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  • Search results for: 'research area epigenetics hypoxia inducible factors'

Search results for: 'research area epigenetics hypoxia inducible factors'

Items 11-20 of 131

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  1. Mocetinostat (MGCD0103, MG0103)
    A4089 Mocetinostat (MGCD0103, MG0103)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,isotype-selective and potent
      insoluble in EtOH; insoluble in H2O; ≥19.8 mg/mL
  2. EPZ5676
    A4166 EPZ5676
     1 Citation
    Target: DOT1L
    Summary: DOT1L inhibitor,potent and SAM competitive
      ≥28.15 mg/mL
  3. AR-42 (OSU-HDAC42)
    A4104 AR-42 (OSU-HDAC42)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,novel and potent
      insoluble in EtOH; insoluble in H2O; ≥15.62 mg/mL
  4. AZD1208
    A3962 AZD1208
    Target: Pim
    Summary: PIM kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.95 mg/mL
  5. Tubacin
    A4501 Tubacin
     3 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC6 inhibitor,potent,selective,reversible,cell-permeable
      insoluble in EtOH; insoluble in H2O; ≥7.19 mg/mL
  6. SGC-CBP30
    A4491 SGC-CBP30
     2 Citation
    Target: CREBBP|EP300
    Summary: Inhibitor of CREBBP/EP300 bromodomain,potent
      ≥20.05 mg/mL
  7. Tenovin-6
    A8302 Tenovin-6
    Target: Sir2-like Family Deacetylases (Sirtuins)
    Summary: SIRT inhibitor and p53 activator
      ≥22.75 mg/mL
  8. SRT2104 (GSK2245840)
    A3821 SRT2104 (GSK2245840)
     1 Citation
    Target: Sir2-like Family Deacetylases (Sirtuins)
    Summary: SIRT1 activator,selective
      insoluble in H2O; insoluble in EtOH; ≥6.46 mg/mL
  9. Ruxolitinib (INCB018424)
    A3012 Ruxolitinib (INCB018424)
     4 Citation
    Target: JAK
    Summary: JAK inhibitor
      insoluble in H2O; ≥15.32 mg/mL
  10. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL

