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Search results for: 'research area cell cycle plk'

Items 11-20 of 216

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  1. Vincristine sulfate
    A1765 Vincristine sulfate
    Target: Microtubule/Tubulin
    Summary: Microtubule disrupter,antitumor agent
      ≥46.15 mg/mL
  2. GSK429286A
    A5611 GSK429286A
    Target: ROCK
    Summary: Selective ROCK1/ROCK2 inhibitor
      ≥21.6 mg/mL
  3. Fasudil (HA-1077) HCl
    A5734 Fasudil (HA-1077) HCl
     1 Citation
    Target: ROCK
    Summary: Protein kinase inhibitor
      ≥16.4 mg/mL
  4. CHIR-124
    A8394 CHIR-124
    Target: FLT3|GSK-3|Chk|PDGFR
    Summary: Chk1 inhibitor,novel and potent
      insoluble in H2O; ≥10.5 mg/mL
  5. RKI-1447
    A3771 RKI-1447
    Target: ROCK
    Summary: Potent ROCK1/ROCK2 inhibitor
      insoluble in H2O; ≥16.3 mg/mL
  6. SLx-2119
    A3825 SLx-2119
     1 Citation
    Target: ROCK
    Summary: Selective ROCK2 inhibitor
      ≥22.65 mg/mL
  7. Y-27632 dihydrochloride
    A3008 Y-27632 dihydrochloride
     19 Citation
    Target: ROCK
    Summary: ROCK1 inhibitor
      ≥111.2 mg/mL
  8. AZD-5438
    A8326 AZD-5438
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK1/2/9 inhibitor
      insoluble in H2O; ≥18.55 mg/mL
  9. AT7519 Hydrochloride
    A3197 AT7519 Hydrochloride
    Target: Cyclin-Dependent Kinases
    Summary: Multi-CDK inhibitor
      ≥29.93 mg/mL
  10. KU-60019
    A8336 KU-60019
     2 Citation
    Target: ATM/ATR
    Summary: ATM kinase inhibitor,potent and selective
      ≥27.4 mg/mL

