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  • Search results for: 'research area cell cycle e1 enzyme'

Search results for: 'research area cell cycle e1 enzyme'

Items 1-10 of 206

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  1. AZD7762
    A5919 AZD7762
    Target: Chk
    Summary: Checkpoint kinase inhibitor,ATP competitive
      insoluble in H2O; insoluble in EtOH; ≥18.1 mg/mL
  2. MK-8776 (SCH-900776)
    A8477 MK-8776 (SCH-900776)
    Target: Chk
    Summary: Chk1 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥18.8 mg/mL
  3. R547
    A8642 R547
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/2/4 inhibitor,ATP-competitive
      Soluble in DMSO
  4. BS-181 HCl
    A5700 BS-181 HCl
    Target: Cyclin-Dependent Kinases
    Summary: CDK7 inhibitor,highly selective
      insoluble in H2O; ≥20.85 mg/mL
  5. GSK429286A
    A5611 GSK429286A
    Target: ROCK
    Summary: Selective ROCK1/ROCK2 inhibitor
      ≥21.6 mg/mL
  6. Fasudil (HA-1077) HCl
    A5734 Fasudil (HA-1077) HCl
     1 Citation
    Target: ROCK
    Summary: Protein kinase inhibitor
      ≥16.4 mg/mL
  7. CHIR-124
    A8394 CHIR-124
    Target: FLT3|GSK-3|Chk|PDGFR
    Summary: Chk1 inhibitor,novel and potent
      insoluble in H2O; ≥10.5 mg/mL
  8. Ro3280
    A8681 Ro3280
    Target: PLK
    Summary: PLK1 inhibitor,potent and highly selective
      ≥27.2 mg/mL
  9. SLx-2119
    A3825 SLx-2119
     1 Citation
    Target: ROCK
    Summary: Selective ROCK2 inhibitor
      ≥22.65 mg/mL
  10. Y-27632 dihydrochloride
    A3008 Y-27632 dihydrochloride
     19 Citation
    Target: ROCK
    Summary: ROCK1 inhibitor
      ≥111.2 mg/mL