Items 11-20 of 131

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Category
  1. Proteases 8item
  2. Apoptosis 13item
  3. Chromatin/Epigenetics 58item
  4. Metabolism 5item
  5. MAPK Signaling 2item
  6. Tyrosine Kinase 25item
  7. DNA Damage/DNA Repair 25item
  8. PI3K/Akt/mTOR Signaling 1 item
  9. Cell Cycle/Checkpoint 13item
  10. Ubiquitination/ Proteasome 5item
  11. JAK/STAT Signaling 14item
  12. TGF-β / Smad Signaling 3item
  13. Angiogenesis 3item
  14. GPCR/G protein 2item
  15. Stem Cell 4item
  16. Membrane Transporter/Ion Channel 1 item
  17. Others 5item
  18. Immunology/Inflammation 3item
Reversibility
  1. Reversible 6item
  2. Irreversible 2item
Target
  1. Caspases 2item
  2. Cyclin-Dependent Kinases 1 item
  3. Proteasome 1 item
  4. Histone Deacetylases (HDACs) 17item
  5. Bcl-2 1 item
  6. PI3K 1 item
  7. Raf 1 item
  8. Aurora Kinases 10item
  9. Bcl-xl 1 item
  10. CSF-1R 1 item
  11. EZH2 2item
  12. Bromodomains 1 item
  13. AP-1 2item
  14. MMP 2item
  15. DT-diaphorases 1 item
  16. FLT3 1 item
  17. Factor Xa 3item
  18. LPA Receptors 1 item
  19. PLK 1 item
  20. VEGFR 8item
  21. PDGFR 5item
  22. c-Kit 2item
  23. Bromodomain-containing proteins(BRDs) 1 item
  24. Mcl-1 1 item
  25. Hydrolase 1 item
  26. SGK 1 item
  27. MEK 1 item
  28. DOT1L 1 item
  29. FGFR 3item
  30. Nrf2 1 item
  31. Insulin-like growth factor receptors(IGFRs) 1 item
  32. Pim 2item
  33. Sir2-like Family Deacetylases (Sirtuins) 3item
  34. Deubiquitinating enzymes (DUBs) 1 item
  35. PP1 1 item
  36. PP2A 1 item
  37. Smoothened 1 item
  38. MET 1 item
  39. Src 1 item
  40. STAT 1 item
  41. EGFR 5item
  42. RIP kinases 1 item
  43. Hypoxia Inducible Factors (HIFs) 1 item
  44. JAK 4item
  45. DNA-PK 1 item
  46. HSP90 1 item
  47. Topoisomerases 1 item
  48. ErbB 2item
  49. Ferroptosis 1 item
  50. Toll-like receptors (TLRs) 1 item
  51. Actin 1 item
  52. DNA Methyltransferases 3item
  53. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  54. ERK 1 item
  55. CREBBP 2item
  56. EP300 2item
  57. Lyn 1 item
  58. HER2 1 item
  59. Insulin and Insulin-like Receptors 2item
  60. PARP 1 item
  61. Dehydrogenase 1 item
  62. Pancreatic and duodenal homeobox 1 (PDX1) 1 item
  63. Fatty-acid-binding proteins (FABPs) 1 item
  64. Free Fatty Acid Receptors 1 item
  65. phosphatases 1 item
  66. Autophagy 2item
  67. C5a receptors 1 item
  68. Farnesyl Diphosphate Synthases 1 item
  69. G9a 1 item
  70. MAGL 1 item
  71. TRP Channel 2item
  72. Apoptosis Inducers 1 item
  73. NO Donors / Precursors 1 item
  74. IL Receptors 1 item
  75. 15-lipoxygenases 1 item
  76. Arp2/3 complex 1 item
  77. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  78. Cytidine deaminases 1 item
  79. PP4 1 item
  80. c-RET 1 item
  81. c-Fms tyrosine kinase 1 item
  82. Elastases 1 item
  83. P97 ATPase 1 item
  84. Histone Acetyltransferases (HATs) 1 item
  85. Lck 1 item
  86. Sirtuin 1 item
Reported Experiments
  1. Animal Experiments 113item
  2. Cell Experiments 72item
Related Disease
  1. Acute Lung Injury 1 item
  2. Acute Myeloid Leukemia 8item
  3. Adrenocortical Carcinoma 1 item
  4. Bladder Cancer 4item
  5. Bladder Carcinoma 1 item
  6. Breast Cancer 29item
  7. Cancer 86item
  8. Cervical Cancer 2item
  9. Chronic Lymphocytic Leukemia 1 item
  10. Chronic Myeloproliferative Disorders 1 item
  11. Colon Cancer 12item
  12. Colon Carcinoma 1 item
  13. Colorectal Cancer 10item
  14. Diabetes 2item
  15. Glioblastoma 8item
  16. Glioma 2item
  17. Hepatic Cancer 1 item
  18. Hepatocellular Carcinoma 1 item
  19. HIV Infections 1 item
  20. Inflammatory Diseases 2item
  21. Leukemia 3item
  22. Liver Cancer 2item
  23. Lung Cancer 9item
  24. Lung Carcinoma 1 item
  25. Lymphoma 6item
  26. Melanoma 5item
  27. Mixed Lineage Leukemia 1 item
  28. Multiple Myeloma 7item
  29. Myelofibrosis 2item
  30. Myeloma 2item
  31. Neuroblastoma 1 item
  32. Neuronal Protection 1 item
  33. Non-small Cell Lung Cancer 7item
  34. Ovarian Cancer 10item
  35. Pain Relief 1 item
  36. Pancreatic Cancer 11item
  37. Prostate Cancer 18item
  38. Psoriasis 1 item
  39. Pulmonary Arterial Hypertension 1 item
  40. Pulmonary Fibrosis 1 item
  41. Renal Cancer 1 item
  42. Renal Cell Carcinoma 5item
  43. Rheumatoid Arthritis 2item
  44. Soft Tissue Sarcoma 1 item
  45. Testicular Cancer 1 item
  46. Thyroid Cancer 2item
  47. Type 2 Diabetes 3item