥110.6 mg/mL
  5. Cyclic Pifithrin-α hydrobromide
    A4477 Cyclic Pifithrin-α hydrobromide
    Summary: P53 inhibitor
      insoluble in H2O; ≥25 mg/mL
  6. Tenovin-1
    A4203 Tenovin-1
    Target: Sir2-like Family Deacetylases (Sirtuins)|p53|p21
    Summary: SIRT2 inhibitor, activates p53
      insoluble in H2O; insoluble in EtOH; ≥15 mg/mL
  7. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  8. Plumbagin
    A4456 Plumbagin
    Summary: Anticancer agent
  9. SJ 172550
    A4486 SJ 172550
    Summary: MDMX inhibitor
      ≥27.55 mg/mL
  10. HLI 373
    A4478 HLI 373
    Summary: Hdm2 ubiquitin ligase (E3) inhibitor
      <37.79 mg/mL

Items 11-20 of 243

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Category
  1. Proteases 23item
  2. Apoptosis 146item
  3. Chromatin/Epigenetics 17item
  4. Metabolism 7item
  5. MAPK Signaling 3item
  6. Tyrosine Kinase 10item
  7. DNA Damage/DNA Repair 9item
  8. PI3K/Akt/mTOR Signaling 3item
  9. Microbiology & Virology 2item
  10. Cell Cycle/Checkpoint 8item
  11. Ubiquitination/ Proteasome 7item
  12. JAK/STAT Signaling 6item
  13. TGF-β / Smad Signaling 2item
  14. Angiogenesis 2item
  15. GPCR/G protein 1 item
  16. Stem Cell 1 item
  17. Membrane Transporter/Ion Channel 1 item
  18. Cancer Biology 21item
  19. Endocrinology and Hormones 14item
  20. Neuroscience 11item
  21. Obesity, Appetite Control & Diabetes 4item
  22. Other Signal Transduction 24item
  23. Others 12item
  24. Immunology/Inflammation 10item
  25. Cardiovascular 14item
Specificity
  1. Selective 58item
Reversibility
  1. Reversible 2item
  2. Irreversible 6item
Target
  1. Caspases 11item
  2. Cyclin-Dependent Kinases 2item
  3. Proteasome 3item
  4. Histone Deacetylases (HDACs) 4item
  5. Inhibitor of apoptosis proteins (IAP) 2item
  6. Bcl-2 5item
  7. Raf 2item
  8. Aurora Kinases 1 item
  9. Bcl-xl 2item
  10. MDM2 2item
  11. AP-1 1 item
  12. DT-diaphorases 1 item
  13. GSK-3 1 item
  14. VEGFR 3item
  15. PDGFR 2item
  16. c-Kit 2item
  17. RET 1 item
  18. Mcl-1 2item
  19. Thymidylate Synthase 1 item
  20. JNK 1 item
  21. Nrf2 1 item
  22. Sir2-like Family Deacetylases (Sirtuins) 2item
  23. Deubiquitinating enzymes (DUBs) 1 item
  24. Aminopeptidases 1 item
  25. STAT 1 item
  26. RIP kinases 1 item
  27. JAK 3item
  28. HSP90 1 item
  29. Topoisomerases 1 item
  30. Survivin 1 item
  31. Ubiquitin-specific proteases 1 item
  32. SMYD2 1 item
  33. Melanocortin (MC) Receptors 1 item
  34. MK2 1 item
  35. Fatty-acid-binding proteins (FABPs) 1 item
  36. Autophagy 1 item
  37. COX 1 item
  38. NADPH Oxidases 1 item
  39. MAGL 1 item
  40. Histamine H1 Receptors 1 item
  41. iNOS 1 item
  42. TRP Channel 1 item
  43. Apoptosis Inducers 1 item
  44. Glucocorticoid Receptors 1 item
  45. Cdc7 1 item
  46. angiogenesis 1 item
  47. c-RET 1 item
  48. FPTase 1 item
  49. sodium channels 1 item
  50. p53-MDM2 interaction 2item
  51. p53 7item
  52. cysteine protease 1 item
  53. HDM2 ubiquitin ligase 1 item
  54. PC-PLC 1 item
  55. HIV 1 item
  56. Histone Acetyltransferases (HATs) 1 item
  57. Telomerases 1 item
  58. Tyrosinases 1 item
  59. HSP70 1 item
  60. phosphatidylinositol kinase 1 item
  61. MDMX 1 item
  62. Adenosine Deaminases 1 item
  63. p21 1 item
  64. DHFR 1 item
  65. GARFT 1 item
  66. RHA 1 item
  67. TRPC channel 1 item
  68. PKD 1 item
  69. Bcl-w 1 item
  70. Sirtuin 1 item
  71. Bax 1 item
  72. NS3/4a Proteases 1 item
Reported Experiments
  1. Animal Experiments 76item
  2. Cell Experiments 68item
Related Disease
  1. Autoimmune Diseases 1 item
  2. Breast Cancer 10item
  3. Cancer 48item
  4. Chronic Lymphocytic Leukemia 1 item
  5. Chronic Myeloproliferative Disorders 1 item
  6. Colon Cancer 5item
  7. Colon Carcinoma 1 item
  8. Colorectal Cancer 3item
  9. Glioblastoma 4item
  10. HCV 1 item
  11. Hepatocellular Carcinoma 1 item
  12. Inflammatory Diseases 2item
  13. Leukemia 1 item
  14. Lung Cancer 2item
  15. Lymphoma 4item
  16. Melanoma 4item
  17. Multiple Myeloma 1 item
  18. Myelofibrosis 1 item
  19. Myeloma 1 item
  20. Neuroblastoma 1 item
  21. Non-small Cell Lung Cancer 2item
  22. Ovarian Cancer 1 item
  23. Pain Relief 1 item
  24. Pancreatic Cancer 3item
  25. Pentacyclic Triterpenoid 1 item
  26. Prostate Cancer 7item
  27. Pulmonary Fibrosis 1 item
  28. Rheumatoid Arthritis 2item
  29. Soft Tissue Sarcoma 1 item
  30. Testicular Cancer 1 item
  31. Type 2 Diabetes 2item