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  • Search results for: 'research area cell cycle plk'

Search results for: 'research area cell cycle plk'

Items 71-80 of 172

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  1. Lomeguatrib
    A1912 Lomeguatrib
    Target: O6-methylguanine-DNA-methyl-transferase (MGMT)
    Summary: MGMT inhibitor
      ≥50 mg/mL
  2. Gefitinib (ZD1839)
    A8219 Gefitinib (ZD1839)
     3 Citation
    Target: EGFR
    Summary: Selective EGFR inhibitor
      ≥22.34 mg/mL
  3. Bleomycin Sulfate
    A8331 Bleomycin Sulfate
     1 Citation
    Summary: Chemotherapy agent, induces DNA strand break
      ≥125 mg/mL
  4. MG-132
    A2585 MG-132
     26 Citation
    Target: Proteasome
    Summary: Proteasome inhibitor, Cell permeable, reversible
      ≥23.78 mg/mL
  5. LY2090314
    A3570 LY2090314
    Target: GSK-3
    Summary: Potent GSK-3 inhibitor
      insoluble in H2O; ≥91 mg/mL
  6. 740 Y-P
    B5246 740 Y-P
     5 Citation
    Target: PI3K
    Summary: PI 3-kinase activator,cell permeable
      ≥163.54 mg/mL
  7. Natamycin
    A5786 Natamycin
    Summary: Antifungal macrolide polyene
      insoluble in EtOH; insoluble in H2O; ≥16.43 mg/mL
  8. Panobinostat (LBH589)
    A8178 Panobinostat (LBH589)
     10 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in H2O; insoluble in EtOH; ≥17.47 mg/mL
  9. QNZ (EVP4593)
    A4217 QNZ (EVP4593)
     2 Citation
    Summary: Potent NF-κB inhibitor
  10. EPZ004777
    A4170 EPZ004777
    Target: DOT1L
    Summary: DOT1L inhibitor
      ≥27 mg/mL

