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  • Search results for: 'research area dna damage atm kinase'

Search results for: 'research area dna damage atm kinase'

Items 1-10 of 323

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  1. KU-60019
    A8336 KU-60019
     2 Citation
    Target: ATM/ATR
    Summary: ATM kinase inhibitor,potent and selective
      ≥27.4 mg/mL
  2. Tie2 kinase inhibitor
    A5979 Tie2 kinase inhibitor
    Target: Tie-2
    Summary: Tie-2(Tie2 ) inhibitor
      ≥22 mg/mL
  3. NU7441 (KU-57788)
    A8315 NU7441 (KU-57788)
     4 Citation
    Target: PI3K|DNA-PK
    Summary: DNA-PK inhibitor
      insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
  4. Gemcitabine HCl
    A1402 Gemcitabine HCl
    Summary: Inhibits DNA synthesis,deoxycytidine analog
      ≥10.1 mg/mL
  5. NU 7026
    A8649 NU 7026
    Target: PI3K|DNA-PK|ATM
    Summary: DNPK inhibitor,ATP-competitive and potent
      insoluble in EtOH; insoluble in DMSO; insoluble in H2O
  6. Cytarabine
    A8405 Cytarabine
     1 Citation
    Summary: cytotoxic agent, blocks DNA synthesis
      insoluble in EtOH; ≥28.6 mg/mL
  7. Carboplatin
    A2171 Carboplatin
    Summary: Antitumor agent that forms platinum-DNA adducts.
      insoluble in ETOH; ≥9.28 mg/mL
  8. Oxaliplatin
    A8648 Oxaliplatin
     3 Citation
    Summary: Antitumor agent
      insoluble in EtOH; ≥37.25 mg/mL
  9. Fludarabine Phosphate (Fludara)
    A8317 Fludarabine Phosphate (Fludara)
     2 Citation
    Target: STAT
    Summary: Inhibits STAT1 activation and DNA synthesis
      insoluble in EtOH; ≥17.6 mg/mL
  10. Bleomycin Sulfate
    A8331 Bleomycin Sulfate
     1 Citation
    Summary: Chemotherapy agent, induces DNA strand break
      ≥125 mg/mL

