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  • Search results for: 'research area dna damage atm kinase'

Search results for: 'research area dna damage atm kinase'

Items 101-110 of 229

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  1. Nintedanib (BIBF 1120)
    A8252 Nintedanib (BIBF 1120)
     3 Citation
    Target: VEGFR|PDGFR|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
  2. PD 173074
    A8253 PD 173074
    Target: VEGFR|FGFR
    Summary: FGFR inhibitor
      ≥26.18 mg/mL
  3. PHA-793887
    A5459 PHA-793887
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Pan-Cdk inhibitor
      insoluble in H2O; ≥18.05 mg/mL
  4. Palbociclib (PD0332991) Isethionate
    A8335 Palbociclib (PD0332991) Isethionate
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥28.7 mg/mL
  5. BMS265246
    A8385 BMS265246
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/2 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL
  6. LEE011
    A8641 LEE011
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥10.88 mg/mL
  7. AT7519 Hydrochloride
    A3197 AT7519 Hydrochloride
    Target: Cyclin-Dependent Kinases
    Summary: Multi-CDK inhibitor
      ≥29.93 mg/mL
  8. KU-0060648
    A1769 KU-0060648
     1 Citation
    Target: PI3K|DNA-PK
    Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
  9. Beta-Lapachone
    B2290 Beta-Lapachone
    Target: Topoisomerases
    Summary: DNA topoisomerase I inhibitor,selective
      insoluble in H2O; ≥10.85 mg/mL
  10. Gemcitabine
    A8437 Gemcitabine
     1 Citation
    Summary: inhibitor of DNA synthesis
      ≥11.75 mg/mL

Items 101-110 of 229

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  1. Category Signaling Pathways Remove This Item
  2. Related Disease Cancer Remove This Item
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Category
  1. Proteases 1 item
  2. Apoptosis 7item
  3. Chromatin/Epigenetics 29item
  4. MAPK Signaling 14item
  5. Tyrosine Kinase 79item
  6. DNA Damage/DNA Repair 28item
  7. PI3K/Akt/mTOR Signaling 26item
  8. Microbiology & Virology 2item
  9. Cell Cycle/Checkpoint 52item
  10. Ubiquitination/ Proteasome 3item
  11. JAK/STAT Signaling 25item
  12. TGF-β / Smad Signaling 16item
  13. GPCR/G protein 2item
  14. Stem Cell 3item
  15. Others 6item
  16. Immunology/Inflammation 2item
Specificity
  1. Selective 182item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 18item
  2. Irreversible 6item
Target
  1. Cyclin-Dependent Kinases 22item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 5item
  4. PI3K 12item
  5. Raf 9item
  6. Aurora Kinases 16item
  7. CSF-1R 4item
  8. mTOR 6item
  9. AP-1 1 item
  10. FLT3 7item
  11. GSK-3 4item
  12. PLK 5item
  13. Chk 4item
  14. Eph Receptors 3item
  15. VEGFR 27item
  16. PDGFR 17item
  17. c-Kit 9item
  18. RET 4item
  19. Bromodomain-containing proteins(BRDs) 1 item
  20. Thymidylate Synthase 1 item
  21. p38 3item
  22. JNK 1 item
  23. SGK 2item
  24. Bcr-Abl 6item
  25. MEK 2item
  26. FGFR 9item
  27. Pim 3item
  28. Ribosomal s6 kinases (RSK) 1 item
  29. MET 5item
  30. Src 8item
  31. Trk Receptors 1 item
  32. STAT 4item
  33. EGFR 13item
  34. PAK 3item
  35. FAK 4item
  36. BMP and Other Activin Receptors 1 item
  37. JAK 8item
  38. Syk 3item
  39. DNA-PK 5item
  40. Topoisomerases 6item
  41. ErbB 4item
  42. DNA Methyltransferases 3item
  43. ERK 2item
  44. c-MET 5item
  45. PKC 8item
  46. Ubiquitin-specific proteases 1 item
  47. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  48. Lyn 1 item
  49. HER2 1 item
  50. Pyk2 3item
  51. Insulin and Insulin-like Receptors 2item
  52. ALK 5item
  53. ROS1 1 item
  54. Sphingosine kinases (SphKs) 1 item
  55. PKG 2item
  56. PKA 4item
  57. Myosin light chain kinases (MLCKs) 1 item
  58. MELK 1 item
  59. Insulin-like growth factors (IGFs) 1 item
  60. MK2 1 item
  61. Tie-2 1 item
  62. RSK 1 item
  63. ATM/ATR 3item
  64. CK1 1 item
  65. Farnesyl Diphosphate Synthases 1 item
  66. CK2 1 item
  67. HIPK2 1 item
  68. HIPK3 1 item
  69. BLM 1 item
  70. Synthases/Synthetases 1 item
  71. MAGL 1 item
  72. P110 1 item
  73. Hck 1 item
  74. RNA Polymerases 1 item
  75. MNK 1 item
  76. Insulin Receptors 1 item
  77. IRG-1R 1 item
  78. eEF-2 1 item
  79. Cdc7 1 item
  80. CMV 1 item
  81. ZAP-70 1 item
  82. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  83. Cytidine deaminases 1 item
  84. c-RET 2item
  85. p70 rsk 1 item
  86. VEGFR3/FLT4 1 item
  87. NTRK1/TRKA 1 item
  88. CSF-1R/c-Fms 1 item
  89. TAM kinase 1 item
  90. KDR 1 item
  91. AXL 1 item
  92. insulin 1 item
  93. ErbB-2 1 item
  94. PDK-1 1 item
  95. Prk 1 item
  96. Flk1 2item
  97. tropomyosin receptor kinase 1 item
  98. SK 1 item
  99. PPK 1 item
  100. c-Syk 1 item
  101. CDK1/CyclinB 1 item
  102. PIM1 kinase 1 item
  103. phospholipase A2 1 item
Reported Experiments
  1. Animal Experiments 215item
  2. Cell Experiments 144item