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  • Search results for: 'research area dna damage atm kinase'

Search results for: 'research area dna damage atm kinase'

Items 111-120 of 329

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  1. AC480 (BMS-599626)
    A2822 AC480 (BMS-599626)
    Target: EGFR
    Summary: HER1/2 inhibitor,selective and efficacious
      ≥28.35 mg/mL
  2. Dacomitinib (PF299804, PF299)
    A8319 Dacomitinib (PF299804, PF299)
    Target: ErbB
    Summary: HER inhibitor
      ≥23.5 mg/mL
  3. Neratinib (HKI-272)
    A8322 Neratinib (HKI-272)
     1 Citation
    Target: EGFR
    Summary: HER2/EGFR inhibitor,potent and irreversible
      insoluble in H2O; ≥13.93 mg/mL
  4. CUDC-101
    A4092 CUDC-101
     1 Citation
    Target: Histone Deacetylases (HDACs)|EGFR|ErbB
    Summary: Multitargeted HDAC inhibitor
      ≥21.7 mg/mL
  5. AZD7762
    A5919 AZD7762
    Target: Chk
    Summary: Checkpoint kinase inhibitor,ATP competitive
      insoluble in H2O; insoluble in EtOH; ≥18.1 mg/mL
  6. Regorafenib
    A8236 Regorafenib
     4 Citation
    Target: Raf|VEGFR|PDGFR|c-Kit|RET
    Summary: Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1
      ≥25.04 mg/mL
  7. Nintedanib (BIBF 1120)
    A8252 Nintedanib (BIBF 1120)
     3 Citation
    Target: VEGFR|PDGFR|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
  8. PD 173074
    A8253 PD 173074
    Target: VEGFR|FGFR
    Summary: FGFR inhibitor
      ≥26.18 mg/mL
  9. PHA-793887
    A5459 PHA-793887
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Pan-Cdk inhibitor
      insoluble in H2O; ≥18.05 mg/mL
  10. Palbociclib (PD0332991) Isethionate
    A8335 Palbociclib (PD0332991) Isethionate
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥28.7 mg/mL

