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  • Search results for: 'research area epigenetics hypoxia inducible factors'

Search results for: 'research area epigenetics hypoxia inducible factors'

Items 1-10 of 58

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  1. DMOG
    A4506 DMOG
    Target: Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs)
    Summary: Competitive HIF-PH inhibitor, cell-permeable
  2. Apicidin
    A8176 Apicidin
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: Potent HDAC inhibitor
      soluble in DMSO or ethanol
  3. Vorinostat (SAHA, MK0683)
    A4084 Vorinostat (SAHA, MK0683)
     9 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in EtOH; insoluble in H2O; ≥4.41 mg/mL
  4. Bardoxolone methyl
    A3221 Bardoxolone methyl
    Target: Nrf2
    Summary: IKK inhibitor, potent antioxidant inflammation modulator
      ≥25.3 mg/mL
  5. M344
    A4105 M344
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,potent and cell-permeable
  6. Mocetinostat (MGCD0103, MG0103)
    A4089 Mocetinostat (MGCD0103, MG0103)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,isotype-selective and potent
      insoluble in EtOH; insoluble in H2O; ≥19.8 mg/mL
  7. EPZ5676
    A4166 EPZ5676
     1 Citation
    Target: DOT1L
    Summary: DOT1L inhibitor,potent and SAM competitive
      ≥28.15 mg/mL
  8. AR-42 (OSU-HDAC42)
    A4104 AR-42 (OSU-HDAC42)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,novel and potent
      insoluble in EtOH; insoluble in H2O; ≥15.62 mg/mL
  9. AZD1208
    A3962 AZD1208
    Target: Pim
    Summary: PIM kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.95 mg/mL
  10. Tubacin
    A4501 Tubacin
     3 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC6 inhibitor,potent,selective,reversible,cell-permeable
      insoluble in EtOH; insoluble in H2O; ≥7.19 mg/mL

Items 1-10 of 58

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Category
  1. Bromodomain 3item
  2. Aurora Kinase 10item
  3. DNA Methyltransferase 4item
  4. HDAC 17item
  5. Histone Acetyltransferases 1 item
  6. Histone Demethylases 1 item
  7. Histone Methyltransferase 6item
  8. HIF 2item
  9. JAK 5item
  10. PARP 1 item
  11. Pim 2item
  12. Protein Ser/Thr Phosphatases 3item
  13. Sirtuin 4item
Reversibility
  1. Reversible 2item
Target
  1. Cyclin-Dependent Kinases 1 item
  2. Histone Deacetylases (HDACs) 17item
  3. Aurora Kinases 10item
  4. EZH2 2item
  5. Bromodomains 1 item
  6. FLT3 1 item
  7. Hydrolase 1 item
  8. MEK 1 item
  9. DOT1L 1 item
  10. Nrf2 1 item
  11. Pim 2item
  12. Sir2-like Family Deacetylases (Sirtuins) 3item
  13. PP1 1 item
  14. PP2A 1 item
  15. Src 1 item
  16. STAT 1 item
  17. Hypoxia Inducible Factors (HIFs) 1 item
  18. JAK 4item
  19. Topoisomerases 1 item
  20. DNA Methyltransferases 3item
  21. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  22. CREBBP 2item
  23. EP300 2item
  24. PARP 1 item
  25. phosphatases 1 item
  26. G9a 1 item
  27. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  28. Cytidine deaminases 1 item
  29. PP4 1 item
  30. c-RET 1 item
  31. Histone Acetyltransferases (HATs) 1 item
  32. Lck 1 item
  33. Sirtuin 1 item
Reported Experiments
  1. Animal Experiments 47item
  2. Cell Experiments 36item
Related Disease
  1. Acute Myeloid Leukemia 7item
  2. Bladder Cancer 2item
  3. Bladder Carcinoma 1 item
  4. Breast Cancer 13item
  5. Cancer 38item
  6. Cervical Cancer 1 item
  7. Chronic Lymphocytic Leukemia 1 item
  8. Colon Cancer 7item
  9. Colorectal Cancer 4item
  10. Diabetes 1 item
  11. Glioblastoma 2item
  12. Glioma 2item
  13. Hepatic Cancer 1 item
  14. Hepatocellular Carcinoma 1 item
  15. HIV Infections 1 item
  16. Leukemia 3item
  17. Lung Cancer 4item
  18. Lymphoma 2item
  19. Melanoma 1 item
  20. Mixed Lineage Leukemia 1 item
  21. Multiple Myeloma 3item
  22. Myelofibrosis 1 item
  23. Myeloma 1 item
  24. Neuroblastoma 1 item
  25. Neuronal Protection 1 item
  26. Non-small Cell Lung Cancer 2item
  27. Ovarian Cancer 5item
  28. Pancreatic Cancer 2item
  29. Prostate Cancer 10item
  30. Psoriasis 1 item
  31. Renal Cancer 1 item
  32. Renal Cell Carcinoma 2item
  33. Rheumatoid Arthritis 2item
  34. Thyroid Cancer 1 item
  35. Type 2 Diabetes 2item