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  • Search results for: 'research area dna damage atm kinase'

Search results for: 'research area dna damage atm kinase'

Items 631-640 of 763

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  1. Enzastaurin (LY317615)
    A1670 Enzastaurin (LY317615)
     2 Citation
    Target: PKC
    Summary: PKC beta inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
  2. Zoledronic Acid
    A1352 Zoledronic Acid
    Target: Farnesyl Diphosphate Synthases
    Summary: Potent nitrogen-containing bisphosphonates
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  3. PF-477736
    B1437 PF-477736
    Target: Chk
    Summary: Chk1 inhibitor
      insoluble in EtOH; insoluble in H2O; ≥5.24 mg/mL
  4. EMD638683
    A3389 EMD638683
     4 Citation
    Target: SGK
    Summary: SGK1 inhibitor
      insoluble in H2O; ≥18.2 mg/mL
  5. LY3023414
    B6099 LY3023414
    Target: Akt|PI3K|mTOR|DNA-PK
    Summary: class I PI3K isoforms, mTOR and DNA-PK inhibitor
      ≥40.6 mg/mL
  6. 2',3',5'-triacetyl-5-Azacytidine
    C4119 2',3',5'-triacetyl-5-Azacytidine
    Summary: prodrug form of 5-azacytidine, a DNA methyltransferase inhibitor
      ≤30 mg/mL
  7. L189
    B7426 L189
    Target: DNA Ligases
    Summary: inhibitor of human DNA ligases I, III and IV
      ≥62.5 mg/mL
  8. Pexmetinib (ARRY-614)
    B6012 Pexmetinib (ARRY-614)
    Target: p38|Tie-2
    Summary: dual inhibitor of p38 MAPK and Tie2/Tek receptor tyrosine kinase
      insoluble in H2O; ≥107.6 mg/mL
  9. Chelerythrine Chloride
    A3306 Chelerythrine Chloride
    Target: PKC
    Summary: PKC antagonist
      insoluble in H2O; ≥19.2 mg/mL
  10. NVP 231
    B1235 NVP 231
    Summary: CerK inhibitor

