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  • Search results for: 'research area epigenetics hypoxia inducible factors'

Search results for: 'research area epigenetics hypoxia inducible factors'

Items 1-10 of 56

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  1. PX 12
    A4509 PX 12
    Target: Trx
    Summary: Trx-1 inhibitor
      insoluble in H2O; ≥8.75 mg/mL
  2. Vorinostat (SAHA, MK0683)
    A4084 Vorinostat (SAHA, MK0683)
     9 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in EtOH; insoluble in H2O; ≥4.41 mg/mL
  3. AZD1480
    A4137 AZD1480
    Target: JAK
    Summary: JAK2 inhibitor,ATP-competitive and novel
      insoluble in H2O; ≥93.8 mg/mL
  4. Mocetinostat (MGCD0103, MG0103)
    A4089 Mocetinostat (MGCD0103, MG0103)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,isotype-selective and potent
      insoluble in EtOH; insoluble in H2O; ≥19.8 mg/mL
  5. Veliparib dihydrochloride
    A3958 Veliparib dihydrochloride
    Target: PARP
    Summary: PARP-1/PARP-2 inhibitor
      ≥31.7 mg/mL
  6. AZD1208
    A3962 AZD1208
    Target: Pim
    Summary: PIM kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.95 mg/mL
  7. Tubacin
    A4501 Tubacin
     3 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC6 inhibitor,potent,selective,reversible,cell-permeable
      insoluble in EtOH; insoluble in H2O; ≥7.19 mg/mL
  8. Ruxolitinib (INCB018424)
    A3012 Ruxolitinib (INCB018424)
     4 Citation
    Target: JAK
    Summary: JAK inhibitor
      insoluble in H2O; ≥15.32 mg/mL
  9. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL
  10. LY2784544
    A4147 LY2784544
    Target: Aurora Kinases|FLT3|VEGFR|FGFR|Trk Receptors|JAK|ALK|TYK2|MUSK|MAP3K
    Summary: JAK2 inhibitor,highly potent and selective
      ≥23.5 mg/mL

Items 1-10 of 56

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  1. Category Chromatin/Epigenetics Remove This Item
  2. Reported Experiments Cell Experiments Remove This Item
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Category
  1. Bromodomain 2item
  2. Aurora Kinase 12item
  3. DNA Methyltransferase 2item
  4. HDAC 16item
  5. Histone Acetyltransferases 1 item
  6. Histone Methyltransferase 3item
  7. HIF 2item
  8. JAK 9item
  9. PARP 2item
  10. Pim 1 item
  11. Protein Ser/Thr Phosphatases 3item
  12. Sirtuin 3item
Specificity
  1. Selective 36item
Reversibility
  1. Reversible 2item
  2. Irreversible 1 item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 15item
  3. Aurora Kinases 13item
  4. EZH2 1 item
  5. Bromodomains 2item
  6. FLT3 5item
  7. VEGFR 2item
  8. RET 1 item
  9. Hydrolase 1 item
  10. MEK 1 item
  11. FGFR 1 item
  12. Pim 1 item
  13. Sir2-like Family Deacetylases (Sirtuins) 2item
  14. PP1 1 item
  15. PP2A 1 item
  16. Src 3item
  17. Trk Receptors 1 item
  18. STAT 2item
  19. EGFR 1 item
  20. Hypoxia Inducible Factors (HIFs) 1 item
  21. JAK 10item
  22. Topoisomerases 1 item
  23. ErbB 1 item
  24. DNA Methyltransferases 1 item
  25. LRRK2 1 item
  26. PARP 2item
  27. ALK 1 item
  28. phosphatases 1 item
  29. Hck 1 item
  30. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  31. Cytidine deaminases 1 item
  32. PP4 1 item
  33. c-RET 1 item
  34. VEGFR3/FLT4 1 item
  35. NTRK1/TRKA 1 item
  36. CSF-1R/c-Fms 1 item
  37. PTP 1 item
  38. p53 1 item
  39. HDAC 1 item
  40. Histone Acetyltransferases (HATs) 1 item
  41. Trx 1 item
  42. TYK2 1 item
  43. MUSK 1 item
  44. MAP3K 1 item
  45. Lck 1 item
  46. p21 1 item
  47. FGR 1 item
  48. YES 1 item
  49. Fyn 1 item
  50. ARG 1 item
  51. Sirtuin 1 item
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  1. Acute Myeloid Leukemia 5item
  2. Bladder Cancer 2item
  3. Bladder Carcinoma 1 item
  4. Breast Cancer 7item
  5. Cancer 34item
  6. Cervical Cancer 1 item
  7. Chronic Lymphocytic Leukemia 1 item
  8. Colon Cancer 3item
  9. Colorectal Cancer 2item
  10. Glioblastoma 2item
  11. Glioma 1 item
  12. HIV 1 item
  13. HIV Infections 1 item
  14. Leukemia 1 item
  15. Lung Cancer 2item
  16. Melanoma 1 item
  17. Multiple Myeloma 1 item
  18. Myelofibrosis 1 item
  19. Neuroblastoma 1 item
  20. Neuronal Protection 1 item
  21. Non-small Cell Lung Cancer 1 item
  22. Ovarian Cancer 3item
  23. Pancreatic Cancer 2item
  24. Prostate Cancer 6item
  25. Psoriasis 1 item
  26. Renal Cancer 1 item
  27. Renal Cell Carcinoma 1 item
  28. Rheumatoid Arthritis 2item
  29. Thyroid Cancer 1 item
  30. Type 2 Diabetes 1 item