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  • Search results for: 'research area epigenetics hypoxia inducible factors'

Search results for: 'research area epigenetics hypoxia inducible factors'

Items 1-10 of 113

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  1. PX 12
    A4509 PX 12
    Target: Trx
    Summary: Trx-1 inhibitor
      insoluble in H2O; ≥8.75 mg/mL
  2. Apicidin
    A8176 Apicidin
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Potent HDAC inhibitor
      soluble in DMSO or ethanol
  3. Vorinostat (SAHA, MK0683)
    A4084 Vorinostat (SAHA, MK0683)
     9 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in EtOH; insoluble in H2O; ≥4.41 mg/mL
  4. Matrine
    A3583 Matrine
    Summary: Alkaloid found in Sophora plant
      ≥12.42 mg/mL
  5. AZD1480
    A4137 AZD1480
    Target: JAK
    Summary: JAK2 inhibitor,ATP-competitive and novel
      insoluble in H2O; ≥93.8 mg/mL
  6. 2,3-DCPE hydrochloride
    A4447 2,3-DCPE hydrochloride
    Target: Apoptosis Inducers
    Summary: Bcl-XL protein expression downregulator
      <30.06 mg/mL
  7. Actinomycin D
    A4448 Actinomycin D
     15 Citation
    Summary: RNA polymerase inhibitor
      ≥62.75 mg/mL
  8. M344
    A4105 M344
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,potent and cell-permeable
  9. Mocetinostat (MGCD0103, MG0103)
    A4089 Mocetinostat (MGCD0103, MG0103)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,isotype-selective and potent
      insoluble in EtOH; insoluble in H2O; ≥19.8 mg/mL
  10. EPZ5676
    A4166 EPZ5676
     1 Citation
    Target: DOT1L
    Summary: DOT1L inhibitor,potent and SAM competitive
      ≥28.15 mg/mL

Items 1-10 of 113

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Category
  1. Proteases 4item
  2. Apoptosis 14item
  3. Chromatin/Epigenetics 51item
  4. Metabolism 3item
  5. MAPK Signaling 3item
  6. Tyrosine Kinase 26item
  7. DNA Damage/DNA Repair 23item
  8. PI3K/Akt/mTOR Signaling 1 item
  9. Cell Cycle/Checkpoint 15item
  10. Ubiquitination/ Proteasome 3item
  11. JAK/STAT Signaling 16item
  12. TGF-β / Smad Signaling 2item
  13. Angiogenesis 3item
  14. GPCR/G protein 1 item
  15. Stem Cell 4item
  16. Others 4item
  17. Immunology/Inflammation 1 item
Specificity
  1. Selective 86item
Reversibility
  1. Reversible 2item
  2. Irreversible 4item
Target
  1. Caspases 2item
  2. Histone Deacetylases (HDACs) 15item
  3. Bcl-2 1 item
  4. PI3K 1 item
  5. Raf 2item
  6. Aurora Kinases 13item
  7. Bcl-xl 1 item
  8. CSF-1R 3item
  9. EZH2 2item
  10. Bromodomains 2item
  11. AP-1 1 item
  12. DT-diaphorases 1 item
  13. FLT3 4item
  14. LPA Receptors 1 item
  15. PLK 2item
  16. VEGFR 12item
  17. PDGFR 8item
  18. c-Kit 4item
  19. RET 1 item
  20. Bromodomain-containing proteins(BRDs) 1 item
  21. Mcl-1 1 item
  22. SGK 1 item
  23. DOT1L 1 item
  24. FGFR 7item
  25. Insulin-like growth factor receptors(IGFRs) 1 item
  26. Pim 2item
  27. Liver X receptors (LXRs) 1 item
  28. Sir2-like Family Deacetylases (Sirtuins) 1 item
  29. Deubiquitinating enzymes (DUBs) 1 item
  30. PP1 1 item
  31. PP2A 1 item
  32. Smoothened 1 item
  33. MET 1 item
  34. Src 1 item
  35. Trk Receptors 1 item
  36. STAT 2item
  37. EGFR 7item
  38. Hypoxia Inducible Factors (HIFs) 1 item
  39. JAK 5item
  40. DNA-PK 1 item
  41. HSP90 1 item
  42. Topoisomerases 1 item
  43. ErbB 3item
  44. Actin 1 item
  45. DNA Methyltransferases 3item
  46. ERK 1 item
  47. PKC 1 item
  48. CREBBP 1 item
  49. EP300 1 item
  50. Lyn 1 item
  51. HER2 1 item
  52. Insulin and Insulin-like Receptors 1 item
  53. PARP 1 item
  54. ALK 1 item
  55. Dehydrogenase 1 item
  56. Autophagy 2item
  57. Farnesyl Diphosphate Synthases 1 item
  58. MAGL 1 item
  59. Apoptosis Inducers 1 item
  60. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  61. Cytidine deaminases 1 item
  62. PP4 1 item
  63. VEGFR3/FLT4 1 item
  64. NTRK1/TRKA 1 item
  65. CSF-1R/c-Fms 1 item
  66. p53 2item
  67. HDAC 1 item
  68. insulin 1 item
  69. HDM2 ubiquitin ligase 1 item
  70. GLI 1 item
  71. Trx 1 item
  72. TYK2 1 item
  73. MUSK 1 item
  74. MAP3K 1 item
  75. RHA 1 item
Reported Experiments
  1. Animal Experiments 104item
  2. Cell Experiments 69item