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Search results for: 'research area epigenetics hypoxia inducible factors'

Search results for: 'research area epigenetics hypoxia inducible factors'

A8176 Apicidin

2 Citation

Target: Histone Deacetylases (HDACs)

Summary: Potent HDAC inhibitor

soluble in DMSO or ethanol
A4084 Vorinostat (SAHA, MK0683)

9 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.41 mg/mL
A4105 M344

1 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor,potent and cell-permeable
A4089 Mocetinostat (MGCD0103, MG0103)

2 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor,isotype-selective and potent

insoluble in EtOH; insoluble in H2O; ≥19.8 mg/mL
A4166 EPZ5676

1 Citation

Target: DOT1L

Summary: DOT1L inhibitor,potent and SAM competitive

≥28.15 mg/mL
A4104 AR-42 (OSU-HDAC42)

2 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor,novel and potent

insoluble in EtOH; insoluble in H2O; ≥15.62 mg/mL
A3962 AZD1208

Target: Pim

Summary: PIM kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥18.95 mg/mL
A8302 Tenovin-6

Target: Sir2-like Family Deacetylases (Sirtuins)

Summary: SIRT inhibitor and p53 activator

≥22.75 mg/mL
A3012 Ruxolitinib (INCB018424)

4 Citation

Target: JAK

Summary: JAK inhibitor

insoluble in H2O; ≥15.32 mg/mL
A4096 Belinostat (PXD101)

2 Citation

Target: Histone Deacetylases (HDACs)

Summary: Hydroxamate-type HDAC inhibitor

insoluble in H2O; ≥15.92 mg/mL