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Search results for: 'research area cell cycle plk'

Items 31-40 of 170

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  1. 3-Deazaneplanocin A (DZNep) hydrochloride
    A8182 3-Deazaneplanocin A (DZNep) hydrochloride
     1 Citation
    Target: EZH2
    Summary: SAHH and EZH2 inhibitor
      insoluble in EtOH; ≥14.94 mg/mL
  2. AT13387
    A4056 AT13387
    Target: HSP90
    Summary: Hsp90 inhibitor
      insoluble in H2O; ≥13.25 mg/mL
  3. 3-Deazaneplanocin,DZNep
    A1905 3-Deazaneplanocin,DZNep
     6 Citation
    Target: Hydrolase
    Summary: S-adenosylhomocysteine and EZH2 inhibitor
      insoluble in EtOH; ≥17.07 mg/mL
  4. BS-181
    A3266 BS-181
    Target: Cyclin-Dependent Kinases
    Summary: CDK7 inhibitor,highly selective
      Soluble in DMSO
  5. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  6. Plumbagin
    A4456 Plumbagin
    Summary: Anticancer agent
  7. Tubacin
    A4501 Tubacin
     3 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC6 inhibitor,potent,selective,reversible,cell-permeable
      insoluble in EtOH; insoluble in H2O; ≥7.19 mg/mL
  8. PF-4708671
    B2228 PF-4708671
     1 Citation
    Target: p70 rsk
    Summary: P70 S6K1 isoform inhibitor,cell-permeable
      ≥37.8 mg/mL
  9. Gemcitabine
    A8437 Gemcitabine
     1 Citation
    Summary: inhibitor of DNA synthesis
      ≥11.75 mg/mL
  10. Q-VD-OPh
    A1901 Q-VD-OPh
     53 Citation
    Target: Caspases
    Summary: Cell-permeable, irreversible pan-caspase inhibitor
      ≥25.67 mg/mL

