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  • Search results for: 'research area epigenetics hypoxia inducible factors'

Search results for: 'research area epigenetics hypoxia inducible factors'

Items 71-80 of 113

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  1. Sunitinib malate
    A8255 Sunitinib malate
     2 Citation
    Target: VEGFR
    Summary: VEGFR/PDGFRβ/ KIT/ FLT3/RET/CSF-1R inhibitor
      ≥26.65 mg/mL
  2. BAY 87-2243
    B1115 BAY 87-2243
    Target: Hypoxia Inducible Factors (HIFs)
    Summary: HIF-1 inhibitor,potent and selective
  3. GANT61
    A1615 GANT61
     1 Citation
    Target: GLI
    Summary: GLI antagonist
  4. Pomalidomide (CC-4047)
    A4212 Pomalidomide (CC-4047)
    Summary: Immunomodulator,antumor/anti-angiogenic
      insoluble in EtOH; insoluble in H2O; ≥7.5 mg/mL
  5. Pazopanib (GW-786034)
    A3022 Pazopanib (GW-786034)
    Target: CSF-1R|VEGFR|PDGFR|c-Kit|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥10.95 mg/mL
  6. MLN0905
    A8680 MLN0905
    Target: PLK
    Summary: Potent PLK1 inhibitor
      ≥24.35 mg/mL
  7. JNJ-26854165 (Serdemetan)
    A4204 JNJ-26854165 (Serdemetan)
     1 Citation
    Target: p53|HDM2 ubiquitin ligase
    Summary: P53 activator, blocking Mdm2-p53 interaction
      insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
  8. Chidamide
    B5916 Chidamide
     1 Citation
    Target: HDAC
    Summary: Novel HDAC inhibitor
      insoluble in H2O; insoluble in EtOH; ≥18.55 mg/mL
  9. Afatinib (BIBW2992)
    A8247 Afatinib (BIBW2992)
     1 Citation
    Target: EGFR
    Summary: Irreversible EGFR/HER2 inhibitor
      ≥24.3 mg/mL
  10. Sorafenib
    A3009 Sorafenib
     2 Citation
    Target: Raf|VEGFR
    Summary: Raf kinases and tyrosine kinases inhibitor
      ≥23.25 mg/mL

Items 71-80 of 113

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Category
  1. Proteases 4item
  2. Apoptosis 14item
  3. Chromatin/Epigenetics 51item
  4. Metabolism 3item
  5. MAPK Signaling 3item
  6. Tyrosine Kinase 26item
  7. DNA Damage/DNA Repair 23item
  8. PI3K/Akt/mTOR Signaling 1 item
  9. Cell Cycle/Checkpoint 15item
  10. Ubiquitination/ Proteasome 3item
  11. JAK/STAT Signaling 16item
  12. TGF-β / Smad Signaling 2item
  13. Angiogenesis 3item
  14. GPCR/G protein 1 item
  15. Stem Cell 4item
  16. Others 4item
  17. Immunology/Inflammation 1 item
Specificity
  1. Selective 86item
Reversibility
  1. Reversible 2item
  2. Irreversible 4item
Target
  1. Caspases 2item
  2. Histone Deacetylases (HDACs) 15item
  3. Bcl-2 1 item
  4. PI3K 1 item
  5. Raf 2item
  6. Aurora Kinases 13item
  7. Bcl-xl 1 item
  8. CSF-1R 3item
  9. EZH2 2item
  10. Bromodomains 2item
  11. AP-1 1 item
  12. DT-diaphorases 1 item
  13. FLT3 4item
  14. LPA Receptors 1 item
  15. PLK 2item
  16. VEGFR 12item
  17. PDGFR 8item
  18. c-Kit 4item
  19. RET 1 item
  20. Bromodomain-containing proteins(BRDs) 1 item
  21. Mcl-1 1 item
  22. SGK 1 item
  23. DOT1L 1 item
  24. FGFR 7item
  25. Insulin-like growth factor receptors(IGFRs) 1 item
  26. Pim 2item
  27. Liver X receptors (LXRs) 1 item
  28. Sir2-like Family Deacetylases (Sirtuins) 1 item
  29. Deubiquitinating enzymes (DUBs) 1 item
  30. PP1 1 item
  31. PP2A 1 item
  32. Smoothened 1 item
  33. MET 1 item
  34. Src 1 item
  35. Trk Receptors 1 item
  36. STAT 2item
  37. EGFR 7item
  38. Hypoxia Inducible Factors (HIFs) 1 item
  39. JAK 5item
  40. DNA-PK 1 item
  41. HSP90 1 item
  42. Topoisomerases 1 item
  43. ErbB 3item
  44. Actin 1 item
  45. DNA Methyltransferases 3item
  46. ERK 1 item
  47. PKC 1 item
  48. CREBBP 1 item
  49. EP300 1 item
  50. Lyn 1 item
  51. HER2 1 item
  52. Insulin and Insulin-like Receptors 1 item
  53. PARP 1 item
  54. ALK 1 item
  55. Dehydrogenase 1 item
  56. Autophagy 2item
  57. Farnesyl Diphosphate Synthases 1 item
  58. MAGL 1 item
  59. Apoptosis Inducers 1 item
  60. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  61. Cytidine deaminases 1 item
  62. PP4 1 item
  63. VEGFR3/FLT4 1 item
  64. NTRK1/TRKA 1 item
  65. CSF-1R/c-Fms 1 item
  66. p53 2item
  67. HDAC 1 item
  68. insulin 1 item
  69. HDM2 ubiquitin ligase 1 item
  70. GLI 1 item
  71. Trx 1 item
  72. TYK2 1 item
  73. MUSK 1 item
  74. MAP3K 1 item
  75. RHA 1 item
Reported Experiments
  1. Animal Experiments 104item
  2. Cell Experiments 69item