Items 11-20 of 216

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Category
  1. Proteases 13item
  2. Apoptosis 20item
  3. Chromatin/Epigenetics 31item
  4. Metabolism 9item
  5. MAPK Signaling 6item
  6. Tyrosine Kinase 19item
  7. DNA Damage/DNA Repair 29item
  8. PI3K/Akt/mTOR Signaling 14item
  9. Microbiology & Virology 4item
  10. Cell Cycle/Checkpoint 39item
  11. Ubiquitination/ Proteasome 10item
  12. JAK/STAT Signaling 13item
  13. TGF-β / Smad Signaling 11item
  14. Angiogenesis 2item
  15. GPCR/G protein 8item
  16. Stem Cell 17item
  17. Membrane Transporter/Ion Channel 8item
  18. Endocrinology and Hormones 3item
  19. Neuroscience 6item
  20. Obesity, Appetite Control & Diabetes 1 item
  21. Others 11item
  22. Immunology/Inflammation 5item
  23. Vitamin D Related 1 item
  24. NF-κB 1 item
Specificity
  1. Selective 151item
Reversibility
  1. Reversible 18item
  2. Irreversible 8item
Target
  1. Caspases 5item
  2. Cyclin-Dependent Kinases 14item
  3. Proteasome 5item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 13item
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 1 item
  8. Bcl-2 2item
  9. PI3K 3item
  10. Raf 2item
  11. Aurora Kinases 3item
  12. Glycoproteins 1 item
  13. MDM2 1 item
  14. EZH2 1 item
  15. mTOR 1 item
  16. AP-1 2item
  17. MMP 1 item
  18. Myosin II ATPases 1 item
  19. FLT3 2item
  20. GSK-3 4item
  21. LPA Receptors 1 item
  22. P-glycoprotein (P-gp) 3item
  23. PLK 7item
  24. Chk 4item
  25. VEGFR 4item
  26. PDGFR 3item
  27. c-Kit 1 item
  28. Bromodomain-containing proteins(BRDs) 1 item
  29. Phosphodiesterases (PDEs) 2item
  30. Hydrolase 1 item
  31. p38 1 item
  32. MEK 1 item
  33. PORCN 1 item
  34. DOT1L 1 item
  35. FGFR 2item
  36. Glucagon-like peptide 1 (GLP-1) receptors 1 item
  37. Sir2-like Family Deacetylases (Sirtuins) 1 item
  38. Smoothened 2item
  39. Eukaryotic elongation factors 1 item
  40. Trk Receptors 1 item
  41. STAT 3item
  42. Microtubules/Tubulins 4item
  43. Estrogen and Related Receptors 1 item
  44. EGFR 6item
  45. Hedgehog 1 item
  46. ROCK 5item
  47. JAK 5item
  48. p300 1 item
  49. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  50. Syk 1 item
  51. DNA-PK 1 item
  52. HSP90 1 item
  53. AMPK 2item
  54. CFTR 3item
  55. TNKS 1 item
  56. ErbB 2item
  57. Toll-like receptors (TLRs) 2item
  58. DNA Methyltransferases 1 item
  59. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  60. ERK 1 item
  61. BMI-1 1 item
  62. PKC 5item
  63. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  64. Lyn 1 item
  65. SGLT 1 item
  66. RAD51 1 item
  67. LRRK2 2item
  68. Voltage-gated Calcium Channels (CaV) 1 item
  69. ALK 1 item
  70. Sphingosine kinases (SphKs) 1 item
  71. PKA 2item
  72. Fatty-acid-binding proteins (FABPs) 1 item
  73. Tie-2 1 item
  74. Free Fatty Acid Receptors 1 item
  75. phosphatases 1 item
  76. Autophagy 2item
  77. ATM/ATR 2item
  78. Farnesyl Diphosphate Synthases 1 item
  79. Melatonin Receptors 1 item
  80. MAGL 1 item
  81. NPY Receptors 1 item
  82. Histamine H1 Receptors 2item
  83. TRP Channel 1 item
  84. MNK 1 item
  85. NO Donors / Precursors 1 item
  86. Glucocorticoid Receptors 1 item
  87. IL Receptors 1 item
  88. 15-lipoxygenases 1 item
  89. Inward Rectifier Potassium (Kir) Channels 1 item
  90. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  91. NMDA receptor 1 item
  92. Aldosterone receptor 1 item
  93. DPP-4 1 item
  94. DREADD Ligands 1 item
  95. p70 rsk 1 item
  96. Microtubule/Tubulin 1 item
  97. p53-MDM2 interaction 1 item
  98. KDR 1 item
  99. p53 3item
  100. c-Fms tyrosine kinase 1 item
  101. insulin 1 item
  102. Ub-conjugating enzyme (E2) complex 1 item
  103. Smoothened receptor 1 item
  104. PPAR 1 item
  105. HDM2 ubiquitin ligase 1 item
  106. Vitamin D receptors (VDRs) 1 item
  107. Antibiotic 1 item
  108. DNA Alkylating 1 item
  109. GLI 1 item
  110. Stem Cell Differentiation 1 item
  111. PP2A/Nkd interaction 1 item
  112. adrenergic receptor 1 item
  113. Ribonucleotide Reductases 1 item
  114. Aryl hydrocarbon receptors (AHRs) 1 item
  115. DCLK2 1 item
  116. phosphatidylinositol kinase 1 item
  117. Adenosine Deaminases 1 item
  118. Histamine receptors 1 item
  119. GluR 1 item
  120. 5-HT receptor 1 item
  121. dopamine receptors 1 item
  122. AMPA receptor 1 item
  123. Flk1 1 item
  124. p21 1 item
  125. RHA 1 item
  126. TRPC channel 1 item
  127. FKBP 1 item
  128. Bcl-w 1 item
  129. PPK 1 item
  130. c-Syk 1 item
  131. CDK1/CyclinB 1 item
  132. FXR 1 item
  133. Vascular Disrupting Agents (VDA) 1 item
  134. Sirtuin 1 item
  135. PIKfyve 1 item
  136. Bax 1 item
  137. NS3/4a Proteases 1 item
  138. p90 S6K 1 item
Related Disease
  1. Acne 1 item
  2. Acute Myelogenous Leukemia 1 item
  3. Acute Myeloid Leukemia 7item
  4. Autoimmune Diseases 1 item
  5. Bladder Cancer 4item
  6. B-lymphoid Malignancies 1 item
  7. Breast Cancer 32item
  8. Cancer 124item
  9. Cholangiocarcinoma 1 item
  10. Chronic Lymphocytic Leukemia 2item
  11. Colon Cancer 10item
  12. Colon Carcinoma 1 item
  13. Colorectal Cancer 13item
  14. Diabetes 3item
  15. Fungal Infection 1 item
  16. Glioblastoma 7item
  17. Glioma 2item
  18. HCV 1 item
  19. Hepatocellular Carcinoma 3item
  20. Immunosuppressive Therapy 1 item
  21. Inflammatory Diseases 3item
  22. Leukemia 6item
  23. Liver Cancer 2item
  24. Lung Cancer 5item
  25. Lymphoma 3item
  26. Mantle Cell Lymphoma 2item
  27. Medulloblastoma 1 item
  28. Melanoma 11item
  29. Mixed Lineage Leukemia 1 item
  30. Multiple Myeloma 5item
  31. Neuroblastoma 2item
  32. Non-small Cell Lung Cancer 6item
  33. Non-small Cell Lung Carcinoma 1 item
  34. Ovarian Cancer 9item
  35. Pain Relief 1 item
  36. Pancreatic Cancer 11item
  37. Pancreatic Carcinoma 2item
  38. Prostate Cancer 12item
  39. Psoriasis 2item
  40. Pulmonary Fibrosis 1 item
  41. Renal Cell Carcinoma 2item
  42. Rheumatoid Arthritis 2item
  43. Sleep Disorders 1 item
  44. Type 2 Diabetes 3item