Items 71-80 of 172

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Category
  1. Proteases 14item
  2. Apoptosis 17item
  3. Chromatin/Epigenetics 27item
  4. Metabolism 4item
  5. MAPK Signaling 4item
  6. Tyrosine Kinase 14item
  7. DNA Damage/DNA Repair 24item
  8. PI3K/Akt/mTOR Signaling 13item
  9. Microbiology & Virology 4item
  10. Cell Cycle/Checkpoint 35item
  11. Ubiquitination/ Proteasome 10item
  12. JAK/STAT Signaling 8item
  13. TGF-β / Smad Signaling 8item
  14. Angiogenesis 1 item
  15. GPCR/G protein 7item
  16. Stem Cell 14item
  17. Membrane Transporter/Ion Channel 7item
  18. Endocrinology and Hormones 1 item
  19. Neuroscience 3item
  20. Obesity, Appetite Control & Diabetes 1 item
  21. Others 9item
  22. Immunology/Inflammation 5item
Reversibility
  1. Reversible 19item
  2. Irreversible 5item
Target
  1. Caspases 6item
  2. Cyclin-Dependent Kinases 13item
  3. Proteasome 4item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 11item
  6. Inhibitor of apoptosis proteins (IAP) 1 item
  7. Akt 1 item
  8. Bcl-2 2item
  9. PI3K 4item
  10. Raf 1 item
  11. Aurora Kinases 4item
  12. Bcl-xl 1 item
  13. Glycoproteins 1 item
  14. MDM2 1 item
  15. EZH2 3item
  16. mTOR 1 item
  17. AP-1 2item
  18. MMP 1 item
  19. Myosin II ATPases 1 item
  20. FLT3 1 item
  21. GSK-3 4item
  22. LPA Receptors 1 item
  23. P-glycoprotein (P-gp) 3item
  24. PLK 3item
  25. Chk 4item
  26. VEGFR 1 item
  27. PDGFR 2item
  28. c-Kit 1 item
  29. Bromodomain-containing proteins(BRDs) 1 item
  30. Phosphodiesterases (PDEs) 1 item
  31. Hydrolase 1 item
  32. p38 1 item
  33. Bcr-Abl 1 item
  34. MEK 2item
  35. PORCN 1 item
  36. DOT1L 1 item
  37. Glucagon-like peptide 1 (GLP-1) receptors 1 item
  38. Smoothened 2item
  39. Eukaryotic elongation factors 1 item
  40. Src 2item
  41. Trk Receptors 1 item
  42. STAT 2item
  43. Microtubules/Tubulins 4item
  44. EGFR 4item
  45. Hedgehog 1 item
  46. Reverse Transcriptases 1 item
  47. ROCK 5item
  48. JAK 2item
  49. p300 1 item
  50. Syk 1 item
  51. DNA-PK 1 item
  52. HSP90 1 item
  53. AMPK 2item
  54. CFTR 3item
  55. TNKS 1 item
  56. ErbB 2item
  57. Toll-like receptors (TLRs) 1 item
  58. DNA Methyltransferases 1 item
  59. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  60. ERK 1 item
  61. BMI-1 1 item
  62. PKC 1 item
  63. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  64. Lyn 1 item
  65. SGLT 1 item
  66. USP 1 item
  67. LRRK2 1 item
  68. Sphingosine kinases (SphKs) 1 item
  69. GTPases 1 item
  70. Fatty-acid-binding proteins (FABPs) 1 item
  71. Tie-2 1 item
  72. Free Fatty Acid Receptors 1 item
  73. phosphatases 1 item
  74. Autophagy 2item
  75. ATM/ATR 3item
  76. CK1 1 item
  77. Farnesyl Diphosphate Synthases 1 item
  78. Melatonin Receptors 1 item
  79. MAGL 1 item
  80. NPY Receptors 1 item
  81. c-Fyn 1 item
  82. Histamine H1 Receptors 1 item
  83. TRP Channel 1 item
  84. Apoptosis Inducers 1 item
  85. NO Donors / Precursors 1 item
  86. IL Receptors 1 item
  87. 15-lipoxygenases 1 item
  88. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  89. Aldosterone receptor 1 item
  90. DPP-4 1 item
  91. DREADD Ligands 1 item
  92. p53-MDM2 interaction 1 item
  93. c-Fms tyrosine kinase 1 item
  94. Ub-conjugating enzyme (E2) complex 1 item
  95. DCLK2 1 item
  96. Lck 1 item
  97. Bcl-w 1 item
  98. FXR 1 item
  99. ATM 1 item
  100. Sirtuin 1 item
  101. PIKfyve 1 item
Reported Experiments
  1. Animal Experiments 151item
  2. Cell Experiments 96item
Related Disease
  1. Acute Myelogenous Leukemia 1 item
  2. Acute Myeloid Leukemia 7item
  3. Autoimmune Diseases 1 item
  4. Bladder Cancer 4item
  5. B-lymphoid Malignancies 1 item
  6. Breast Cancer 34item
  7. Cancer 100item
  8. Cholangiocarcinoma 1 item
  9. Chronic Lymphocytic Leukemia 2item
  10. Colon Cancer 14item
  11. Colon Carcinoma 1 item
  12. Colorectal Cancer 14item
  13. Diabetes 2item
  14. Fungal Infection 1 item
  15. Glioblastoma 7item
  16. Glioma 2item
  17. Hepatocellular Carcinoma 3item
  18. HIV 1 item
  19. Immunosuppressive Therapy 1 item
  20. Inflammatory Diseases 3item
  21. Leukemia 5item
  22. Liver Cancer 2item
  23. Lung Cancer 6item
  24. Lymphoma 4item
  25. Mantle Cell Lymphoma 2item
  26. Medulloblastoma 1 item
  27. Melanoma 11item
  28. Mixed Lineage Leukemia 1 item
  29. Multiple Myeloma 6item
  30. Neuroblastoma 2item
  31. Non-small Cell Lung Cancer 5item
  32. Non-small Cell Lung Carcinoma 1 item
  33. Ovarian Cancer 10item
  34. Pain Relief 1 item
  35. Pancreatic Cancer 11item
  36. Pancreatic Carcinoma 2item
  37. Prostate Cancer 14item
  38. Psoriasis 1 item
  39. Pulmonary Fibrosis 1 item
  40. Renal Cell Carcinoma 2item
  41. Rheumatoid Arthritis 2item
  42. Sleep Disorders 1 item
  43. Type 2 Diabetes 3item