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  • Search results for: 'research area cell cycle atm atr'

Search results for: 'research area cell cycle atm atr'

Items 41-50 of 565

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  1. LY2835219
    A1794 LY2835219
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,potent and selective
      ≥30.15 mg/mL
  2. PD 0332991 (Palbociclib) HCl
    A8316 PD 0332991 (Palbociclib) HCl
     5 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥14.48 mg/mL
  3. Palbociclib (PD0332991) Isethionate
    A8335 Palbociclib (PD0332991) Isethionate
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥28.7 mg/mL
  4. PHA-848125
    A8501 PHA-848125
    Target: Cyclin-Dependent Kinases
    Summary: CDK inhibitor,potent and ATP-competitive
      ≥23.05 mg/mL
  5. BMS265246
    A8385 BMS265246
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/2 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL
  6. Dinaciclib (SCH727965)
    A8412 Dinaciclib (SCH727965)
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK inhibitor
  7. Deferasirox
    A8639 Deferasirox
    Summary: Oral iron chelator
      insoluble in H2O; ≥37.28 mg/mL
  8. Flavopiridol hydrochloride
    A8640 Flavopiridol hydrochloride
    Summary: CDK inhibitor, potent and selective
      ≥21.9 mg/mL
  9. LEE011
    A8641 LEE011
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥10.88 mg/mL
  10. WHI-P180
    A8643 WHI-P180
    Summary: EGFR/Janus Kinase 3 inhibitor
      Soluble in DMSO