Items 631-640 of 763

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Category
  1. Proteases 5item
  2. Apoptosis 30item
  3. Chromatin/Epigenetics 76item
  4. Metabolism 5item
  5. MAPK Signaling 61item
  6. Tyrosine Kinase 221item
  7. DNA Damage/DNA Repair 76item
  8. PI3K/Akt/mTOR Signaling 86item
  9. Microbiology & Virology 20item
  10. Cell Cycle/Checkpoint 119item
  11. Ubiquitination/ Proteasome 8item
  12. JAK/STAT Signaling 65item
  13. TGF-β / Smad Signaling 70item
  14. Angiogenesis 6item
  15. GPCR/G protein 6item
  16. Stem Cell 12item
  17. Membrane Transporter/Ion Channel 5item
  18. Cancer Biology 7item
  19. Endocrinology and Hormones 1 item
  20. Neuroscience 6item
  21. Other Signal Transduction 5item
  22. Others 44item
  23. Immunology/Inflammation 12item
Specificity
  1. Selective 274item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 24item
  2. Irreversible 8item
Target
  1. Cyclin-Dependent Kinases 27item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 5item
  4. PI3K 18item
  5. Raf 10item
  6. Aurora Kinases 21item
  7. CSF-1R 4item
  8. mTOR 10item
  9. AP-1 1 item
  10. FLT3 13item
  11. GSK-3 9item
  12. PLK 6item
  13. Chk 5item
  14. Eph Receptors 3item
  15. VEGFR 30item
  16. PDGFR 22item
  17. c-Kit 12item
  18. RET 4item
  19. IRAK 3item
  20. Bromodomain-containing proteins(BRDs) 1 item
  21. Thymidylate Synthase 1 item
  22. p38 6item
  23. PKB 1 item
  24. JNK 2item
  25. SGK 2item
  26. Bcr-Abl 13item
  27. MEK 4item
  28. FGFR 12item
  29. Pim 4item
  30. Voltage-gated Sodium (NaV) Channels 1 item
  31. Ribosomal s6 kinases (RSK) 1 item
  32. MET 5item
  33. Src 17item
  34. Trk Receptors 2item
  35. STAT 6item
  36. Estrogen and Related Receptors 1 item
  37. EGFR 18item
  38. ROCK 7item
  39. BTK 1 item
  40. PAK 3item
  41. FAK 4item
  42. BMP and Other Activin Receptors 2item
  43. JAK 16item
  44. Syk 5item
  45. DNA-PK 8item
  46. AMPK 2item
  47. PDHK 1 item
  48. Topoisomerases 9item
  49. ErbB 4item
  50. S6 kinases 1 item
  51. Adenosine Kinases 2item
  52. DNA Methyltransferases 3item
  53. ERK 4item
  54. Kinases 1 item
  55. c-MET 5item
  56. PKC 12item
  57. Ubiquitin-specific proteases 1 item
  58. Ca2 /calmodulin-dependent protein kinases (CaMKs) 6item
  59. Lyn 2item
  60. HER2 2item
  61. Pyk2 3item
  62. LRRK2 5item
  63. Insulin and Insulin-like Receptors 3item
  64. ALK 6item
  65. ROS1 1 item
  66. Sphingosine kinases (SphKs) 2item
  67. PKG 2item
  68. PKA 5item
  69. Myosin light chain kinases (MLCKs) 2item
  70. CaM-KK 1 item
  71. MELK 1 item
  72. Insulin-like growth factors (IGFs) 1 item
  73. Clk 1 item
  74. NUAK1 1 item
  75. NUAK2 1 item
  76. MK2 2item
  77. Fatty-acid-binding proteins (FABPs) 1 item
  78. Angiotensin-Converting Enzymes (ACEs) 1 item
  79. Tie-2 2item
  80. RSK 2item
  81. ATM/ATR 5item
  82. CK1 1 item
  83. Farnesyl Diphosphate Synthases 1 item
  84. CK2 3item
  85. HIPK2 1 item
  86. HIPK3 1 item
  87. HIV Integrases 1 item
  88. P2X Receptors 1 item
  89. BLM 1 item
  90. HSV 2item
  91. Synthases/Synthetases 2item
  92. MAGL 1 item
  93. c-Fyn 1 item
  94. TAK1 1 item
  95. Histamine H1 Receptors 1 item
  96. P110 1 item
  97. Hck 2item
  98. RNA Polymerases 1 item
  99. MNK 1 item
  100. 5-Lipoxygenases 1 item
  101. Insulin Receptors 1 item
  102. IRG-1R 1 item
  103. eEF-2 1 item
  104. Cdc7 1 item
  105. CMV 1 item
  106. ZAP-70 1 item
  107. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  108. Cytidine deaminases 1 item
  109. c-RET 3item
  110. p70 rsk 2item
  111. VEGFR3/FLT4 1 item
  112. NTRK1/TRKA 1 item
  113. CSF-1R/c-Fms 1 item
  114. TAM kinase 1 item
  115. KDR 1 item
  116. Fyn kinase 1 item
  117. Abl kinases 1 item
  118. AXL 1 item
  119. p53 1 item
  120. c-Fms tyrosine kinase 1 item
  121. insulin 1 item
  122. PPAR 1 item
  123. haspin kinase 1 item
  124. STK 1 item
  125. MSK 1 item
  126. Lyn kinase 1 item
  127. Mer tyrosine kinase 1 item
  128. ErbB-2 1 item
  129. PDK-1 1 item
  130. Histone Acetyltransferases (HATs) 1 item
  131. Prk 1 item
  132. ITK 1 item
  133. NUAK 1 item
  134. DCLK2 1 item
  135. PTK 2item
  136. phosphatidylinositol kinase 1 item
  137. Lck 1 item
  138. prolactin secretion 1 item
  139. gonadotropin release 1 item
  140. Flk1 2item
  141. DNA Ligases 1 item
  142. glutamate release 1 item
  143. FGR 1 item
  144. YES 2item
  145. Fyn 2item
  146. ARG 1 item
  147. TRPC channel 1 item
  148. PKD 1 item
  149. enoyl-acyl-carrier protein reductase 1 item
  150. Rho-kinase 1 item
  151. tropomyosin receptor kinase 1 item
  152. SK 1 item
  153. PPK 1 item
  154. c-Syk 1 item
  155. CDK1/CyclinB 1 item
  156. PIM1 kinase 1 item
  157. phospholipase A2 1 item
  158. ATM 2item
  159. Sirtuin 1 item
  160. PIKfyve 1 item
  161. Insulin Receptor 1 item
Reported Experiments
  1. Animal Experiments 323item
  2. Cell Experiments 241item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 16item
  3. Acute Renal Failure 1 item
  4. Adrenocortical Carcinoma 2item
  5. Advanced Renal Cell Carcinoma 1 item
  6. Bladder Cancer 5item
  7. Bladder Carcinoma 2item
  8. Bladder Diseases 1 item
  9. B-lymphoid Malignancies 1 item
  10. Breast Cancer 50item
  11. Cancer 229item
  12. Cervical Cancer 5item
  13. Cholangiocarcinoma 2item
  14. Chronic Lymphocytic Leukemia 2item
  15. Clear Cell Renal Cell Carcinoma 1 item
  16. Colon Cancer 24item
  17. Colon Carcinoma 2item
  18. Colorectal Cancer 22item
  19. Glioblastoma 18item
  20. Glioma 6item
  21. Hepatocellular Carcinoma 5item
  22. HIV 1 item
  23. HIV Infections 2item
  24. Immunological Diseases 1 item
  25. Inflammatory Bowel Disease 1 item
  26. Inflammatory Diseases 5item
  27. Leukemia 13item
  28. Liver Cancer 3item
  29. Lung Cancer 17item
  30. Lung Carcinoma 3item
  31. Lymphoma 11item
  32. Mantle Cell Lymphoma 1 item
  33. Melanoma 16item
  34. Multiple Myeloma 7item
  35. Myelofibrosis 1 item
  36. Myeloma 2item
  37. Neuroblastoma 3item
  38. Non-small Cell Lung Cancer 5item
  39. Non-small Cell Lung Carcinoma 1 item
  40. Ovarian Cancer 19item
  41. Pancreatic Cancer 24item
  42. Prostate Cancer 21item
  43. Psoriasis 1 item
  44. Pulmonary Arterial Hypertension 1 item
  45. Renal Cancer 3item
  46. Renal Cell Carcinoma 5item
  47. Rheumatoid Arthritis 5item
  48. Sarcoma 1 item
  49. Squamous Cell Carcinoma 1 item
  50. Testicular Cancer 2item
  51. Thyroid Cancer 5item
  52. Type 2 Diabetes 3item