Items 31-40 of 170

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  1. Proteases 11item
  2. Apoptosis 18item
  3. Chromatin/Epigenetics 26item
  4. Metabolism 7item
  5. MAPK Signaling 6item
  6. Tyrosine Kinase 14item
  7. DNA Damage/DNA Repair 23item
  8. PI3K/Akt/mTOR Signaling 10item
  9. Microbiology & Virology 3item
  10. Cell Cycle/Checkpoint 28item
  11. Ubiquitination/ Proteasome 9item
  12. JAK/STAT Signaling 12item
  13. TGF-β / Smad Signaling 7item
  14. Angiogenesis 1 item
  15. GPCR/G protein 4item
  16. Stem Cell 12item
  17. Membrane Transporter/Ion Channel 6item
  18. Endocrinology and Hormones 3item
  19. Neuroscience 6item
  20. Obesity, Appetite Control & Diabetes 1 item
  21. Others 11item
  22. Immunology/Inflammation 4item
  23. Vitamin D Related 1 item
  24. NF-κB 1 item
Specificity
  1. Selective 96item
Reversibility
  1. Reversible 11item
  2. Irreversible 7item
Target
  1. Caspases 4item
  2. Cyclin-Dependent Kinases 9item
  3. Proteasome 7item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 12item
  6. Bcl-2 2item
  7. PI3K 3item
  8. Raf 2item
  9. Aurora Kinases 3item
  10. Bcl-xl 1 item
  11. Glycoproteins 1 item
  12. MDM2 1 item
  13. EZH2 1 item
  14. mTOR 2item
  15. AP-1 2item
  16. MMP 1 item
  17. Myosin II ATPases 1 item
  18. FLT3 2item
  19. GSK-3 3item
  20. P-glycoprotein (P-gp) 1 item
  21. PLK 6item
  22. Chk 2item
  23. VEGFR 3item
  24. PDGFR 2item
  25. Bromodomain-containing proteins(BRDs) 1 item
  26. Phosphodiesterases (PDEs) 2item
  27. Hydrolase 1 item
  28. p38 1 item
  29. MEK 2item
  30. PORCN 1 item
  31. DOT1L 1 item
  32. FGFR 2item
  33. Sir2-like Family Deacetylases (Sirtuins) 1 item
  34. Src 1 item
  35. STAT 2item
  36. Estrogen and Related Receptors 1 item
  37. EGFR 6item
  38. ROCK 3item
  39. JAK 5item
  40. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  41. DNA-PK 1 item
  42. HSP90 1 item
  43. AMPK 1 item
  44. CFTR 2item
  45. ErbB 1 item
  46. Toll-like receptors (TLRs) 2item
  47. ERK 1 item
  48. PKC 3item
  49. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  50. RAD51 1 item
  51. LRRK2 2item
  52. Voltage-gated Calcium Channels (CaV) 1 item
  53. ALK 1 item
  54. PKA 1 item
  55. Tie-2 1 item
  56. Free Fatty Acid Receptors 1 item
  57. Autophagy 1 item
  58. ATM/ATR 3item
  59. Farnesyl Diphosphate Synthases 1 item
  60. Melatonin Receptors 1 item
  61. MAGL 1 item
  62. NPY Receptors 1 item
  63. Histamine H1 Receptors 2item
  64. RAR/RXR 1 item
  65. TRP Channel 1 item
  66. DYRK 1 item
  67. MNK 1 item
  68. NO Donors / Precursors 1 item
  69. Glucocorticoid Receptors 1 item
  70. IL Receptors 1 item
  71. 15-lipoxygenases 1 item
  72. Inward Rectifier Potassium (Kir) Channels 1 item
  73. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  74. NMDA receptor 1 item
  75. Aldosterone receptor 1 item
  76. DPP-4 1 item
  77. DREADD Ligands 1 item
  78. p70 rsk 1 item
  79. Microtubule/Tubulin 1 item
  80. p53-MDM2 interaction 1 item
  81. KDR 1 item
  82. p53 3item
  83. c-Fms tyrosine kinase 1 item
  84. insulin 1 item
  85. Ub-conjugating enzyme (E2) complex 1 item
  86. Smoothened receptor 1 item
  87. PPAR 1 item
  88. HDM2 ubiquitin ligase 1 item
  89. Vitamin D receptors (VDRs) 1 item
  90. Antibiotic 1 item
  91. DNA Alkylating 1 item
  92. GLI 1 item
  93. Stem Cell Differentiation 1 item
  94. PP2A/Nkd interaction 1 item
  95. adrenergic receptor 1 item
  96. Ribonucleotide Reductases 1 item
  97. Aryl hydrocarbon receptors (AHRs) 1 item
  98. DCLK2 1 item
  99. phosphatidylinositol kinase 1 item
  100. Lck 1 item
  101. Adenosine Deaminases 1 item
  102. Histamine receptors 1 item
  103. GluR 1 item
  104. 5-HT receptor 1 item
  105. dopamine receptors 1 item
  106. AMPA receptor 1 item
  107. Flk1 1 item
  108. p21 1 item
  109. RHA 1 item
  110. TRPC channel 1 item
  111. FKBP 1 item
  112. Bcl-w 1 item
  113. PPK 1 item
  114. c-Syk 1 item
  115. CDK1/CyclinB 1 item
  116. FXR 1 item
  117. Vascular Disrupting Agents (VDA) 1 item
  118. Sirtuin 1 item
  119. PIKfyve 1 item
  120. Bax 1 item
  121. NS3/4a Proteases 1 item
  122. p90 S6K 1 item
Related Disease
  1. Acne 1 item
  2. Acute Myelogenous Leukemia 1 item
  3. Acute Myeloid Leukemia 4item
  4. Bladder Cancer 4item
  5. B-lymphoid Malignancies 1 item
  6. Breast Cancer 17item
  7. Cancer 81item
  8. Chronic Lymphocytic Leukemia 1 item
  9. Colon Cancer 4item
  10. Colorectal Cancer 7item
  11. Diabetes 2item
  12. Glioblastoma 4item
  13. Glioma 1 item
  14. HCV 1 item
  15. Inflammatory Diseases 2item
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  19. Lymphoma 2item
  20. Mantle Cell Lymphoma 2item
  21. Melanoma 6item
  22. Mixed Lineage Leukemia 1 item
  23. Multiple Myeloma 3item
  24. Non-small Cell Lung Cancer 4item
  25. Ovarian Cancer 4item
  26. Pain Relief 1 item
  27. Pancreatic Cancer 7item
  28. Prostate Cancer 8item
  29. Psoriasis 2item
  30. Pulmonary Fibrosis 1 item
  31. Renal Cell Carcinoma 1 item
  32. Rheumatoid Arthritis 2item
  33. Sleep Disorders 1 item
  34. Type 2 Diabetes 1 item