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Search results for: 'research area epigenetics hypoxia inducible factors'

Search results for: 'research area epigenetics hypoxia inducible factors'

A8182 3-Deazaneplanocin A (DZNep) hydrochloride

1 Citation

Target: EZH2

Summary: SAHH and EZH2 inhibitor

insoluble in EtOH; ≥14.94 mg/mL
A4112 Barasertib (AZD1152-HQPA)

3 Citation

Target: Aurora Kinases

Summary: Aurora Kinase B inhibitor, Potent and selective

≥25.4 mg/mL
A8233 DMXAA (Vadimezan)

2 Citation

Target: DT-diaphorases

Summary: Tumnor vascular disrupting agent, apoptosis inducer

insoluble in H2O; insoluble in EtOH; ≥14.1 mg/mL
A8366 ARRY-380

Target: HER2

Summary: Tyrosine kinase HER2 and p95-HER2 inhibitor

≥28.5 mg/mL
A8628 Chloroquine diphosphate

1 Citation

Target: Autophagy

Summary: Antimalarial drug,TLR7 TLR9 inhibitor

insoluble in DMSO; insoluble in EtOH; ≥106.06 mg/mL
A8375 AZD8931 (Sapitinib)

Target: EGFR|ErbB

Summary: ErbB inhibitor

≥23.7 mg/mL
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
A8370 Axitinib (AG 013736)

1 Citation

Target: VEGFR|PDGFR|c-Kit

Summary: VEGFR1/ c-Kit inhibitor

insoluble in H2O; ≥19.3 mg/mL
A8252 Nintedanib (BIBF 1120)

3 Citation

Target: VEGFR|PDGFR|FGFR

Summary: VEGFR/PDGFR/FGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
N1846 Tanshinone IIA

Target: AP-1|MAGL

Summary: Antioxidant and anti-inflammatory reagent

insoluble in EtOH; insoluble in H2O; ≥3.42 mg/mL