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  • Search results for: 'research area cell cycle rock'

Search results for: 'research area cell cycle rock'

Items 21-30 of 135

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  1. Palbociclib (PD0332991) Isethionate
    A8335 Palbociclib (PD0332991) Isethionate
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥28.7 mg/mL
  2. BMS265246
    A8385 BMS265246
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/2 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL
  3. Dinaciclib (SCH727965)
    A8412 Dinaciclib (SCH727965)
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK inhibitor
  4. LEE011
    A8641 LEE011
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥10.88 mg/mL
  5. Rigosertib sodium salt
    A1404 Rigosertib sodium salt
     1 Citation
    Target: PLK
    Summary: Plk1 inhibitor
      ≥23.65 mg/mL
  6. BI 2536
    A3965 BI 2536
     1 Citation
    Target: PLK|Bromodomain-containing proteins(BRDs)
    Summary: Plk1 inhibitor,potent and ATP-competitive
      insoluble in H2O; ≥13.04 mg/mL
  7. Hesperadin
    A4118 Hesperadin
     1 Citation
    Target: Aurora Kinases
    Summary: Aurora B kinase inhibitor
      ≥25.85 mg/mL
  8. Barasertib (AZD1152-HQPA)
    A4112 Barasertib (AZD1152-HQPA)
     3 Citation
    Target: Aurora Kinases
    Summary: Aurora Kinase B inhibitor, Potent and selective
      ≥25.4 mg/mL
  9. CYC116
    A4125 CYC116
    Target: Aurora Kinases|FLT3|VEGFR
    Summary: Potent Aurora A/B inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.4 mg/mL
  10. Aurora A Inhibitor I
    A4126 Aurora A Inhibitor I
    Target: Aurora Kinases
    Summary: Aurora A inhibitor
      ≥29.4 mg/mL

Items 21-30 of 135

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  1. Category Signaling Pathways Remove This Item
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Category
  1. Proteases 8item
  2. Apoptosis 16item
  3. Chromatin/Epigenetics 23item
  4. Metabolism 3item
  5. MAPK Signaling 3item
  6. Tyrosine Kinase 13item
  7. DNA Damage/DNA Repair 22item
  8. PI3K/Akt/mTOR Signaling 7item
  9. Cell Cycle/Checkpoint 36item
  10. Ubiquitination/ Proteasome 9item
  11. JAK/STAT Signaling 11item
  12. TGF-β / Smad Signaling 4item
  13. GPCR/G protein 3item
  14. Stem Cell 16item
  15. Membrane Transporter/Ion Channel 2item
  16. Others 4item
  17. Immunology/Inflammation 1 item
Specificity
  1. Selective 100item
Reversibility
  1. Reversible 11item
  2. Irreversible 4item
Target
  1. Caspases 3item
  2. Cyclin-Dependent Kinases 14item
  3. Proteasome 3item
  4. Histone Deacetylases (HDACs) 8item
  5. Inhibitor of apoptosis proteins (IAP) 1 item
  6. Akt 1 item
  7. Bcl-2 2item
  8. PI3K 2item
  9. Raf 1 item
  10. Aurora Kinases 4item
  11. Glycoproteins 1 item
  12. MDM2 1 item
  13. EZH2 3item
  14. AP-1 1 item
  15. FLT3 1 item
  16. GSK-3 2item
  17. LPA Receptors 1 item
  18. P-glycoprotein (P-gp) 3item
  19. PLK 6item
  20. Chk 3item
  21. VEGFR 4item
  22. PDGFR 2item
  23. c-Kit 1 item
  24. Bromodomain-containing proteins(BRDs) 1 item
  25. p38 1 item
  26. MEK 1 item
  27. PORCN 1 item
  28. DOT1L 1 item
  29. FGFR 1 item
  30. Deubiquitinating enzymes (DUBs) 1 item
  31. Smoothened 2item
  32. Trk Receptors 1 item
  33. STAT 3item
  34. Microtubules/Tubulins 4item
  35. EGFR 5item
  36. Hedgehog 1 item
  37. ROCK 1 item
  38. JAK 4item
  39. p300 1 item
  40. DNA-PK 1 item
  41. HSP90 1 item
  42. TNKS 1 item
  43. ErbB 2item
  44. DNA Methyltransferases 1 item
  45. BMI-1 1 item
  46. PKC 3item
  47. Lyn 1 item
  48. SGLT 1 item
  49. RAD51 1 item
  50. ALK 1 item
  51. Sphingosine kinases (SphKs) 1 item
  52. PKA 1 item
  53. Autophagy 2item
  54. ATM/ATR 3item
  55. CK1 1 item
  56. Farnesyl Diphosphate Synthases 1 item
  57. MAGL 1 item
  58. Apoptosis Inducers 1 item
  59. MNK 1 item
  60. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  61. p70 rsk 1 item
  62. Microtubule/Tubulin 1 item
  63. p53-MDM2 interaction 1 item
  64. KDR 1 item
  65. p53 2item
  66. insulin 1 item
  67. Ub-conjugating enzyme (E2) complex 1 item
  68. Smoothened receptor 1 item
  69. HDM2 ubiquitin ligase 1 item
  70. Antibiotic 1 item
  71. DNA Alkylating 1 item
  72. GLI 1 item
  73. Ribonucleotide Reductases 1 item
  74. Flk1 1 item
  75. RHA 1 item
  76. Bcl-w 1 item
  77. PPK 1 item
  78. c-Syk 1 item
  79. CDK1/CyclinB 1 item
  80. Bax 1 item
Reported Experiments
  1. Animal Experiments 124item
  2. Cell Experiments 81item