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  • Search results for: 'research area apoptosis p53'

Search results for: 'research area apoptosis p53'

Items 111-120 of 146

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  1. WEHI-539
    A3935 WEHI-539
     15 Citation
    Target: Bcl-xl
    Summary: Bcl-xL inhibitor,potent and selective
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  2. ABT-737
    A8193 ABT-737
     14 Citation
    Summary: Bcl-2 inhibitor
      ≥40.67 mg/mL
  3. Regorafenib hydrochloride
    A3750 Regorafenib hydrochloride
    Target: Raf|VEGFR|PDGFR|c-Kit|c-RET
    Summary: Tyrosine kinase inhibitor
      ≥25.95 mg/mL
  4. Regorafenib monohydrate
    A3751 Regorafenib monohydrate
    Summary: Tyrosine kinase inhibitor
      ≥25.05 mg/mL
  5. Danusertib (PHA-739358)
    A4116 Danusertib (PHA-739358)
     2 Citation
    Target: Aurora Kinases
    Summary: Pan-aurora kinase inhibitor
      ≥23.75 mg/mL
  6. Caspase-3/7 Inhibitor I
    A1925 Caspase-3/7 Inhibitor I
     2 Citation
    Target: Caspases
    Summary: Caspase-3/7 inhibitor
      insoluble in H2O; ≥16.2 mg/mL
  7. Regorafenib
    A8236 Regorafenib
     4 Citation
    Target: Raf|VEGFR|PDGFR|c-Kit|RET
    Summary: Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1
      ≥25.04 mg/mL
  8. CID 2011756
    A8223 CID 2011756
    Summary: PKD inhibitor
      ≥39.7 mg/mL
  9. TG101209
    A4145 TG101209
    Summary: JAK2/3 inhibitor
      ≥25.5 mg/mL
  10. Amuvatinib (MP-470, HPK 56)
    A4237 Amuvatinib (MP-470, HPK 56)
    Summary: Tyrosine kinase inhibitor
      ≥22.4 mg/mL

Items 111-120 of 146

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Category
  1. Caspase 21item
  2. 14.3.3 Proteins 1 item
  3. Apoptosis Inducers 36item
  4. Bax 6item
  5. Bcl-2 Family 17item
  6. Bcl-xL 6item
  7. c-RET 7item
  8. IAP 5item
  9. KEAP1-Nrf2 2item
  10. MDM2 10item
  11. p53 36item
  12. PC-PLC 1 item
  13. PKD 4item
  14. RasGAP (Ras- P21) 1 item
  15. Survivin 2item
  16. Thymidylate Synthase 2item
  17. TNF-α 5item
  18. Other Apoptosis 6item
  19. ASK1 2item
  20. PAR4 1 item
Specificity
  1. Selective 38item
Reversibility
  1. Reversible 1 item
  2. Irreversible 6item
Target
  1. Caspases 11item
  2. Proteasome 1 item
  3. Histone Deacetylases (HDACs) 2item
  4. Inhibitor of apoptosis proteins (IAP) 2item
  5. Bcl-2 5item
  6. Raf 2item
  7. Aurora Kinases 1 item
  8. Bcl-xl 2item
  9. MDM2 2item
  10. VEGFR 3item
  11. PDGFR 2item
  12. c-Kit 2item
  13. RET 1 item
  14. Mcl-1 2item
  15. Thymidylate Synthase 1 item
  16. Nrf2 1 item
  17. Sir2-like Family Deacetylases (Sirtuins) 1 item
  18. Deubiquitinating enzymes (DUBs) 1 item
  19. Aminopeptidases 1 item
  20. RIP kinases 1 item
  21. Topoisomerases 1 item
  22. Survivin 1 item
  23. Autophagy 1 item
  24. COX 1 item
  25. iNOS 1 item
  26. TRP Channel 1 item
  27. Apoptosis Inducers 1 item
  28. angiogenesis 1 item
  29. c-RET 1 item
  30. FPTase 1 item
  31. p53-MDM2 interaction 2item
  32. p53 7item
  33. cysteine protease 1 item
  34. HDM2 ubiquitin ligase 1 item
  35. PC-PLC 1 item
  36. HIV 1 item
  37. Histone Acetyltransferases (HATs) 1 item
  38. Telomerases 1 item
  39. Tyrosinases 1 item
  40. HSP70 1 item
  41. MDMX 1 item
  42. p21 1 item
  43. DHFR 1 item
  44. GARFT 1 item
  45. PKD 1 item
  46. Bcl-w 1 item
  47. Bax 1 item
  48. NS3/4a Proteases 1 item
Reported Experiments
  1. Animal Experiments 50item
  2. Cell Experiments 43item
Related Disease
  1. Autoimmune Diseases 1 item
  2. Breast Cancer 6item
  3. Cancer 34item
  4. Chronic Lymphocytic Leukemia 1 item
  5. Chronic Myeloproliferative Disorders 1 item
  6. Colon Cancer 4item
  7. Colorectal Cancer 2item
  8. Glioblastoma 3item
  9. HCV 1 item
  10. Hepatocellular Carcinoma 1 item
  11. Inflammatory Diseases 1 item
  12. Lung Cancer 2item
  13. Lymphoma 4item
  14. Melanoma 2item
  15. Multiple Myeloma 1 item
  16. Myelofibrosis 1 item
  17. Neuroblastoma 1 item
  18. Non-small Cell Lung Cancer 1 item
  19. Ovarian Cancer 1 item
  20. Pain Relief 1 item
  21. Pancreatic Cancer 2item
  22. Pentacyclic Triterpenoid 1 item
  23. Prostate Cancer 4item
  24. Pulmonary Fibrosis 1 item
  25. Rheumatoid Arthritis 1 item
  26. Soft Tissue Sarcoma 1 item
  27. Testicular Cancer 1 item