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Search results for: 'research area epigenetics hypoxia inducible factors'

Search results for: 'research area epigenetics hypoxia inducible factors'

A8176 Apicidin

2 Citation

Target: Histone Deacetylases (HDACs)

Summary: Potent HDAC inhibitor

soluble in DMSO or ethanol
A4084 Vorinostat (SAHA, MK0683)

9 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.41 mg/mL
A4105 M344

1 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor,potent and cell-permeable
A4089 Mocetinostat (MGCD0103, MG0103)

2 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor,isotype-selective and potent

insoluble in EtOH; insoluble in H2O; ≥19.8 mg/mL
A4104 AR-42 (OSU-HDAC42)

2 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor,novel and potent

insoluble in EtOH; insoluble in H2O; ≥15.62 mg/mL
A3958 Veliparib dihydrochloride

Target: PARP

Summary: PARP-1/PARP-2 inhibitor

≥31.7 mg/mL
A4095 Pracinostat (SB939)

2 Citation

Target: Histone Deacetylases (HDACs)

Summary: Pan-HDAC inhibitor

insoluble in H2O; ≥11.4 mg/mL
A4096 Belinostat (PXD101)

2 Citation

Target: Histone Deacetylases (HDACs)

Summary: Hydroxamate-type HDAC inhibitor

insoluble in H2O; ≥15.92 mg/mL
A3872 TH-302

Summary: Hypoxia-activated prodrug,inhibits H460/HT29 cell growth

≥22.45 mg/mL
A1912 Lomeguatrib

Target: O6-methylguanine-DNA-methyl-transferase (MGMT)

Summary: MGMT inhibitor

≥50 mg/mL