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  • Search results for: 'research area epigenetics hypoxia inducible factors'

Search results for: 'research area epigenetics hypoxia inducible factors'

Items 11-20 of 113

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  1. AR-42 (OSU-HDAC42)
    A4104 AR-42 (OSU-HDAC42)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,novel and potent
      insoluble in EtOH; insoluble in H2O; ≥15.62 mg/mL
  2. Veliparib dihydrochloride
    A3958 Veliparib dihydrochloride
    Target: PARP
    Summary: PARP-1/PARP-2 inhibitor
      ≥31.7 mg/mL
  3. AZD1208
    A3962 AZD1208
    Target: Pim
    Summary: PIM kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.95 mg/mL
  4. Tenovin-6
    A8302 Tenovin-6
    Target: Sir2-like Family Deacetylases (Sirtuins)
    Summary: SIRT inhibitor and p53 activator
      ≥22.75 mg/mL
  5. Ruxolitinib (INCB018424)
    A3012 Ruxolitinib (INCB018424)
     4 Citation
    Target: JAK
    Summary: JAK inhibitor
      insoluble in H2O; ≥15.32 mg/mL
  6. LY2784544
    A4147 LY2784544
    Target: Aurora Kinases|FLT3|VEGFR|FGFR|Trk Receptors|JAK|ALK|TYK2|MUSK|MAP3K
    Summary: JAK2 inhibitor,highly potent and selective
      ≥23.5 mg/mL
  7. Pracinostat (SB939)
    A4095 Pracinostat (SB939)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Pan-HDAC inhibitor
      insoluble in H2O; ≥11.4 mg/mL
  8. Belinostat (PXD101)
    A4096 Belinostat (PXD101)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Hydroxamate-type HDAC inhibitor
      insoluble in H2O; ≥15.92 mg/mL
  9. TH-302
    A3872 TH-302
    Summary: Hypoxia-activated prodrug,inhibits H460/HT29 cell growth
      ≥22.45 mg/mL
  10. NSC 687852 (b-AP15)
    A4453 NSC 687852 (b-AP15)
    Target: Deubiquitinating enzymes (DUBs)
    Summary: 19S regulatory particle Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥20.95 mg/mL

Items 11-20 of 113

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Category
  1. Proteases 4item
  2. Apoptosis 14item
  3. Chromatin/Epigenetics 51item
  4. Metabolism 3item
  5. MAPK Signaling 3item
  6. Tyrosine Kinase 26item
  7. DNA Damage/DNA Repair 23item
  8. PI3K/Akt/mTOR Signaling 1 item
  9. Cell Cycle/Checkpoint 15item
  10. Ubiquitination/ Proteasome 3item
  11. JAK/STAT Signaling 16item
  12. TGF-β / Smad Signaling 2item
  13. Angiogenesis 3item
  14. GPCR/G protein 1 item
  15. Stem Cell 4item
  16. Others 4item
  17. Immunology/Inflammation 1 item
Specificity
  1. Selective 86item
Reversibility
  1. Reversible 2item
  2. Irreversible 4item
Target
  1. Caspases 2item
  2. Histone Deacetylases (HDACs) 15item
  3. Bcl-2 1 item
  4. PI3K 1 item
  5. Raf 2item
  6. Aurora Kinases 13item
  7. Bcl-xl 1 item
  8. CSF-1R 3item
  9. EZH2 2item
  10. Bromodomains 2item
  11. AP-1 1 item
  12. DT-diaphorases 1 item
  13. FLT3 4item
  14. LPA Receptors 1 item
  15. PLK 2item
  16. VEGFR 12item
  17. PDGFR 8item
  18. c-Kit 4item
  19. RET 1 item
  20. Bromodomain-containing proteins(BRDs) 1 item
  21. Mcl-1 1 item
  22. SGK 1 item
  23. DOT1L 1 item
  24. FGFR 7item
  25. Insulin-like growth factor receptors(IGFRs) 1 item
  26. Pim 2item
  27. Liver X receptors (LXRs) 1 item
  28. Sir2-like Family Deacetylases (Sirtuins) 1 item
  29. Deubiquitinating enzymes (DUBs) 1 item
  30. PP1 1 item
  31. PP2A 1 item
  32. Smoothened 1 item
  33. MET 1 item
  34. Src 1 item
  35. Trk Receptors 1 item
  36. STAT 2item
  37. EGFR 7item
  38. Hypoxia Inducible Factors (HIFs) 1 item
  39. JAK 5item
  40. DNA-PK 1 item
  41. HSP90 1 item
  42. Topoisomerases 1 item
  43. ErbB 3item
  44. Actin 1 item
  45. DNA Methyltransferases 3item
  46. ERK 1 item
  47. PKC 1 item
  48. CREBBP 1 item
  49. EP300 1 item
  50. Lyn 1 item
  51. HER2 1 item
  52. Insulin and Insulin-like Receptors 1 item
  53. PARP 1 item
  54. ALK 1 item
  55. Dehydrogenase 1 item
  56. Autophagy 2item
  57. Farnesyl Diphosphate Synthases 1 item
  58. MAGL 1 item
  59. Apoptosis Inducers 1 item
  60. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  61. Cytidine deaminases 1 item
  62. PP4 1 item
  63. VEGFR3/FLT4 1 item
  64. NTRK1/TRKA 1 item
  65. CSF-1R/c-Fms 1 item
  66. p53 2item
  67. HDAC 1 item
  68. insulin 1 item
  69. HDM2 ubiquitin ligase 1 item
  70. GLI 1 item
  71. Trx 1 item
  72. TYK2 1 item
  73. MUSK 1 item
  74. MAP3K 1 item
  75. RHA 1 item
Reported Experiments
  1. Animal Experiments 104item
  2. Cell Experiments 69item