Items 41-50 of 565

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Category
  1. Proteases 34item
  2. Apoptosis 63item
  3. Chromatin/Epigenetics 75item
  4. Metabolism 24item
  5. MAPK Signaling 18item
  6. Tyrosine Kinase 41item
  7. DNA Damage/DNA Repair 53item
  8. PI3K/Akt/mTOR Signaling 32item
  9. Microbiology & Virology 14item
  10. Cell Cycle/Checkpoint 85item
  11. Ubiquitination/ Proteasome 19item
  12. JAK/STAT Signaling 25item
  13. TGF-β / Smad Signaling 23item
  14. Angiogenesis 6item
  15. GPCR/G protein 21item
  16. Stem Cell 45item
  17. Membrane Transporter/Ion Channel 19item
  18. Cancer Biology 18item
  19. Endocrinology and Hormones 7item
  20. Neuroscience 16item
  21. Obesity, Appetite Control & Diabetes 2item
  22. Other Signal Transduction 12item
  23. Others 50item
  24. Immunology/Inflammation 18item
  25. Cardiovascular 5item
  26. Vitamin D Related 3item
  27. NF-κB 1 item
Specificity
  1. Selective 178item
Reversibility
  1. Reversible 22item
  2. Irreversible 9item
Target
  1. Caspases 8item
  2. Cyclin-Dependent Kinases 17item
  3. Proteasome 7item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 15item
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 1 item
  8. Bcl-2 2item
  9. PI3K 6item
  10. Raf 2item
  11. Aurora Kinases 6item
  12. Bcl-xl 1 item
  13. Glycoproteins 1 item
  14. MDM2 1 item
  15. EZH2 3item
  16. mTOR 4item
  17. Bromodomains 1 item
  18. AP-1 2item
  19. MMP 1 item
  20. Myosin II ATPases 1 item
  21. FLT3 2item
  22. GSK-3 4item
  23. LPA Receptors 1 item
  24. P-glycoprotein (P-gp) 3item
  25. PLK 7item
  26. Chk 4item
  27. VEGFR 4item
  28. PDGFR 3item
  29. c-Kit 1 item
  30. Bromodomain-containing proteins(BRDs) 1 item
  31. Phosphodiesterases (PDEs) 2item
  32. Hydrolase 1 item
  33. p38 1 item
  34. Bcr-Abl 1 item
  35. MEK 2item
  36. PORCN 1 item
  37. DOT1L 1 item
  38. FGFR 2item
  39. Glucagon-like peptide 1 (GLP-1) receptors 1 item
  40. Sir2-like Family Deacetylases (Sirtuins) 1 item
  41. Deubiquitinating enzymes (DUBs) 1 item
  42. Smoothened 2item
  43. Eukaryotic elongation factors 1 item
  44. Src 2item
  45. Trk Receptors 1 item
  46. STAT 3item
  47. Microtubules/Tubulins 4item
  48. Estrogen and Related Receptors 1 item
  49. EGFR 7item
  50. Hedgehog 1 item
  51. Reverse Transcriptases 1 item
  52. ROCK 7item
  53. JAK 5item
  54. p300 1 item
  55. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  56. Syk 1 item
  57. DNA-PK 4item
  58. HSP90 1 item
  59. AMPK 2item
  60. CFTR 3item
  61. TNKS 1 item
  62. ErbB 2item
  63. Toll-like receptors (TLRs) 2item
  64. DNA Methyltransferases 1 item
  65. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  66. ERK 1 item
  67. BMI-1 1 item
  68. PKC 5item
  69. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  70. Lyn 1 item
  71. SGLT 1 item
  72. RAD51 1 item
  73. USP 1 item
  74. LRRK2 2item
  75. Voltage-gated Calcium Channels (CaV) 1 item
  76. ALK 1 item
  77. Sphingosine kinases (SphKs) 1 item
  78. GTPases 1 item
  79. PKA 3item
  80. Fatty-acid-binding proteins (FABPs) 1 item
  81. Tie-2 1 item
  82. Free Fatty Acid Receptors 1 item
  83. phosphatases 1 item
  84. Autophagy 2item
  85. ATM/ATR 8item
  86. CK1 1 item
  87. Farnesyl Diphosphate Synthases 1 item
  88. Melatonin Receptors 1 item
  89. MAGL 1 item
  90. NPY Receptors 1 item
  91. c-Fyn 1 item
  92. Histamine H1 Receptors 2item
  93. RAR/RXR 1 item
  94. TRP Channel 1 item
  95. DYRK 1 item
  96. Apoptosis Inducers 1 item
  97. MNK 1 item
  98. NO Donors / Precursors 1 item
  99. Glucocorticoid Receptors 1 item
  100. IL Receptors 1 item
  101. 15-lipoxygenases 1 item
  102. Inward Rectifier Potassium (Kir) Channels 1 item
  103. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  104. NMDA receptor 1 item
  105. Aldosterone receptor 1 item
  106. DPP-4 1 item
  107. DREADD Ligands 1 item
  108. p70 rsk 1 item
  109. Microtubule/Tubulin 1 item
  110. p53-MDM2 interaction 1 item
  111. KDR 1 item
  112. p53 3item
  113. c-Fms tyrosine kinase 1 item
  114. insulin 1 item
  115. Ub-conjugating enzyme (E2) complex 1 item
  116. Smoothened receptor 1 item
  117. PPAR 1 item
  118. HDM2 ubiquitin ligase 1 item
  119. Vitamin D receptors (VDRs) 1 item
  120. Antibiotic 1 item
  121. DNA Alkylating 1 item
  122. GLI 1 item
  123. Stem Cell Differentiation 1 item
  124. PP2A/Nkd interaction 1 item
  125. adrenergic receptor 1 item
  126. Ribonucleotide Reductases 1 item
  127. Aryl hydrocarbon receptors (AHRs) 1 item
  128. DCLK2 1 item
  129. phosphatidylinositol kinase 1 item
  130. Lck 1 item
  131. Adenosine Deaminases 1 item
  132. Histamine receptors 1 item
  133. GluR 1 item
  134. 5-HT receptor 1 item
  135. dopamine receptors 1 item
  136. AMPA receptor 1 item
  137. Flk1 1 item
  138. p21 1 item
  139. RHA 1 item
  140. TRPC channel 1 item
  141. FKBP 1 item
  142. Bcl-w 1 item
  143. PPK 1 item
  144. c-Syk 1 item
  145. CDK1/CyclinB 1 item
  146. FXR 1 item
  147. Vascular Disrupting Agents (VDA) 1 item
  148. ATM 2item
  149. Sirtuin 1 item
  150. PIKfyve 1 item
  151. Bax 1 item
  152. NS3/4a Proteases 1 item
  153. p90 S6K 1 item
Reported Experiments
  1. Animal Experiments 221item
  2. Cell Experiments 173item
Related Disease
  1. Acne 1 item
  2. Acute Myelogenous Leukemia 1 item
  3. Acute Myeloid Leukemia 7item
  4. Autoimmune Diseases 1 item
  5. Bladder Cancer 4item
  6. B-lymphoid Malignancies 1 item
  7. Breast Cancer 38item
  8. Cancer 139item
  9. Cervical Cancer 1 item
  10. Cholangiocarcinoma 1 item
  11. Chronic Lymphocytic Leukemia 2item
  12. Colon Cancer 15item
  13. Colon Carcinoma 1 item
  14. Colorectal Cancer 15item
  15. Diabetes 3item
  16. Fungal Infection 1 item
  17. Glioblastoma 8item
  18. Glioma 2item
  19. HCV 1 item
  20. Hepatocellular Carcinoma 3item
  21. HIV 1 item
  22. Immunosuppressive Therapy 1 item
  23. Inflammatory Diseases 3item
  24. Leukemia 6item
  25. Liver Cancer 2item
  26. Lung Cancer 8item
  27. Lymphoma 4item
  28. Mantle Cell Lymphoma 2item
  29. Medulloblastoma 1 item
  30. Melanoma 11item
  31. Mixed Lineage Leukemia 1 item
  32. Multiple Myeloma 6item
  33. Neuroblastoma 2item
  34. Non-small Cell Lung Cancer 6item
  35. Non-small Cell Lung Carcinoma 1 item
  36. Ovarian Cancer 11item
  37. Pain Relief 1 item
  38. Pancreatic Cancer 11item
  39. Pancreatic Carcinoma 2item
  40. Prostate Cancer 15item
  41. Psoriasis 2item
  42. Pulmonary Fibrosis 1 item
  43. Renal Cell Carcinoma 2item
  44. Rheumatoid Arthritis 2item
  45. Sleep Disorders 1 item
  46. Type 2 Diabetes 3item