Items 111-120 of 329

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Category
  1. Signaling Pathways 323item
  2. Natural Products 3item
  3. Lab Reagents 2item
Specificity
  1. Selective 242item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 22item
  2. Irreversible 6item
Target
  1. Cyclin-Dependent Kinases 22item
  2. Histone Deacetylases (HDACs) 1 item
  3. Akt 5item
  4. PI3K 16item
  5. Raf 10item
  6. Aurora Kinases 18item
  7. CSF-1R 4item
  8. mTOR 9item
  9. AP-1 1 item
  10. FLT3 13item
  11. GSK-3 8item
  12. PLK 6item
  13. Chk 5item
  14. Eph Receptors 2item
  15. VEGFR 30item
  16. PDGFR 22item
  17. c-Kit 12item
  18. RET 4item
  19. IRAK 1 item
  20. Bromodomain-containing proteins(BRDs) 1 item
  21. Thymidylate Synthase 1 item
  22. p38 6item
  23. PKB 1 item
  24. JNK 1 item
  25. SGK 1 item
  26. Bcr-Abl 11item
  27. MEK 3item
  28. FGFR 12item
  29. Pim 3item
  30. Voltage-gated Sodium (NaV) Channels 1 item
  31. MET 5item
  32. Src 14item
  33. Trk Receptors 2item
  34. STAT 6item
  35. Estrogen and Related Receptors 1 item
  36. EGFR 16item
  37. Reverse Transcriptases 1 item
  38. ROCK 5item
  39. BTK 1 item
  40. PAK 3item
  41. FAK 4item
  42. BMP and Other Activin Receptors 2item
  43. JAK 14item
  44. Syk 5item
  45. DNA-PK 7item
  46. AMPK 2item
  47. PDHK 1 item
  48. Topoisomerases 9item
  49. Cytochrome P450 (CYP450) 1 item
  50. ErbB 4item
  51. S6 kinases 1 item
  52. Adenosine Kinases 2item
  53. DNA Methyltransferases 2item
  54. ERK 4item
  55. c-MET 5item
  56. PKC 11item
  57. Ubiquitin-specific proteases 1 item
  58. Ca2 /calmodulin-dependent protein kinases (CaMKs) 5item
  59. Lyn 2item
  60. HER2 2item
  61. Pyk2 3item
  62. LRRK2 5item
  63. Insulin and Insulin-like Receptors 3item
  64. ALK 6item
  65. ROS1 1 item
  66. Sphingosine kinases (SphKs) 2item
  67. PKG 1 item
  68. PKA 4item
  69. Myosin light chain kinases (MLCKs) 1 item
  70. MELK 1 item
  71. Insulin-like growth factors (IGFs) 1 item
  72. MK2 2item
  73. Fatty-acid-binding proteins (FABPs) 1 item
  74. Angiotensin-Converting Enzymes (ACEs) 1 item
  75. Tie-2 2item
  76. RSK 2item
  77. phosphatases 1 item
  78. ATM/ATR 3item
  79. Farnesyl Diphosphate Synthases 1 item
  80. CK2 2item
  81. HIPK2 1 item
  82. HIPK3 1 item
  83. HIV Integrases 1 item
  84. P2X Receptors 1 item
  85. BLM 1 item
  86. HSV 1 item
  87. Synthases/Synthetases 2item
  88. MAGL 1 item
  89. Histamine H1 Receptors 1 item
  90. P110 1 item
  91. Hck 2item
  92. RNA Polymerases 2item
  93. MNK 1 item
  94. 5-Lipoxygenases 1 item
  95. Insulin Receptors 1 item
  96. IRG-1R 1 item
  97. Cdc2-like kinase (Clk) 1 item
  98. eEF-2 1 item
  99. Cdc7 1 item
  100. CMV 1 item
  101. ZAP-70 1 item
  102. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  103. Cytidine deaminases 1 item
  104. c-RET 3item
  105. p70 rsk 2item
  106. VEGFR3/FLT4 1 item
  107. NTRK1/TRKA 1 item
  108. CSF-1R/c-Fms 1 item
  109. TAM kinase 1 item
  110. KDR 1 item
  111. Fyn kinase 1 item
  112. AXL 1 item
  113. c-Fms tyrosine kinase 1 item
  114. insulin 1 item
  115. PPAR 1 item
  116. MSK 1 item
  117. Lyn kinase 1 item
  118. Mer tyrosine kinase 1 item
  119. ErbB-2 1 item
  120. PDK-1 1 item
  121. Histone Acetyltransferases (HATs) 1 item
  122. Prk 1 item
  123. ITK 1 item
  124. NUAK 1 item
  125. DCLK2 1 item
  126. PTK 2item
  127. phosphatidylinositol kinase 1 item
  128. prolactin secretion 1 item
  129. gonadotropin release 1 item
  130. Flk1 2item
  131. glutamate release 1 item
  132. FGR 1 item
  133. YES 2item
  134. Fyn 2item
  135. ARG 1 item
  136. TRPC channel 1 item
  137. PKD 1 item
  138. Pyruvate kinases 1 item
  139. enoyl-acyl-carrier protein reductase 1 item
  140. Rho-kinase 1 item
  141. tropomyosin receptor kinase 1 item
  142. SK 1 item
  143. PPK 1 item
  144. c-Syk 1 item
  145. CDK1/CyclinB 1 item
  146. PIM1 kinase 1 item
  147. phospholipase A2 1 item
  148. ATM 1 item
  149. Sirtuin 1 item
  150. PIKfyve 1 item
  151. Insulin Receptor 1 item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 15item
  3. Acute Renal Failure 1 item
  4. Adrenocortical Carcinoma 2item
  5. Advanced Renal Cell Carcinoma 1 item
  6. Bladder Cancer 5item
  7. Bladder Carcinoma 2item
  8. Bladder Diseases 1 item
  9. B-lymphoid Malignancies 1 item
  10. Breast Cancer 48item
  11. Cancer 217item
  12. Cervical Cancer 5item
  13. Cholangiocarcinoma 2item
  14. Chronic Lymphocytic Leukemia 2item
  15. Clear Cell Renal Cell Carcinoma 1 item
  16. Colon Cancer 21item
  17. Colon Carcinoma 2item
  18. Colorectal Cancer 21item
  19. Glioblastoma 18item
  20. Glioma 6item
  21. Hepatocellular Carcinoma 5item
  22. HIV 1 item
  23. HIV Infections 2item
  24. Immunological Diseases 1 item
  25. Inflammatory Bowel Disease 1 item
  26. Inflammatory Diseases 4item
  27. Leukemia 13item
  28. Liver Cancer 3item
  29. Lung Cancer 16item
  30. Lung Carcinoma 3item
  31. Lymphoma 12item
  32. Mantle Cell Lymphoma 1 item
  33. Melanoma 15item
  34. Multiple Myeloma 5item
  35. Myelofibrosis 1 item
  36. Myeloma 2item
  37. Neuroblastoma 3item
  38. Non-small Cell Lung Cancer 5item
  39. Non-small Cell Lung Carcinoma 1 item
  40. Ovarian Cancer 19item
  41. Pancreatic Cancer 24item
  42. Prostate Cancer 18item
  43. Psoriasis 1 item
  44. Pulmonary Arterial Hypertension 1 item
  45. Renal Cancer 3item
  46. Renal Cell Carcinoma 5item
  47. Rheumatoid Arthritis 5item
  48. Sarcoma 1 item
  49. Squamous Cell Carcinoma 1 item
  50. Testicular Cancer 2item
  51. Thyroid Cancer 5item
  52. Type 2 Diabetes 3item