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Search results for: 'research area cell cycle plk'

Items 21-30 of 181

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  1. CYC116
    A4125 CYC116
    Target: Aurora Kinases|FLT3|VEGFR
    Summary: Potent Aurora A/B inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.4 mg/mL
  2. GANT61
    A1615 GANT61
     1 Citation
    Target: GLI
    Summary: GLI antagonist
  3. FH535
    A3413 FH535
    Summary: Wnt/B-catenin inhibitor
      ≥36.1 mg/mL
  4. PluriSIn #1 (NSC 14613)
    A4351 PluriSIn #1 (NSC 14613)
    Target: Stearoyl-CoA 9-desaturase (SCD-1)
    Summary: SCD1 inhibitor
  5. LY2940680
    A8651 LY2940680
    Target: Smoothened receptor
    Summary: Hedgehog/SMO antagonist,inhibits Hh signaling
  6. Wnt-C59
    A8685 Wnt-C59
     2 Citation
    Target: PORCN
    Summary: PORCN inhibitor,highly potent and selective
      .95 mg/mL
      insoluble in H2O; ≥18
  7. Salinomycin
    A3785 Salinomycin
    Target: Antibiotic
    Summary: Polyether ionophore antibiotic;anti-cancer
  8. ICG 001
    A8217 ICG 001
     1 Citation
    Summary: Wnt/β-catenin pathway inhibitor
      ≥27.43 mg/mL
  9. 6,2',4'-Trimethoxyflavone
    A8610 6,2',4'-Trimethoxyflavone
    Target: Aryl hydrocarbon receptors (AHRs)
    Summary: Aryl hydrocarbon receptor antagonist
      insoluble in DMSO
  10. CHIR-99021 (CT99021)
    A3011 CHIR-99021 (CT99021)
     2 Citation
    Target: GSK-3
    Summary: GSK-3 inhibitor, Cell-permeable, ATP-competitive
      ≥23.27 mg/mL

Items 21-30 of 181

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  1. Signaling Pathways 170item
  2. Natural Products 5item
  3. Protein 2item
  4. Kits 1 item
  5. Peptides & Proteins 3item
  6. Lab Reagents 2item
Specificity
  1. Selective 99item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 11item
  2. Irreversible 7item
Target
  1. Caspases 4item
  2. Cyclin-Dependent Kinases 9item
  3. Proteasome 7item
  4. Cathepsins 1 item
  5. Histone Deacetylases (HDACs) 12item
  6. Bcl-2 2item
  7. PI3K 3item
  8. Raf 2item
  9. Aurora Kinases 3item
  10. Bcl-xl 1 item
  11. Glycoproteins 1 item
  12. MDM2 1 item
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  14. mTOR 2item
  15. AP-1 2item
  16. MMP 1 item
  17. Myosin II ATPases 1 item
  18. FLT3 2item
  19. GSK-3 3item
  20. P-glycoprotein (P-gp) 1 item
  21. PLK 6item
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  23. VEGFR 3item
  24. PDGFR 2item
  25. Bromodomain-containing proteins(BRDs) 1 item
  26. Phosphodiesterases (PDEs) 2item
  27. Hydrolase 1 item
  28. p38 1 item
  29. MEK 2item
  30. PORCN 1 item
  31. DOT1L 1 item
  32. FGFR 2item
  33. Sir2-like Family Deacetylases (Sirtuins) 1 item
  34. Src 1 item
  35. STAT 3item
  36. Estrogen and Related Receptors 1 item
  37. EGFR 7item
  38. ROCK 3item
  39. JAK 5item
  40. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  41. DNA-PK 1 item
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  47. Toll-like receptors (TLRs) 2item
  48. ERK 1 item
  49. PKC 3item
  50. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  51. RAD51 1 item
  52. LRRK2 2item
  53. Voltage-gated Calcium Channels (CaV) 1 item
  54. ALK 1 item
  55. PKA 1 item
  56. Tie-2 1 item
  57. Free Fatty Acid Receptors 1 item
  58. Autophagy 1 item
  59. ATM/ATR 3item
  60. Farnesyl Diphosphate Synthases 1 item
  61. Melatonin Receptors 1 item
  62. Peroxynitrite 1 item
  63. MAGL 1 item
  64. NPY Receptors 1 item
  65. Histamine H1 Receptors 3item
  66. RAR/RXR 1 item
  67. TRP Channel 1 item
  68. DYRK 1 item
  69. MNK 1 item
  70. NO Donors / Precursors 1 item
  71. Glucocorticoid Receptors 1 item
  72. IL Receptors 1 item
  73. 15-lipoxygenases 1 item
  74. Inward Rectifier Potassium (Kir) Channels 2item
  75. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  76. NMDA receptor 1 item
  77. Aldosterone receptor 1 item
  78. DPP-4 1 item
  79. DREADD Ligands 1 item
  80. p70 rsk 1 item
  81. Microtubule/Tubulin 1 item
  82. p53-MDM2 interaction 1 item
  83. KDR 1 item
  84. p53 3item
  85. c-Fms tyrosine kinase 1 item
  86. insulin 1 item
  87. Ub-conjugating enzyme (E2) complex 1 item
  88. Smoothened receptor 1 item
  89. PPAR 1 item
  90. HDM2 ubiquitin ligase 1 item
  91. Glucosidases 1 item
  92. Vitamin D receptors (VDRs) 1 item
  93. Antibiotic 1 item
  94. DNA Alkylating 1 item
  95. GLI 1 item
  96. Stem Cell Differentiation 1 item
  97. PP2A/Nkd interaction 1 item
  98. adrenergic receptor 1 item
  99. Ribonucleotide Reductases 1 item
  100. Aryl hydrocarbon receptors (AHRs) 1 item
  101. DCLK2 1 item
  102. phosphatidylinositol kinase 1 item
  103. Lck 1 item
  104. Adenosine Deaminases 1 item
  105. Histamine receptors 1 item
  106. GluR 1 item
  107. 5-HT receptor 1 item
  108. dopamine receptors 1 item
  109. AMPA receptor 1 item
  110. Flk1 1 item
  111. p21 1 item
  112. RHA 1 item
  113. TRPC channel 1 item
  114. FKBP 1 item
  115. Bcl-w 1 item
  116. PPK 1 item
  117. c-Syk 1 item
  118. CDK1/CyclinB 1 item
  119. glucose uptake 1 item
  120. FXR 1 item
  121. Vascular Disrupting Agents (VDA) 1 item
  122. Sirtuin 1 item
  123. PIKfyve 1 item
  124. Bax 1 item
  125. NS3/4a Proteases 1 item
  126. p90 S6K 1 item
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  6. Breast Cancer 17item
  7. Cancer 82item
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  26. Pain Relief 1 item
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