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  • Search results for: 'research area dna damage atm kinase'

Search results for: 'research area dna damage atm kinase'

Items 91-100 of 231

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  1. ENMD-2076
    A4130 ENMD-2076
    Target: Aurora Kinases|FLT3|RET|Src|VEGFR3/FLT4|NTRK1/TRKA|CSF-1R/c-Fms
    Summary: Selective Aurora A/Flt3 inhibitor
      insoluble in H2O; ≥18.75 mg/mL
  2. AZD-5438
    A8326 AZD-5438
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK1/2/9 inhibitor
      insoluble in H2O; ≥18.55 mg/mL
  3. AZD8055
    A8214 AZD8055
     2 Citation
    Target: mTOR
    Summary: MTOR inhibitor
      ≥23.3 mg/mL
  4. Nedaplatin
    B1986 Nedaplatin
    Summary: DNA synthesis inhibitor
      insoluble in DMSO; insoluble in EtOH; ≥9.8 mg/mL
  5. Lapatinib Ditosylate
    A3967 Lapatinib Ditosylate
    Target: EGFR|ErbB-2
    Summary: EGFR/HER2 inhibitor,potent and selective
      ≥24.3 mg/mL
  6. AC480 (BMS-599626)
    A2822 AC480 (BMS-599626)
    Target: EGFR
    Summary: HER1/2 inhibitor,selective and efficacious
      ≥28.35 mg/mL
  7. Dacomitinib (PF299804, PF299)
    A8319 Dacomitinib (PF299804, PF299)
    Target: ErbB
    Summary: HER inhibitor
      ≥23.5 mg/mL
  8. CUDC-101
    A4092 CUDC-101
     1 Citation
    Target: Histone Deacetylases (HDACs)|EGFR|ErbB
    Summary: Multitargeted HDAC inhibitor
      ≥21.7 mg/mL
  9. AZD7762
    A5919 AZD7762
    Target: Chk
    Summary: Checkpoint kinase inhibitor,ATP competitive
      insoluble in H2O; insoluble in EtOH; ≥18.1 mg/mL
  10. Regorafenib
    A8236 Regorafenib
     4 Citation
    Target: Raf|VEGFR|PDGFR|c-Kit|RET
    Summary: Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1
      ≥25.04 mg/mL

Items 91-100 of 231

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Category
  1. Signaling Pathways 229item
  2. Natural Products 2item
Specificity
  1. Selective 183item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 18item
  2. Irreversible 6item
Target
  1. Cyclin-Dependent Kinases 22item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 5item
  4. PI3K 12item
  5. Raf 9item
  6. Aurora Kinases 16item
  7. CSF-1R 4item
  8. mTOR 6item
  9. AP-1 1 item
  10. FLT3 7item
  11. GSK-3 4item
  12. PLK 5item
  13. Chk 4item
  14. Eph Receptors 3item
  15. VEGFR 27item
  16. PDGFR 17item
  17. c-Kit 9item
  18. RET 4item
  19. Bromodomain-containing proteins(BRDs) 1 item
  20. Thymidylate Synthase 1 item
  21. p38 3item
  22. JNK 1 item
  23. SGK 2item
  24. Bcr-Abl 6item
  25. MEK 2item
  26. FGFR 9item
  27. Pim 3item
  28. Ribosomal s6 kinases (RSK) 1 item
  29. MET 5item
  30. Src 8item
  31. Trk Receptors 1 item
  32. STAT 4item
  33. EGFR 13item
  34. PAK 3item
  35. FAK 4item
  36. BMP and Other Activin Receptors 1 item
  37. JAK 8item
  38. Syk 3item
  39. DNA-PK 5item
  40. Topoisomerases 7item
  41. ErbB 4item
  42. DNA Methyltransferases 3item
  43. ERK 2item
  44. c-MET 5item
  45. PKC 8item
  46. Ubiquitin-specific proteases 1 item
  47. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  48. Lyn 1 item
  49. HER2 1 item
  50. Pyk2 3item
  51. Insulin and Insulin-like Receptors 2item
  52. ALK 5item
  53. ROS1 1 item
  54. Sphingosine kinases (SphKs) 1 item
  55. PKG 2item
  56. PKA 4item
  57. Myosin light chain kinases (MLCKs) 1 item
  58. MELK 1 item
  59. Insulin-like growth factors (IGFs) 1 item
  60. MK2 1 item
  61. Tie-2 1 item
  62. RSK 1 item
  63. ATM/ATR 3item
  64. CK1 1 item
  65. Farnesyl Diphosphate Synthases 1 item
  66. CK2 1 item
  67. HIPK2 1 item
  68. HIPK3 1 item
  69. BLM 1 item
  70. Synthases/Synthetases 1 item
  71. MAGL 1 item
  72. P110 1 item
  73. Hck 1 item
  74. RNA Polymerases 1 item
  75. MNK 1 item
  76. Insulin Receptors 1 item
  77. IRG-1R 1 item
  78. eEF-2 1 item
  79. Cdc7 1 item
  80. CMV 1 item
  81. ZAP-70 1 item
  82. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  83. Cytidine deaminases 1 item
  84. c-RET 2item
  85. p70 rsk 1 item
  86. VEGFR3/FLT4 1 item
  87. NTRK1/TRKA 1 item
  88. CSF-1R/c-Fms 1 item
  89. TAM kinase 1 item
  90. KDR 1 item
  91. AXL 1 item
  92. insulin 1 item
  93. ErbB-2 1 item
  94. PDK-1 1 item
  95. Prk 1 item
  96. Flk1 2item
  97. tropomyosin receptor kinase 1 item
  98. SK 1 item
  99. PPK 1 item
  100. c-Syk 1 item
  101. CDK1/CyclinB 1 item
  102. PIM1 kinase 1 item
  103. phospholipase A2 1 item
Reported Experiments
  1. Animal Experiments 217item
  2. Cell Experiments 146item