Items 1-10 of 323

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Category
  1. Proteases 2item
  2. Apoptosis 8item
  3. Chromatin/Epigenetics 36item
  4. Metabolism 1 item
  5. MAPK Signaling 22item
  6. Tyrosine Kinase 105item
  7. DNA Damage/DNA Repair 34item
  8. PI3K/Akt/mTOR Signaling 42item
  9. Microbiology & Virology 5item
  10. Cell Cycle/Checkpoint 57item
  11. Ubiquitination/ Proteasome 3item
  12. JAK/STAT Signaling 33item
  13. TGF-β / Smad Signaling 33item
  14. Angiogenesis 1 item
  15. GPCR/G protein 4item
  16. Stem Cell 5item
  17. Membrane Transporter/Ion Channel 4item
  18. Endocrinology and Hormones 1 item
  19. Neuroscience 2item
  20. Others 13item
  21. Immunology/Inflammation 2item
Specificity
  1. Selective 240item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 22item
  2. Irreversible 6item
Target
  1. Cyclin-Dependent Kinases 22item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 5item
  4. PI3K 16item
  5. Raf 10item
  6. Aurora Kinases 18item
  7. CSF-1R 4item
  8. mTOR 9item
  9. AP-1 1 item
  10. FLT3 13item
  11. GSK-3 8item
  12. PLK 6item
  13. Chk 5item
  14. Eph Receptors 2item
  15. VEGFR 30item
  16. PDGFR 22item
  17. c-Kit 12item
  18. RET 4item
  19. IRAK 1 item
  20. Bromodomain-containing proteins(BRDs) 1 item
  21. Thymidylate Synthase 1 item
  22. p38 6item
  23. PKB 1 item
  24. JNK 1 item
  25. SGK 1 item
  26. Bcr-Abl 11item
  27. MEK 3item
  28. FGFR 12item
  29. Pim 3item
  30. Voltage-gated Sodium (NaV) Channels 1 item
  31. MET 5item
  32. Src 14item
  33. Trk Receptors 2item
  34. STAT 6item
  35. Estrogen and Related Receptors 1 item
  36. EGFR 16item
  37. ROCK 5item
  38. BTK 1 item
  39. PAK 3item
  40. FAK 4item
  41. BMP and Other Activin Receptors 2item
  42. JAK 14item
  43. Syk 5item
  44. DNA-PK 7item
  45. AMPK 2item
  46. PDHK 1 item
  47. Topoisomerases 8item
  48. ErbB 4item
  49. S6 kinases 1 item
  50. Adenosine Kinases 2item
  51. DNA Methyltransferases 2item
  52. ERK 4item
  53. c-MET 5item
  54. PKC 11item
  55. Ubiquitin-specific proteases 1 item
  56. Ca2 /calmodulin-dependent protein kinases (CaMKs) 5item
  57. Lyn 2item
  58. HER2 2item
  59. Pyk2 3item
  60. LRRK2 5item
  61. Insulin and Insulin-like Receptors 3item
  62. ALK 6item
  63. ROS1 1 item
  64. Sphingosine kinases (SphKs) 2item
  65. PKG 1 item
  66. PKA 4item
  67. Myosin light chain kinases (MLCKs) 1 item
  68. MELK 1 item
  69. Insulin-like growth factors (IGFs) 1 item
  70. MK2 2item
  71. Fatty-acid-binding proteins (FABPs) 1 item
  72. Angiotensin-Converting Enzymes (ACEs) 1 item
  73. Tie-2 2item
  74. RSK 2item
  75. ATM/ATR 3item
  76. Farnesyl Diphosphate Synthases 1 item
  77. CK2 2item
  78. HIPK2 1 item
  79. HIPK3 1 item
  80. HIV Integrases 1 item
  81. P2X Receptors 1 item
  82. BLM 1 item
  83. HSV 1 item
  84. Synthases/Synthetases 2item
  85. MAGL 1 item
  86. Histamine H1 Receptors 1 item
  87. P110 1 item
  88. Hck 2item
  89. RNA Polymerases 1 item
  90. MNK 1 item
  91. 5-Lipoxygenases 1 item
  92. Insulin Receptors 1 item
  93. IRG-1R 1 item
  94. eEF-2 1 item
  95. Cdc7 1 item
  96. CMV 1 item
  97. ZAP-70 1 item
  98. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  99. Cytidine deaminases 1 item
  100. c-RET 3item
  101. p70 rsk 2item
  102. VEGFR3/FLT4 1 item
  103. NTRK1/TRKA 1 item
  104. CSF-1R/c-Fms 1 item
  105. TAM kinase 1 item
  106. KDR 1 item
  107. Fyn kinase 1 item
  108. AXL 1 item
  109. c-Fms tyrosine kinase 1 item
  110. insulin 1 item
  111. PPAR 1 item
  112. MSK 1 item
  113. Lyn kinase 1 item
  114. Mer tyrosine kinase 1 item
  115. ErbB-2 1 item
  116. PDK-1 1 item
  117. Histone Acetyltransferases (HATs) 1 item
  118. Prk 1 item
  119. ITK 1 item
  120. NUAK 1 item
  121. DCLK2 1 item
  122. PTK 2item
  123. phosphatidylinositol kinase 1 item
  124. prolactin secretion 1 item
  125. gonadotropin release 1 item
  126. Flk1 2item
  127. glutamate release 1 item
  128. FGR 1 item
  129. YES 2item
  130. Fyn 2item
  131. ARG 1 item
  132. TRPC channel 1 item
  133. PKD 1 item
  134. enoyl-acyl-carrier protein reductase 1 item
  135. Rho-kinase 1 item
  136. tropomyosin receptor kinase 1 item
  137. SK 1 item
  138. PPK 1 item
  139. c-Syk 1 item
  140. CDK1/CyclinB 1 item
  141. PIM1 kinase 1 item
  142. phospholipase A2 1 item
  143. ATM 1 item
  144. Sirtuin 1 item
  145. PIKfyve 1 item
  146. Insulin Receptor 1 item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 15item
  3. Acute Renal Failure 1 item
  4. Adrenocortical Carcinoma 2item
  5. Advanced Renal Cell Carcinoma 1 item
  6. Bladder Cancer 5item
  7. Bladder Carcinoma 2item
  8. Bladder Diseases 1 item
  9. B-lymphoid Malignancies 1 item
  10. Breast Cancer 48item
  11. Cancer 215item
  12. Cervical Cancer 5item
  13. Cholangiocarcinoma 2item
  14. Chronic Lymphocytic Leukemia 2item
  15. Clear Cell Renal Cell Carcinoma 1 item
  16. Colon Cancer 21item
  17. Colon Carcinoma 2item
  18. Colorectal Cancer 21item
  19. Glioblastoma 18item
  20. Glioma 6item
  21. Hepatocellular Carcinoma 5item
  22. HIV 1 item
  23. HIV Infections 2item
  24. Immunological Diseases 1 item
  25. Inflammatory Bowel Disease 1 item
  26. Inflammatory Diseases 4item
  27. Leukemia 13item
  28. Liver Cancer 3item
  29. Lung Cancer 16item
  30. Lung Carcinoma 3item
  31. Lymphoma 11item
  32. Mantle Cell Lymphoma 1 item
  33. Melanoma 15item
  34. Multiple Myeloma 5item
  35. Myelofibrosis 1 item
  36. Myeloma 2item
  37. Neuroblastoma 3item
  38. Non-small Cell Lung Cancer 5item
  39. Non-small Cell Lung Carcinoma 1 item
  40. Ovarian Cancer 19item
  41. Pancreatic Cancer 24item
  42. Prostate Cancer 18item
  43. Psoriasis 1 item
  44. Pulmonary Arterial Hypertension 1 item
  45. Renal Cancer 3item
  46. Renal Cell Carcinoma 5item
  47. Rheumatoid Arthritis 5item
  48. Sarcoma 1 item
  49. Squamous Cell Carcinoma 1 item
  50. Testicular Cancer 2item
  51. Thyroid Cancer 5item
  52. Type 2 Diabetes 3item