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  1. Signaling Pathways 193item
  2. Natural Products 1 item
  3. Kits 2item
  4. Peptides 1 item
  5. Cell Biology 1 item
  6. Peptides & Proteins 1 item
  7. Lab Reagents 3item
Reversibility
  1. Reversible 20item
  2. Irreversible 8item
Target
  1. Caspases 7item
  2. Cyclin-Dependent Kinases 13item
  3. Proteasome 5item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 12item
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 1 item
  8. Bcl-2 2item
  9. PI3K 4item
  10. Raf 1 item
  11. Aurora Kinases 4item
  12. Bcl-xl 1 item
  13. Glycoproteins 1 item
  14. MDM2 1 item
  15. EZH2 3item
  16. mTOR 1 item
  17. AP-1 2item
  18. MMP 2item
  19. Myosin II ATPases 1 item
  20. FLT3 1 item
  21. GSK-3 4item
  22. LPA Receptors 1 item
  23. P-glycoprotein (P-gp) 3item
  24. PLK 3item
  25. Chk 4item
  26. VEGFR 1 item
  27. PDGFR 2item
  28. c-Kit 1 item
  29. Bromodomain-containing proteins(BRDs) 1 item
  30. Phosphodiesterases (PDEs) 1 item
  31. Hydrolase 1 item
  32. p38 1 item
  33. Bcr-Abl 1 item
  34. MEK 3item
  35. PORCN 1 item
  36. DOT1L 1 item
  37. Glucagon-like peptide 1 (GLP-1) receptors 1 item
  38. Deubiquitinating enzymes (DUBs) 2item
  39. Smoothened 2item
  40. Eukaryotic elongation factors 1 item
  41. Ras 1 item
  42. Src 2item
  43. Trk Receptors 2item
  44. STAT 3item
  45. Microtubules/Tubulins 4item
  46. EGFR 4item
  47. Hedgehog 1 item
  48. Reverse Transcriptases 1 item
  49. ROCK 5item
  50. JAK 2item
  51. p300 1 item
  52. Syk 1 item
  53. DNA-PK 1 item
  54. HSP90 1 item
  55. AMPK 2item
  56. CFTR 3item
  57. TNKS 1 item
  58. Cytochrome P450 (CYP450) 1 item
  59. ErbB 2item
  60. Toll-like receptors (TLRs) 1 item
  61. DNA Methyltransferases 1 item
  62. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  63. ERK 1 item
  64. HMG-CoA Reductases 1 item
  65. BMI-1 1 item
  66. PKC 1 item
  67. Calpains 1 item
  68. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  69. Lyn 1 item
  70. SGLT 1 item
  71. USP 1 item
  72. LRRK2 1 item
  73. Pyruvate dehydrogenases (PDH) 1 item
  74. Sphingosine kinases (SphKs) 1 item
  75. GTPases 1 item
  76. Fatty-acid-binding proteins (FABPs) 1 item
  77. Angiotensin-Converting Enzymes (ACEs) 4item
  78. Tie-2 1 item
  79. Granzyme B 1 item
  80. Free Fatty Acid Receptors 1 item
  81. phosphatases 1 item
  82. Autophagy 2item
  83. ATM/ATR 3item
  84. CK1 1 item
  85. Farnesyl Diphosphate Synthases 1 item
  86. CK2 1 item
  87. Melatonin Receptors 1 item
  88. Peroxynitrite 1 item
  89. MAGL 1 item
  90. NPY Receptors 1 item
  91. c-Fyn 1 item
  92. Histamine H1 Receptors 2item
  93. TRP Channel 1 item
  94. Apoptosis Inducers 1 item
  95. NO Donors / Precursors 1 item
  96. IL Receptors 2item
  97. CCL2 1 item
  98. 15-lipoxygenases 1 item
  99. AChE 1 item
  100. Peptidoglycan synthesis 1 item
  101. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  102. Aldosterone receptor 1 item
  103. NAE 2item
  104. Ubiquitin-activating Enzyme E1 1 item
  105. SUMOylation 1 item
  106. BACE 1 item
  107. 15-PGDH 1 item
  108. DPP-4 1 item
  109. DREADD Ligands 1 item
  110. p53-MDM2 interaction 1 item
  111. c-Fms tyrosine kinase 1 item
  112. Ub-conjugating enzyme (E2) complex 1 item
  113. HCV polymerase 1 item
  114. DCLK2 1 item
  115. Lck 1 item
  116. Bcl-w 1 item
  117. FXR 1 item
  118. ATM 1 item
  119. Sirtuin 1 item
  120. PIKfyve 1 item
Reported Experiments
  1. Animal Experiments 177item
  2. Cell Experiments 116item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 8item
  3. Autoimmune Diseases 1 item
  4. Bladder Cancer 4item
  5. B-lymphoid Malignancies 1 item
  6. Breast Cancer 36item
  7. Cancer 111item
  8. Cholangiocarcinoma 1 item
  9. Chronic Lymphocytic Leukemia 2item
  10. Colon Cancer 17item
  11. Colon Carcinoma 1 item
  12. Colorectal Cancer 16item
  13. Diabetes 2item
  14. Fungal Infection 1 item
  15. Glioblastoma 7item
  16. Glioma 3item
  17. Hepatitis C 1 item
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  22. Leukemia 10item
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  27. Medulloblastoma 1 item
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  29. Mixed Lineage Leukemia 1 item
  30. Multiple Myeloma 8item
  31. Myeloma 1 item
  32. Neuroblastoma 2item
  33. Non-small Cell Lung Cancer 6item
  34. Non-small Cell Lung Carcinoma 1 item
  35. Ovarian Cancer 10item
  36. Pain Relief 1 item
  37. Pancreatic Cancer 12item
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  39. Prostate Cancer 16item
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